Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

2 Annotations Found.

An association has been curated linking Src and positive regulation of ERK1 and ERK2 cascade in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Choudhury GG, etal., Cell Signal. 2006 Nov;18(11):1854-64.
  • 9 additional annotations were made from Choudhury GG, etal., Cell Signal. 2006 Nov;18(11):1854-64.
  • 230 RGD objects have been annotated to positive regulation of ERK1 and ERK2 cascade  (GO:0070374)
  • 110 papers in RGD have been used to annotate Src
  • Qualifier: involved_in
  • Curation Notes: PMID:16530387


    • An association has been curated linking Src and positive regulation of ERK1 and ERK2 cascade in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD pipelines: Rat ISO annotations derived from the GO annotations of orthologous genes in other species.
  • The annotation has been inferred from sequence orthology with Src (Mus musculus)
  • 230 RGD objects have been annotated to positive regulation of ERK1 and ERK2 cascade  (GO:0070374)
  • 110 papers in RGD have been used to annotate Src
  • Qualifier: involved_in
  • Curation Notes: (MGI:3690285|PMID:17045821)
  • Original References(s): MGI:3690285 PMID:17045821


    • Go Back to source page   Continue to Ontology report