| LEA/Hkm |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
42.0 days
| 6 |
|
144.0 |
g |
8.33 |
20.4 |
whole body digital scale |
|
|
|
|
70790 |
21 |
| LEA/Hkm |
brain weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70.0 days
| 6 |
|
0.74 |
% |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72120 |
41 |
| LEA/Hkm |
blood hemoglobin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
16.5 |
g/dl |
0.12 |
0.3 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78136 |
1498 |
| LEA/Hkm |
hematocrit |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70.0 days
| 6 |
|
52.6 |
% |
3.39 |
8.3 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78137 |
1498 |
| LEA/Hkm |
platelet count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
platelet quantity |
male |
70.0 days
| 6 |
|
1006.0 |
x 1000 /ul |
16.74 |
41.0 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78142 |
1498 |
| LEA/Hkm |
plasma alanine aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alanine transaminase amount |
male |
70.0 days
| 6 |
|
34.0 |
U/l |
1.63 |
4.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78146 |
1498 |
| LEA/Hkm |
plasma alkaline phosphatase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alkaline phosphatase amount |
male |
70.0 days
| 6 |
|
426.0 |
IU/l |
16.33 |
40.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78147 |
1498 |
| LEA/Hkm |
plasma glucose level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood glucose amount |
male |
70.0 days
| 6 |
|
117.0 |
mg/dl |
2.45 |
6.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78151 |
1498 |
| LEA/Hkm |
plasma phosphate level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood phosphate amount |
male |
70.0 days
| 6 |
|
7.7 |
mg/dl |
0.16 |
0.4 |
automated blood electrolyte analysis |
|
|
Hitachi, model 7170 |
|
78159 |
1498 |
| LEA/Hkm |
blood eosinophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
eosinophil quantity |
male |
70.0 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
78165 |
1498 |
| LEA/Hkm |
urine sodium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63.0 days
| 6 |
|
141.4 |
mmol/l |
6.04 |
14.8 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95150 |
1662 |
| LEA/Hkm |
urine sodium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63.0 days
| 6 |
|
0.01 |
uEq/min/g |
0.0 |
0.0 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95151 |
1662 |
| LEA/Hkm |
body temperature |
specific pathogen-free condition |
NBRP Body Temperature data |
body temperature trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
38.5 |
degrees C |
0.24 |
0.6 |
digital rectal thermometry |
|
|
|
|
75044 |
22 |
| LEA/Hkm |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
35.0 days
| 6 |
|
107.4 |
g |
7.8 |
19.1 |
whole body digital scale |
|
|
|
|
70788 |
21 |
| LEA/Hkm |
brain wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70.0 days
| 6 |
|
1.98 |
g |
0.06 |
0.14 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72119 |
41 |
| LEA/Hkm |
lung weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70.0 days
| 6 |
|
0.44 |
% |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72124 |
41 |
| LEA/Hkm |
spleen wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70.0 days
| 6 |
|
0.55 |
g |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72131 |
41 |
| LEA/Hkm |
mean corpuscular hemoglobin |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
20.9 |
pg |
0.12 |
0.3 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78139 |
1498 |
| LEA/Hkm |
plasma triglyceride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood triglyceride amount |
male |
70.0 days
| 6 |
|
0.25 |
mmol/l |
0.04 |
0.09 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78155 |
1498 |
| LEA/Hkm |
plasma urea nitrogen level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood urea nitrogen amount |
male |
70.0 days
| 6 |
|
4.78 |
mmol/l |
0.31 |
0.75 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78157 |
1498 |
| LEA/Hkm |
total plasma calcium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood calcium amount |
male |
70.0 days
| 6 |
|
10.0 |
mg/dl |
0.04 |
0.1 |
automated blood electrolyte analysis |
|
|
Hitachi, model 7170 |
|
78160 |
1498 |
| LEA/Hkm |
plasma chloride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood chloride amount |
male |
70.0 days
| 6 |
|
105.0 |
mmol/l |
0.41 |
1.0 |
automated blood electrolyte analysis |
|
|
Analytical intruments, PVA alpha II |
|
78163 |
1498 |
| LEA/Hkm |
