| DDI/Ddia |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
42.0 days
| 6 |
|
174.2 |
g |
4.78 |
11.7 |
whole body digital scale |
|
|
|
|
71102 |
21 |
| DDI/Ddia |
plasma glucose level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood glucose amount |
male |
70.0 days
| 6 |
|
148.0 |
mg/dl |
5.72 |
14.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81900 |
1498 |
| DDI/Ddia |
plasma low density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood LDL cholesterol amount |
male |
70.0 days
| 6 |
|
7.0 |
mg/dl |
0.41 |
1.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81903 |
1498 |
| DDI/Ddia |
blood lymphocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
lymphocyte quantity |
male |
70.0 days
| 6 |
|
81.0 |
% |
2.45 |
6.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
81917 |
1498 |
| DDI/Ddia |
blood monocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
monocyte quantity |
male |
70.0 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
81918 |
1498 |
| DDI/Ddia |
lung weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70.0 days
| 6 |
|
0.37 |
% |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73762 |
41 |
| DDI/Ddia |
lung wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70.0 days
| 6 |
|
1.15 |
g |
0.06 |
0.14 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73761 |
41 |
| DDI/Ddia |
liver wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70.0 days
| 6 |
|
8.79 |
g |
0.3 |
0.74 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73763 |
41 |
| DDI/Ddia |
liver weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70.0 days
| 6 |
|
2.85 |
% |
0.04 |
0.09 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73764 |
41 |
| DDI/Ddia |
both adrenal glands wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70.0 days
| 6 |
|
67.3 |
mg |
4.2 |
10.3 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73767 |
41 |
| DDI/Ddia |
blood hemoglobin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
15.8 |
g/dl |
0.08 |
0.2 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81885 |
1498 |
| DDI/Ddia |
hematocrit |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70.0 days
| 6 |
|
57.0 |
% |
1.47 |
3.6 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81886 |
1498 |
| DDI/Ddia |
mean corpuscular volume |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte size trait |
male |
70.0 days
| 6 |
|
64.1 |
fl |
1.47 |
3.6 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81887 |
1498 |
| DDI/Ddia |
mean corpuscular hemoglobin concentration |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
27.8 |
g/dl |
0.65 |
1.6 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81889 |
1498 |
| DDI/Ddia |
mean corpuscular hemoglobin |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
17.8 |
pg |
0.08 |
0.2 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81888 |
1498 |
| DDI/Ddia |
white blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70.0 days
| 6 |
|
7.0 |
x 1000 cells/ul |
0.24 |
0.6 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81890 |
1498 |
| DDI/Ddia |
activated partial thromboplastin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70.0 days
| 6 |
|
18.5 |
s |
0.61 |
1.5 |
automated coagulometer method |
|
|
Sysmex, CA-3000 type |
|
81893 |
1498 |
| DDI/Ddia |
plasma alkaline phosphatase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alkaline phosphatase amount |
male |
70.0 days
| 6 |
|
331.0 |
IU/l |
8.98 |
22.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81896 |
1498 |
| DDI/Ddia |
plasma total protein level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood total protein amount |
male |
70.0 days
| 6 |
|
62.0 |
mg/ml |
0.82 |
2.0 |
automated plasma total protein analysis |
|
|
Hitachi, model 7170 |
|
81897 |
1498 |
| DDI/Ddia |
plasma high density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood HDL cholesterol amount |
male |
70.0 days
| 6 |
|
44.4 |
mg/dl |
1.43 |
3.5 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81902 |
1498 |
| DDI/Ddia |
plasma creatinine level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood creatinine amount |
male |
70.0 days
| 6 |
|
0.35 |
mg/dl |
0.0 |
0.01 |
automated plasma creatinine analysis |
|
|
Hitachi, model 7170 |
|
81907 |
1498 |
| DDI/Ddia |
plasma chloride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood chloride amount |
male |
70.0 days
| 6 |
|
104.0 |
mmol/l |
0.41 |
1.0 |
automated blood electrolyte analysis |
|
|
Analytical intruments, PVA alpha II |
