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GENE - TERM ANNOTATION REPORT

6 Annotations Found.

An association has been curated linking Cdkn2a and acute lymphoblastic leukemia in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Xu H, etal., Nat Commun. 2015 Jun 24;6:7553. doi: 10.1038/ncomms8553.
  • The annotation has been inferred from sequence orthology with CDKN2A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 5 additional annotations were made from Xu H, etal., Nat Commun. 2015 Jun 24;6:7553. doi: 10.1038/ncomms8553.
  • 276 RGD objects have been annotated to acute lymphoblastic leukemia  (DOID:9952)
  • 102 papers in RGD have been used to annotate Cdkn2a
  • Qualifier: susceptibility
  • Curation Notes: DNA:missense mutations:cds:


    • An association has been curated linking Cdkn2a and acute lymphoblastic leukemia in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Maloney KW, etal., Blood. 1999 Apr 1;93(7):2380-5.
  • The annotation has been inferred from sequence orthology with CDKN2A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 5 additional annotations were made from Maloney KW, etal., Blood. 1999 Apr 1;93(7):2380-5.
  • 276 RGD objects have been annotated to acute lymphoblastic leukemia  (DOID:9952)
  • 102 papers in RGD have been used to annotate Cdkn2a
  • Qualifier: disease_progression
  • Curation Notes: DNA:deletion: :


    • An association has been curated linking Cdkn2a and acute lymphoblastic leukemia in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Maloney KW, etal., Leukemia. 1997 Jul;11(7):979-83.
  • The annotation has been inferred from sequence orthology with CDKN2A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Maloney KW, etal., Leukemia. 1997 Jul;11(7):979-83.
  • 276 RGD objects have been annotated to acute lymphoblastic leukemia  (DOID:9952)
  • 102 papers in RGD have been used to annotate Cdkn2a
  • Qualifier: no_association
  • Curation Notes: DNA:deletion: :


    • An association has been curated linking Cdkn2a and acute lymphoblastic leukemia in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Chien WW, etal., Leuk Res. 2015 Apr;39(4):453-61. doi: 10.1016/j.leukres.2015.01.008. Epub 2015 Jan 25.
  • The annotation has been inferred from sequence orthology with CDKN2A (Homo sapiens) [(IEP) inferred from expression pattern]
  • 3 additional annotations were made from Chien WW, etal., Leuk Res. 2015 Apr;39(4):453-61. doi: 10.1016/j.leukres.2015.01.008. Epub 2015 Jan 25.
  • 276 RGD objects have been annotated to acute lymphoblastic leukemia  (DOID:9952)
  • 102 papers in RGD have been used to annotate Cdkn2a
  • Qualifier: disease_progression


    • An association has been curated linking Cdkn2a and acute lymphoblastic leukemia in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with CDKN2A (Homo sapiens) [(EXP) inferred from experiment]
  • 276 RGD objects have been annotated to acute lymphoblastic leukemia  (DOID:9952)
  • 102 papers in RGD have been used to annotate Cdkn2a
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:20453839


    • An association has been curated linking Cdkn2a and acute lymphoblastic leukemia in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with CDKN2A (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 276 RGD objects have been annotated to acute lymphoblastic leukemia  (DOID:9952)
  • 102 papers in RGD have been used to annotate Cdkn2a
  • Curation Notes: ClinVar Annotator: match by term: Acute lymphocytic leukemia | ClinVar Annotator: match by term: Acute lymphoid leukemia
  • Original References(s): PMID:10389768 PMID:10667595 PMID:10719365 PMID:11518711 PMID:11687599 PMID:15075790 PMID:16234564 PMID:16818274 PMID:16896043 PMID:17218939 PMID:18335566 PMID:18519632 PMID:21085193 PMID:21462282 PMID:22440936 PMID:24733792 PMID:25078331 PMID:25741868 PMID:25980754 PMID:26467025 PMID:26670561 PMID:26681309 PMID:27756164 PMID:27960642 PMID:27993330 PMID:28454591 PMID:28492532 PMID:28640387 PMID:28765326 PMID:28830827 PMID:30207590 PMID:30339520 PMID:31921681 PMID:32191290 PMID:33823155 PMID:35001868 PMID:7566978 PMID:7647780 PMID:7718873 PMID:7987387 PMID:8573142 PMID:9166859 PMID:9389568 PMID:9823374


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