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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10230
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2
Name: B cell leukemia/lymphoma 2
Acc ID: CHEBI:3015
Term: benomyl
Definition: A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops.
Chemical ID: MESH:D001542
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2increases phosphorylationISOBCL2 (Homo sapiens)6480464CTDBenomyl results in increased phosphorylation of BCL2 proteinPMID:16903866
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTDBenomyl inhibits the reaction [BCL2 protein binds to BAX protein]PMID:16903866
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