|
81912 |
1498 |
| DDI/Ddia |
blood band neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
band neutrophil % |
81915 |
1498 |
| DDI/Ddia |
blood basophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
basophil quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
81913 |
1498 |
| DDI/Ddia |
brain weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70.0 days
| 6 |
|
0.63 |
% |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73758 |
41 |
| DDI/Ddia |
heart wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70.0 days
| 6 |
|
1.06 |
g |
0.04 |
0.09 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73759 |
41 |
| DDI/Ddia |
both testes wet weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70.0 days
| 6 |
|
0.85 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73772 |
41 |
| DDI/Ddia |
urine chloride level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63.0 days
| 6 |
|
38.0 |
mEq/L |
11.02 |
27.0 |
automated urine analysis |
|
|
|
|
95994 |
1662 |
| DDI/Ddia |
urine chloride excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63.0 days
| 6 |
|
303.0 |
uEq/100g/6 hrs |
91.86 |
225.0 |
automated urine analysis |
|
|
|
|
95995 |
1662 |
| DDI/Ddia |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
70.0 days
| 6 |
|
326.9 |
g |
7.8 |
19.1 |
whole body digital scale |
|
|
|
|
71103 |
21 |
| DDI/Ddia |
plasma aspartate aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood aspartate transaminase amount |
male |
70.0 days
| 6 |
|
88.0 |
U/l |
2.04 |
5.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81894 |
1498 |
| DDI/Ddia |
plasma alanine aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alanine transaminase amount |
male |
70.0 days
| 6 |
|
43.0 |
U/l |
1.22 |
3.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81895 |
1498 |
| DDI/Ddia |
plasma total cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood cholesterol amount |
male |
70.0 days
| 6 |
|
65.0 |
mg/dl |
2.04 |
5.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81901 |
1498 |
| DDI/Ddia |
plasma total bilirubin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood bilirubin amount |
male |
70.0 days
| 6 |
|
0.01 |
mg/dl |
0.0 |
0.01 |
automated plasma analysis |
|
|
PMID:15591307 |
total plasma bilirubin level |
81905 |
1498 |
| DDI/Ddia |
plasma sodium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood sodium amount |
male |
70.0 days
| 6 |
|
147.0 |
mmol/l |
0.57 |
1.4 |
automated blood electrolyte analysis |
|
|
Analytical intruments, PVA alpha II |
|
81910 |
1498 |
| DDI/Ddia |
non-specified leukocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
unidentified differential wbc |
81919 |
1498 |
| DDI/Ddia |
heart weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70.0 days
| 6 |
|
3.45 |
g/kg |
0.12 |
0.29 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73760 |
41 |
| DDI/Ddia |
both adrenal glands weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70.0 days
| 6 |
|
21.7 |
mg/100g |
0.82 |
2.0 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73768 |
41 |
| DDI/Ddia |
both kidneys wet weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70.0 days
| 6 |
|
0.66 |
% |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73766 |
41 |
| DDI/Ddia |
both testes wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70.0 days
| 6 |
|
2.62 |
g |
0.06 |
0.14 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73771 |
41 |
| DDI/Ddia |
timed urine volume to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63.0 days
| 6 |
|
0.22 |
ul/min/g |
0.01 |
0.02 |
metabolic cage urine volume measurement method |
|
|
|
|
95989 |
1662 |
| DDI/Ddia |
urine potassium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63.0 days
| 6 |
|
21.7 |
mmol/l |
2.53 |
6.2 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95992 |
1662 |
| DDI/Ddia |
urine potassium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63.0 days
| 6 |
|
175.0 |
uEq/100g/6 hrs |
23.27 |
57.0 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95993 |
1662 |
| DDI/Ddia |
heart rate |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
heart pumping trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
392.0 |
beats/min |
8.98 |
22.0 |
tail cuff photoplethysmography |
|
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75358 |
14 |
| DDI/Ddia |
body temperature |
specific pathogen-free condition |
NBRP Body Temperature data |
body temperature trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
37.6 |
degrees C |
0.08 |
