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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10133
Species: Mus musculus
RGD Object: Gene
Symbol: Alad
Name: aminolevulinate, delta-, dehydratase
Acc ID: CHEBI:16602
Term: trichloroethene
Definition: A member of the class of chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.
Chemical ID: MESH:D014241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aladdecreases activityISOAlad (Rattus norvegicus)6480464CTDTrichloroethylene results in decreased activity of ALAD proteinPMID:6710543
Aladdecreases activityISOALAD (Homo sapiens)6480464CTDTrichloroethylene results in decreased activity of ALAD proteinPMID:16140629
Aladmultiple interactionsISOAlad (Rattus norvegicus)6480464CTDPhenobarbital affects the reaction [Trichloroethylene results in decreased activity of ALAD protein]PMID:6710543
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