blood segmented neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70.0 days
| 6 |
|
11.0 |
% |
2.45 |
6.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
segmented neutrophil % |
78167 |
1498 |
| LEA/Hkm |
blood monocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
monocyte quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
78169 |
1498 |
| LEA/Hkm |
urine potassium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63.0 days
| 6 |
|
76.9 |
mmol/l |
11.55 |
28.3 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95152 |
1662 |
| LEA/Hkm |
heart rate |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
heart pumping trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
445.0 |
beats/min |
6.94 |
17.0 |
tail cuff photoplethysmography |
|
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75043 |
14 |
| LEA/Hkm |
heart wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70.0 days
| 6 |
|
0.87 |
g |
0.05 |
0.12 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72121 |
41 |
| LEA/Hkm |
liver wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70.0 days
| 6 |
|
6.67 |
g |
0.48 |
1.17 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72125 |
41 |
| LEA/Hkm |
mean corpuscular volume |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte size trait |
male |
70.0 days
| 6 |
|
66.7 |
fl |
4.2 |
10.3 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78138 |
1498 |
| LEA/Hkm |
prothrombin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70.0 days
| 6 |
|
16.3 |
s |
0.12 |
0.3 |
automated coagulometer method |
|
|
Sysmex, CA-3000 type |
|
78143 |
1498 |
| LEA/Hkm |
plasma total cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood cholesterol amount |
male |
70.0 days
| 6 |
|
77.0 |
mg/dl |
2.45 |
6.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78152 |
1498 |
| LEA/Hkm |
non-specified leukocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
unidentified differential wbc |
78170 |
1498 |
| LEA/Hkm |
timed urine volume to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63.0 days
| 6 |
|
0.06 |
ul/min/g |
0.01 |
0.02 |
metabolic cage urine volume measurement method |
|
|
|
|
95149 |
1662 |
| LEA/Hkm |
timed urine volume |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63.0 days
| 6 |
|
26.2 |
ml/d |
3.72 |
9.12 |
metabolic cage urine volume measurement method |
|
|
|
|
95148 |
1662 |
| LEA/Hkm |
urine chloride excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63.0 days
| 6 |
|
355.0 |
uEq/100g/6 hrs |
35.11 |
86.0 |
automated urine analysis |
|
|
|
|
95155 |
1662 |
| LEA/Hkm |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
70.0 days
| 6 |
|
281.2 |
g |
14.45 |
35.4 |
whole body digital scale |
|
|
|
|
70789 |
21 |
| LEA/Hkm |
lung wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70.0 days
| 6 |
|
1.19 |
g |
0.03 |
0.08 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72123 |
41 |
| LEA/Hkm |
heart weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70.0 days
| 6 |
|
3.23 |
g/kg |
0.05 |
0.12 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72122 |
41 |
| LEA/Hkm |
both kidneys wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70.0 days
| 6 |
|
1.97 |
g |
0.12 |
0.3 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72127 |
41 |
| LEA/Hkm |
both kidneys wet weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70.0 days
| 6 |
|
0.73 |
% |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72128 |
41 |
| LEA/Hkm |
spleen weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70.0 days
| 6 |
|
0.2 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72132 |
41 |
| LEA/Hkm |
plasma aspartate aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood aspartate transaminase amount |
male |
70.0 days
| 6 |
|
120.0 |
U/l |
1.63 |
4.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78145 |
1498 |
| LEA/Hkm |
plasma albumin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70.0 days
| 6 |
|
0.4 |
g/l |
0.01 |
0.02 |
automated plasma albumin analysis |
|
|
Hitachi, model 7170 |
|
78149 |
1498 |
| LEA/Hkm |
plasma albumin to plasma total protein ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70.0 days
| 6 |
|
2.21 |
null |
0.15 |
0.36 |
automated plasma protein analysis |
|
|
Hitachi, model 7170 |
plasma albumin to plasma total protein ratio |
78150 |
1498 |
| LEA/Hkm |
plasma low density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood LDL cholesterol amount |
male |
70.0 days
| 6 |
|
15.0 |
mg/dl |
0.82 |
2.0 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78154 |