0.2 |
digital rectal thermometry |
|
|
|
|
75359 |
22 |
| DDI/Ddia |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
35.0 days
| 6 |
|
112.9 |
g |
4.04 |
9.9 |
whole body digital scale |
|
|
|
|
71101 |
21 |
| DDI/Ddia |
platelet count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
platelet quantity |
male |
70.0 days
| 6 |
|
1209.0 |
x 1000 /ul |
11.02 |
27.0 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81891 |
1498 |
| DDI/Ddia |
plasma albumin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70.0 days
| 6 |
|
0.36 |
g/l |
0.0 |
0.01 |
automated plasma albumin analysis |
|
|
Hitachi, model 7170 |
|
81898 |
1498 |
| DDI/Ddia |
plasma urea nitrogen level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood urea nitrogen amount |
male |
70.0 days
| 6 |
|
8.6 |
mmol/l |
0.57 |
1.39 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81906 |
1498 |
| DDI/Ddia |
plasma triglyceride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood triglyceride amount |
male |
70.0 days
| 6 |
|
0.64 |
mmol/l |
0.05 |
0.12 |
automated plasma analysis |
|
|
PMID:15591307 |
|
81904 |
1498 |
| DDI/Ddia |
plasma phosphate level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood phosphate amount |
male |
70.0 days
| 6 |
|
6.4 |
mg/dl |
0.16 |
0.4 |
automated blood electrolyte analysis |
|
|
Hitachi, model 7170 |
|
81908 |
1498 |
| DDI/Ddia |
plasma potassium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood potassium amount |
male |
70.0 days
| 6 |
|
3.42 |
mmol/l |
0.09 |
0.23 |
automated blood electrolyte analysis |
|
|
Analytical intruments, PVA alpha II |
|
81911 |
1498 |
| DDI/Ddia |
blood eosinophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
eosinophil quantity |
male |
70.0 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
81914 |
1498 |
| DDI/Ddia |
brain wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70.0 days
| 6 |
|
1.94 |
g |
0.02 |
0.06 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73757 |
41 |
| DDI/Ddia |
both kidneys wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70.0 days
| 6 |
|
2.04 |
g |
0.07 |
0.17 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73765 |
41 |
| DDI/Ddia |
spleen wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70.0 days
| 6 |
|
0.8 |
g |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73769 |
41 |
| DDI/Ddia |
timed urine volume |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63.0 days
| 6 |
|
102.0 |
ml/d |
3.63 |
8.88 |
metabolic cage urine volume measurement method |
|
|
|
|
95988 |
1662 |
| DDI/Ddia |
urine sodium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63.0 days
| 6 |
|
0.01 |
uEq/min/g |
0.0 |
0.01 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95991 |
1662 |
| DDI/Ddia |
systolic blood pressure |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
arterial blood pressure trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
147.0 |
mmHg |
2.04 |
5.0 |
tail cuff photoplethysmography |
|
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75357 |
14 |
| DDI/Ddia |
red blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70.0 days
| 6 |
|
8.88 |
x 10E6 cells/ul |
0.03 |
0.08 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
81884 |
1498 |
| DDI/Ddia |
prothrombin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70.0 days
| 6 |
|
15.5 |
s |
0.08 |
0.2 |
automated coagulometer method |
|
|
Sysmex, CA-3000 type |
|
81892 |
1498 |
| DDI/Ddia |
plasma albumin to plasma total protein ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70.0 days
| 6 |
|
1.41 |
null |
0.03 |
0.07 |
automated plasma protein analysis |
|
|
Hitachi, model 7170 |
plasma albumin to plasma total protein ratio |
81899 |
1498 |
| DDI/Ddia |
total plasma calcium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood calcium amount |
male |
70.0 days
| 6 |
|
9.5 |
mg/dl |
0.08 |
0.2 |
automated blood electrolyte analysis |
|
|
Hitachi, model 7170 |
|
81909 |
1498 |
| DDI/Ddia |
blood segmented neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70.0 days
| 6 |
|
18.0 |
% |
2.45 |
6.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
segmented neutrophil % |
81916 |
1498 |
| DDI/Ddia |
spleen weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70.0 days
| 6 |
|
0.26 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
73770 |
41 |
| DDI/Ddia |
urine sodium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63.0 days
| 6 |
|
27.0 |
mmol/l |
8.98 |
22.0 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95990 |
1662 |