| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 5 |
3.3 |
/ 100 um |
2.8 |
6.26 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
contralateral control eye |
|
107362 |
3082 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 5 |
1.8 |
/ 100 um |
1.9 |
4.25 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
contralateral control eye |
|
107372 |
3082 |
| RCS-p+/LavRrrc |
scotopic A wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) |
Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. |
rod electrophysiology trait |
both |
34.0 days
| 8 |
13.0 |
uV |
13.0 |
36.77 |
electroretinography |
|
0.0 |
|
|
untreated control |
electrical activity measurement of retina (CMO:0003653)/A wave |
108374 |
3121 |
| RCS-p+/LavRrrc |
scotopic A wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) |
Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. |
rod electrophysiology trait |
both |
48.0 days
| 5 |
17.0 |
uV |
5.0 |
11.18 |
electroretinography |
|
0.0 |
|
|
untreated control |
a-wave amplitude ERG |
108380 |
3121 |
| RCS-p+/LavRrrc |
scotopic B wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) |
Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. |
rod electrophysiology trait |
both |
62.0 days
| 5 |
13.0 |
uV |
17.0 |
38.01 |
electroretinography |
|
0.0 |
|
|
untreated control |
b-wave amplitude ERG |
108389 |
3121 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 5 |
2.4 |
/ 100 um |
3.2 |
7.16 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
contralateral control eye |
|
107364 |
3082 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 5 |
3.5 |
/ 100 um |
3.0 |
6.71 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
contralateral control eye |
|
107370 |
3082 |
| RCS-p+/LavRrrc |
scotopic B wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) |
Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. |
rod electrophysiology trait |
both |
34.0 days
| 8 |
45.0 |
uV |
42.0 |
118.79 |
electroretinography |
|
0.0 |
|
|
untreated control |
b-wave amplitude ERG |
108377 |
3121 |
| RCS-p+/LavRrrc |
retinal inner nuclear layer thickness |
control condition |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
retinal inner nuclear layer morphology trait |
both |
75.0 days
| 3 |
25.1 |
um |
1.3 |
2.25 |
ex vivo light microscopy with histochemistry and digital image analysis |
|
0.0 |
55 |
days |
control for age matched plasmid injection |
|
108698 |
3131 |
| RCS-p+/LavRrrc |
scotopic B wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
rod electrophysiology trait |
both |
53.0 days
| 5 |
186.0 |
uV |
23.8 |
53.22 |
electroretinography |
cornea |
0.0 |
37 |
days |
control for age matched plasmid injection |
scotopic b-wave ERG |
108702 |
3131 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 8 |
3.3 |
/ 100 um |
2.8 |
7.92 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
|
|
109122 |
3082 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 5 |
2.9 |
/ 100 um |
3.0 |
6.71 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
contralateral control eye |
|
107368 |
3082 |
| RCS-p+/LavRrrc |
scotopic B wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
rod electrophysiology trait |
both |
75.0 days
| 5 |
24.7 |
uV |
13.8 |
30.86 |
electroretinography |
cornea |
0.0 |
59 |
days |
control for age matched plasmid injection |
scotopic b-wave ERG |
108704 |
3131 |
| RCS-p+/LavRrrc |
scotopic B wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) |
Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. |
rod electrophysiology trait |
both |
48.0 days
| 5 |
48.0 |
uV |
26.0 |
58.14 |
electroretinography |
|
0.0 |
|
|
untreated control |
b-wave amplitude ERG |
108383 |
3121 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 5 |
3.4 |
/ 100 um |
3.7 |
8.27 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
contralateral control eye |
|
107366 |
3082 |
| RCS-p+/LavRrrc |
scotopic A wave amplitude of ERG waveform |
control condition then controlled exposure to darkness (for 12 hours) |
Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. |
rod electrophysiology trait |
both |
62.0 days
| 5 |
8.9 |
uV |
9.9 |
22.14 |
electroretinography |
|
0.0 |
|
|
untreated control |
a-wave amplitude ERG |
108386 |
3121 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer thickness |
control condition |
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. |
retinal outer nuclear layer morphology trait |
both |
75.0 days
| 3 |
8.1 |
um |
1.2 |
2.08 |
ex vivo light microscopy with histochemistry and digital image analysis |
|
0.0 |
55 |
days |
control for age matched plasmid injection |
|
108700 |
3131 |
| RCS-p+/LavRrrc |
retinal outer nuclear layer photoreceptor nucleus count to layer length ratio |
control condition |
Kang S, et al., Transl Vis Sci Technol. 2019 Aug 7;8(4):19. doi: 10.1167/tvst.8.4.19. eCollection 2019 Jul. |
retinal photoreceptor quantity |
not specified |
180.0 days
| 8 |
2.3 |
/ 100 um |
1.3 |
3.68 |
ex vivo light microscopy with histochemistry |
|
0.0 |
|
|
contralateral control eye |
|
109068 |
3082 |