1498 |
| LEA/Hkm |
blood band neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
band neutrophil % |
78166 |
1498 |
| LEA/Hkm |
blood basophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
basophil quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
78164 |
1498 |
| LEA/Hkm |
liver weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70.0 days
| 6 |
|
2.46 |
% |
0.05 |
0.11 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72126 |
41 |
| LEA/Hkm |
both adrenal glands wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70.0 days
| 6 |
|
39.8 |
mg |
1.43 |
3.5 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72129 |
41 |
| LEA/Hkm |
both testes wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70.0 days
| 6 |
|
2.95 |
g |
0.18 |
0.44 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72133 |
41 |
| LEA/Hkm |
both adrenal glands weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70.0 days
| 6 |
|
14.9 |
mg/100g |
0.73 |
1.8 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72130 |
41 |
| LEA/Hkm |
both testes wet weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70.0 days
| 6 |
|
1.12 |
% |
0.09 |
0.23 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
72134 |
41 |
| LEA/Hkm |
red blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70.0 days
| 6 |
|
7.89 |
x 10E6 cells/ul |
0.06 |
0.15 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78135 |
1498 |
| LEA/Hkm |
white blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70.0 days
| 6 |
|
5.1 |
x 1000 cells/ul |
0.53 |
1.3 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78141 |
1498 |
| LEA/Hkm |
activated partial thromboplastin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70.0 days
| 6 |
|
14.0 |
s |
0.49 |
1.2 |
automated coagulometer method |
|
|
Sysmex, CA-3000 type |
|
78144 |
1498 |
| LEA/Hkm |
mean corpuscular hemoglobin concentration |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
31.8 |
g/dl |
1.67 |
4.1 |
automated cell/particle size/count analysis method |
|
|
Sysmex, F-800 type |
|
78140 |
1498 |
| LEA/Hkm |
plasma total protein level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood total protein amount |
male |
70.0 days
| 6 |
|
59.0 |
mg/ml |
0.41 |
1.0 |
automated plasma total protein analysis |
|
|
Hitachi, model 7170 |
|
78148 |
1498 |
| LEA/Hkm |
plasma high density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood HDL cholesterol amount |
male |
70.0 days
| 6 |
|
49.3 |
mg/dl |
1.67 |
4.1 |
automated plasma analysis |
|
|
PMID:15591307 |
|
78153 |
1498 |
| LEA/Hkm |
plasma total bilirubin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood bilirubin amount |
male |
70.0 days
| 6 |
|
0.08 |
mg/dl |
0.01 |
0.02 |
automated plasma analysis |
|
|
PMID:15591307 |
total plasma bilirubin level |
78156 |
1498 |
| LEA/Hkm |
plasma creatinine level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood creatinine amount |
male |
70.0 days
| 6 |
|
0.24 |
mg/dl |
0.01 |
0.02 |
automated plasma creatinine analysis |
|
|
Hitachi, model 7170 |
|
78158 |
1498 |
| LEA/Hkm |
plasma sodium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood sodium amount |
male |
70.0 days
| 6 |
|
146.4 |
mmol/l |
0.41 |
1.0 |
automated blood electrolyte analysis |
|
|
Analytical intruments, PVA alpha II |
|
78161 |
1498 |
| LEA/Hkm |
plasma potassium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood potassium amount |
male |
70.0 days
| 6 |
|
3.83 |
mmol/l |
0.05 |
0.12 |
automated blood electrolyte analysis |
|
|
Analytical intruments, PVA alpha II |
|
78162 |
1498 |
| LEA/Hkm |
blood lymphocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
lymphocyte quantity |
male |
70.0 days
| 6 |
|
88.0 |
% |
2.45 |
6.0 |
automated differential white blood cell count test |
|
|
May-Giemsa staining |
|
78168 |
1498 |
| LEA/Hkm |
urine potassium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63.0 days
| 6 |
|
164.0 |
uEq/100g/6 hrs |
13.88 |
34.0 |
automated urine analysis |
|
|
Analytical intruments, PVA alpha II |
|
95153 |
1662 |
| LEA/Hkm |
urine chloride level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63.0 days
| 6 |
|
157.0 |
mEq/L |
4.9 |
12.0 |
automated urine analysis |
|
|
|
|
95154 |
1662 |
| LEA/Hkm |
systolic blood pressure |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
arterial blood pressure trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
120.0 |
mmHg |
2.45 |
6.0 |
tail cuff photoplethysmography |
|
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
75042 |
14 |