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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10147
Species: Mus musculus
RGD Object: Gene
Symbol: Alox5
Name: arachidonate 5-lipoxygenase
Acc ID: CHEBI:2981
Term: baicalin
Definition: The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis.
Chemical ID: MESH:C038044
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alox5multiple interactionsISOAlox5 (Rattus norvegicus)6480464CTDbaicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein]PMID:20139896
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