Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	10199
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Atm
Name:	ataxia telangiectasia mutated

Acc ID:	CHEBI:50859
Term:	bexarotene
Definition:	A retinoid that has formula C24H28O2.
Chemical ID:	MESH:C095105

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Atm	increases activity	ISO	ATM (Homo sapiens)	6480464	CTD	bexarotene results in increased activity of ATM protein	PMID:19067706

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.