Phenominer Database Results (50 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87.0 days 5 83.0 uV 7.0 15.65 electroretinography cornea 0.0 plasmid delivery 71 days pVAX2-rGDNF scotopic b-wave ERG 108735 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87.0 days 5 24.5 uV 4.9 10.96 electroretinography cornea 0.0 plasmid delivery 71 days scotopic a-wave ERG 108734 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108701 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 231.0 uV 5.0 8.66 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic b-wave ERG 108749 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 475.0 uV 41.0 91.68 electroretinography cornea 0.0 plasmid delivery 37 days pVAX2-rGDNF scotopic b-wave ERG 108727 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 33.73 uV 9.28 24.55 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108540 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 192.0 uV 14.42 38.15 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108545 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 233.29 uV 18.61 49.24 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108546 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 19.05 uV 3.75 9.92 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108550 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 159.83 uV 21.35 56.49 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108558 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 11.45 uV 3.56 9.42 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108537 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 186.0 uV 23.8 53.22 electroretinography cornea 0.0 37 days control for age matched plasmid injection scotopic b-wave ERG 108702 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 60.2 uV 8.5 19.01 electroretinography cornea 0.0 plasmid delivery 37 days scotopic a-wave ERG 108726 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 20.9 uV 3.7 6.41 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic a-wave ERG 108748 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108728 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 83.4 uV 14.8 39.16 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108543 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 145.24 uV 12.56 33.23 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108544 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 31.22 uV 8.16 21.59 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108551 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 179.49 uV 20.75 54.9 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108559 3123
RCS-p+/LavRrrc photopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. cone electrophysiology trait not specified 119.0 days 7 23.1 uV 1.0 2.65 electroretinography cornea 0.0 intravitrial injection 98 days 109739 3154
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 24.7 uV 13.8 30.86 electroretinography cornea 0.0 59 days control for age matched plasmid injection scotopic b-wave ERG 108704 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 199.0 uV 17.0 29.44 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic b-wave ERG 108750 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 114.0 uV 16.0 35.78 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108732 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 23.1 uV 4.0 8.94 electroretinography cornea 0.0 plasmid delivery 59 days scotopic a-wave ERG 108730 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 5.86 uV 0.76 2.01 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108536 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 7.44 uV 1.43 3.78 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108542 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 94.13 uV 15.33 40.56 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108556 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87.0 days 5 17.1 uV 3.2 7.16 electroretinography cornea 0.0 plasmid delivery 71 days pVAX2-rGDNF scotopic a-wave ERG 108733 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87.0 days 5 110.0 uV 14.0 31.3 electroretinography cornea 0.0 plasmid delivery 71 days scotopic b-wave ERG 108736 3131
RCS-p+/LavRrrc optokinetic reflex GSK-812 (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. eye physiology trait not specified 119.0 days 7 8.2 s 0.4 1.06 optokinetic reflex test method 60.0 intravitrial injection 98 days 109742 3154
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53.0 days 5 96.3 uV 10.3 23.03 electroretinography cornea 0.0 plasmid delivery 37 days pVAX2-rGDNF scotopic a-wave ERG 108725 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 23.8 uV 1.9 3.29 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic a-wave ERG 108746 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 135.0 uV 38.0 84.97 electroretinography cornea 0.0 plasmid delivery 59 days pVAX2-rGDNF scotopic b-wave ERG 108731 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 18.53 uV 4.77 12.63 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108538 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 36.49 uV 10.37 27.44 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108541 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 3.13 uV 1.81 4.79 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108548 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 251.29 uV 19.14 50.64 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108547 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 24.79 uV 7.82 20.69 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108552 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 31.96 uV 9.73 25.74 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108553 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 10.28 uV 1.69 4.47 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108554 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 32.75 uV 13.42 35.51 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108555 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 131.7 uV 16.13 42.68 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108557 3123
RCS-p+/LavRrrc photopic B wave amplitude of ERG waveform GSK-812 (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. cone electrophysiology trait not specified 119.0 days 7 28.9 uV 2.5 6.61 electroretinography cornea 0.0 intravitrial injection 98 days 109740 3154
RCS-p+/LavRrrc optokinetic reflex vehicle control condition (2 ul) then visible light stimulus (25 cd x s/m2) Baranov P, et al., J Ocul Pharmacol Ther. 2017 Jun;33(5):412-422. doi: 10.1089/jop.2016.0121. Epub 2017 Apr 25. eye physiology trait not specified 119.0 days 7 6.0 s 0.27 0.71 optokinetic reflex test method 60.0 intravitrial injection 98 days 109741 3154
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform sham gene transfer using an empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 114.0 uV 16.1 36.0 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108703 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75.0 days 5 29.7 uV 11.3 25.27 electroretinography cornea 0.0 plasmid delivery 59 days pVAX2-rGDNF scotopic a-wave ERG 108729 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 26.7 uV 2.7 4.68 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic a-wave ERG 108747 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70.0 days 3 144.0 uV 29.0 50.23 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic b-wave ERG 108751 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 27.22 uV 4.74 12.54 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108539 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39.0 days 7 15.31 uV 2.98 7.88 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108549 3123