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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10551
Species: Mus musculus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1 (alpha)
Acc ID: CHEBI:39308
Term: 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
Definition: An organochlorine compound that has formula C8H10Cl2O2.
Chemical ID: MESH:C069616
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1decreases activityISOEsr1 (Rattus norvegicus)6480464CTD3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid results in decreased activity of ESR1 proteinPMID:20410157
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