Phenominer Database Results (24 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87.0 days 5 24.5 uV 4.9 10.96 electroretinography cornea 0.0 plasmid delivery 71 days scotopic a-wave ERG 108734 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108701 3131
RCS-p+/LavRrrc retinal inner nuclear layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal inner nuclear layer morphology trait both 51.0 days 5 19.6 um 0.5 1.12 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 35 days retinal inner nuclear layer thickness (CMO:0003668) 108708 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 231.0 uV 5.0 8.66 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic b-wave ERG 108749 3131
RCS-p+/LavRrrc retinal outer nuclear layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal outer nuclear layer morphology trait both 75.0 days 5 14.4 um 1.5 3.35 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 55 days 108699 3131
RCS-p+/LavRrrc photoreceptor inner segment thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. photoreceptor inner segment morphology trait both 51.0 days 5 6.4 um 0.3 0.67 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 35 days superior hemisphere - photoreceptor IS 108712 3131
RCS-p+/LavRrrc retinal outer nuclear layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal outer nuclear layer morphology trait both 70.0 days 5 8.5 um 0.7 1.57 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 54 days superior hemisphere 108718 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 60.2 uV 8.5 19.01 electroretinography cornea 0.0 plasmid delivery 37 days scotopic a-wave ERG 108726 3131
RCS-p+/LavRrrc photoreceptor inner segment thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. photoreceptor inner segment morphology trait both 70.0 days 4 9.2 um 1.0 2.0 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 54 days superior hemisphere 108743 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108728 3131
RCS-p+/LavRrrc retinal inner nuclear layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal inner nuclear layer morphology trait both 75.0 days 5 29.9 um 1.5 3.35 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 55 days 108697 3131
RCS-p+/LavRrrc photoreceptor inner segment thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. photoreceptor inner segment morphology trait both 70.0 days 5 0.9 um 0.2 0.45 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 54 days superior hemisphere - photoreceptor IS 108716 3131
RCS-p+/LavRrrc retinal outer nuclear layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal outer nuclear layer morphology trait both 87.0 days 5 4.7 um 0.7 1.57 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 71 days superior hemisphere 108722 3131
RCS-p+/LavRrrc retinal outer nuclear layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal outer nuclear layer morphology trait both 70.0 days 4 17.6 um 1.7 3.4 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 54 days superior hemisphere 108740 3131
RCS-p+/LavRrrc retinal inner layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal inner nuclear layer morphology trait both 70.0 days 5 20.1 um 0.6 1.34 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 54 days superior hemisphere 108714 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 114.0 uV 16.0 35.78 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108732 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 23.1 uV 4.0 8.94 electroretinography cornea 0.0 plasmid delivery 59 days scotopic a-wave ERG 108730 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87.0 days 5 110.0 uV 14.0 31.3 electroretinography cornea 0.0 plasmid delivery 71 days scotopic b-wave ERG 108736 3131
RCS-p+/LavRrrc photoreceptor inner segment thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. photoreceptor inner segment morphology trait both 87.0 days 5 1.1 um 0.5 1.12 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 71 days superior hemisphere - photoreceptor IS 108724 3131
RCS-p+/LavRrrc retinal inner layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal inner nuclear layer morphology trait both 70.0 days 4 30.5 um 1.3 2.6 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 54 days superior hemisphere 108737 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 23.8 uV 1.9 3.29 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic a-wave ERG 108746 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 114.0 uV 16.1 36.0 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108703 3131
RCS-p+/LavRrrc retinal outer nuclear layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal outer nuclear layer morphology trait both 51.0 days 5 22.2 um 0.9 2.01 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 35 days superior hemisphere 108710 3131
RCS-p+/LavRrrc retinal inner layer thickness sham gene transfer using an empty plasmid vector pVAX2 (30 ug) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. retinal inner nuclear layer morphology trait both 87.0 days 5 20.8 um 0.9 2.01 ex vivo light microscopy with histochemistry and digital image analysis 0.0 plasmid delivery 71 days superior hemisphere 108720 3131