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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10230
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2
Name: B cell leukemia/lymphoma 2
Acc ID: CHEBI:78677
Term: 6-anilino-5,8-quinolinedione
Definition: A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.
Chemical ID: MESH:C041715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTD6-anilino-5,8-quinolinedione results in decreased expression of BCL2 proteinPMID:18544562
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD6-anilino-5,8-quinolinedione inhibits the reaction [sodium bichromate results in increased ubiquitination of BCL2 protein]PMID:18544562
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