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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10368
Species: Mus musculus
RGD Object: Gene
Symbol: Abcc2
Name: ATP-binding cassette, sub-family member 2
Acc ID: CHEBI:28865
Term: taurocholic acid
Definition: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Chemical ID: MESH:D013656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc2increases expressionEXP 6480464CTDTaurocholic Acid results in increased expression of ABCC2 mRNAPMID:27160211
Abcc2increases activityISOAbcc2 (Rattus norvegicus)6480464CTDTaurocholic Acid results in increased activity of ABCC2 protein; Taurocholic Acid results in increased activity of ABCC2 protein modified formPMID:15904671
Abcc2multiple interactionsISOAbcc2 (Rattus norvegicus)6480464CTDTaurocholic Acid results in increased expression of and results in increased activity of ABCC2 proteinPMID:12644037
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