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GENE - TERM ANNOTATION REPORT

5 Annotations Found.

An association has been curated linking Pon1 and macular degeneration in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Esfandiary H, etal., Br J Ophthalmol. 2005 Apr;89(4):470-4.
  • The annotation has been inferred from sequence orthology with PON1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Esfandiary H, etal., Br J Ophthalmol. 2005 Apr;89(4):470-4.
  • 161 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 99 papers in RGD have been used to annotate Pon1
  • Qualifier: no_association
  • Curation Notes: DNA:missense mutations:cds:p.L55M, p.Q192R (rs662, rs854560) (human)


    • An association has been curated linking Pon1 and macular degeneration in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Ugurlu N, etal., Curr Eye Res. 2013 Apr;38(4):497-502. doi: 10.3109/02713683.2013.774023. Epub 2013 Feb 22.
  • The annotation has been inferred from sequence orthology with PON1 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Ugurlu N, etal., Curr Eye Res. 2013 Apr;38(4):497-502. doi: 10.3109/02713683.2013.774023. Epub 2013 Feb 22.
  • 161 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 99 papers in RGD have been used to annotate Pon1
  • Curation Notes: protein:decreased activity:serum (human)


    • An association has been curated linking Pon1 and macular degeneration in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Sogut E, etal., Retina. 2013 Oct;33(9):1836-42. doi: 10.1097/IAE.0b013e318287da59.
  • The annotation has been inferred from sequence orthology with PON1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Sogut E, etal., Retina. 2013 Oct;33(9):1836-42. doi: 10.1097/IAE.0b013e318287da59.
  • 161 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 99 papers in RGD have been used to annotate Pon1
  • Qualifier: susceptibility
  • Curation Notes: DNA:missense mutations:cds:p.L55M, p.Q192R (human)


    • An association has been curated linking Pon1 and macular degeneration in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Baird PN, etal., Am J Ophthalmol. 2004 Oct;138(4):665-6.
  • The annotation has been inferred from sequence orthology with PON1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 4 additional annotations were made from Baird PN, etal., Am J Ophthalmol. 2004 Oct;138(4):665-6.
  • 161 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 99 papers in RGD have been used to annotate Pon1
  • Qualifier: no_association
  • Curation Notes: DNA:missense mutations:cds:p.L55M, p.Q192R (human)


    • An association has been curated linking Pon1 and macular degeneration in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Oczos J, etal., Age (Dordr). 2013 Oct;35(5):1651-62. doi: 10.1007/s11357-012-9467-x. Epub 2012 Sep 7.
  • The annotation has been inferred from sequence orthology with PON1 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 5 additional annotations were made from Oczos J, etal., Age (Dordr). 2013 Oct;35(5):1651-62. doi: 10.1007/s11357-012-9467-x. Epub 2012 Sep 7.
  • 161 RGD objects have been annotated to macular degeneration  (DOID:4448)
  • 99 papers in RGD have been used to annotate Pon1
  • Qualifier: susceptibility
  • Curation Notes: DNA:snps:promoter, 5' utr:multiple (human)


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