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Strain
Phenotype
Conditions
Study
Experiment Name
Sex
Age
# of Animals
Value
Units
SEM
SD
Method
Method Duration
Post Insult Type
Post Insult Time Value
Post Insult Time Unit
Method Notes
Clinical Measurement Notes
Record ID
Study ID
RCS-p+/LavRrrc
retinal inner layer thickness
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug)
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13.
retinal inner nuclear layer morphology trait
both
70.0 days
4
32.2
um
1.6
3.2
ex vivo light microscopy with histochemistry and digital image analysis
0.0
plasmid delivery
54
days
pVAX2-rGDNF
superior hemisphere
108738
3131
RCS-p+/LavRrrc
retinal inner layer thickness
sham gene transfer using an empty plasmid vector pVAX2 (30 ug)
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13.
retinal inner nuclear layer morphology trait
both
70.0 days
5
20.1
um
0.6
1.34
ex vivo light microscopy with histochemistry and digital image analysis
0.0
plasmid delivery
54
days
superior hemisphere
108714
3131
RCS-p+/LavRrrc
retinal inner layer thickness
sham gene transfer using an empty plasmid vector pVAX2 (30 ug) and sham gene transfer using an empty plasmid vector pVAX2 (30 ug)
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13.
retinal inner nuclear layer morphology trait
both
70.0 days
4
30.5
um
1.3
2.6
ex vivo light microscopy with histochemistry and digital image analysis
0.0
plasmid delivery
54
days
superior hemisphere
108737
3131
RCS-p+/LavRrrc
retinal inner layer thickness
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug)
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13.
retinal inner nuclear layer morphology trait
both
70.0 days
5
27.4
um
0.6
1.34
ex vivo light microscopy with histochemistry and digital image analysis
0.0
plasmid delivery
54
days
pVAX2-rGDNF
superior hemisphere
108713
3131
RCS-p+/LavRrrc
retinal inner layer thickness
sham gene transfer using an empty plasmid vector pVAX2 (30 ug)
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13.
retinal inner nuclear layer morphology trait
both
87.0 days
5
20.8
um
0.9
2.01
ex vivo light microscopy with histochemistry and digital image analysis
0.0
plasmid delivery
71
days
superior hemisphere
108720
3131
RCS-p+/LavRrrc
retinal inner layer thickness
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug)
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13.
retinal inner nuclear layer morphology trait
both
87.0 days
5
21.4
um
0.7
1.57
ex vivo light microscopy with histochemistry and digital image analysis
0.0
plasmid delivery
71
days
pVAX2-rGDNF
superior hemisphere
108719
3131
RCS-p+/LavRrrc
retinal inner layer thickness
gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug)
Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13.
retinal inner nuclear layer morphology trait
both
70.0 days
4
28.3
um
1.3
2.6
ex vivo light microscopy with histochemistry and digital image analysis
0.0
plasmid delivery
54
days
pVAX2-rGDNF
superior hemisphere
108739
3131