RGD Annotation Report for Down syndromeRat Genome Database

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An association has been curated linking Ctss and Down syndrome in Rattus norvegicus.

The association was inferred from sequence orthology (ISO)
The annotation was made from Lemere CA, etal., Am J Pathol. 1995 Apr;146(4):848-60.
The annotation has been inferred from sequence orthology with CTSS (Homo sapiens) [(IEP) inferred from expression pattern]
5 additional annotations were made from Lemere CA, etal., Am J Pathol. 1995 Apr;146(4):848-60.
62 RGD objects have been annotated to Down syndrome (DOID:14250)
31 papers in RGD have been used to annotate Ctss

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.