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GENE - TERM ANNOTATION REPORT

2 Annotations Found.

An association has been curated linking Apc and colon adenocarcinoma in Rattus norvegicus.        

  • The association was inferred from mutant phenotype (IMP)
    		•  
  • The annotation was made from Amos-Landgraf JM, etal., Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4036-41. Epub 2007 Feb 27.
  • 54 additional annotations were made from Amos-Landgraf JM, etal., Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4036-41. Epub 2007 Feb 27.
  • 65 RGD objects have been annotated to colon adenocarcinoma  (DOID:234)
  • 62 papers in RGD have been used to annotate Apc
  • Curation Notes: associated with Adenomatous Polyposis Coli;DNA:point mutation:CDS:p.K1137X (3409A>T) (rat)


    • An association has been curated linking Apc and colon adenocarcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with APC (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 65 RGD objects have been annotated to colon adenocarcinoma  (DOID:234)
  • 62 papers in RGD have been used to annotate Apc
  • Curation Notes: ClinVar Annotator: match by term: Colon adenocarcinoma
  • Original References(s): PMID:24033266 PMID:24728327 PMID:25741868 PMID:27978560 PMID:28492532


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