WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 16 |
45.5 |
ml/d |
5.04 |
20.16 |
metabolic cage urine volume measurement method |
0.0 |
unx |
168 |
days |
100003 |
2378 |
WKY |
urine total protein excretion rate |
puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
total urine protein amount |
male |
0 days
| 12 |
13.0 |
mg/d |
1.0 |
3.46 |
metabolic cage urine volume measurement method |
0.0 |
PA IV 50mg/kg |
0 |
|
100401 |
2479 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 11 |
11.66 |
ml/d |
1.01 |
3.34 |
metabolic cage urine volume measurement method |
0.0 |
unx |
168 |
days |
100000 |
2378 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 8 |
23.47 |
ml/d |
1.73 |
4.89 |
metabolic cage urine volume measurement method |
0.0 |
unx |
28 |
days |
99966 |
2378 |
WKY |
urine total protein excretion rate |
puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
total urine protein amount |
male |
0 days
| 11 |
112.0 |
mg/d |
17.0 |
56.38 |
metabolic cage urine volume measurement method |
0.0 |
PA IV 50mg/kg |
15 |
days |
100398 |
2479 |
WKY |
urine total protein excretion rate |
0.9% sodium chloride solution (3 ml) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
total urine protein amount |
male |
0 days
| 11 |
8.0 |
mg/d |
1.0 |
3.32 |
metabolic cage urine volume measurement method |
0.0 |
|
0 |
|
100400 |
2479 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 16 |
49.25 |
ml/d |
5.18 |
20.74 |
metabolic cage urine volume measurement method |
0.0 |
unx |
168 |
days |
100004 |
2378 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 6 |
44.93 |
ml/d |
8.78 |
21.52 |
metabolic cage urine volume measurement method |
0.0 |
unx |
28 |
days |
99969 |
2378 |
WKY |
urine total protein excretion rate |
controlled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
total urine protein amount |
male |
0 days
| 10 |
115.0 |
mg/d |
10.0 |
31.62 |
metabolic cage urine volume measurement method |
0.0 |
PA IV 50mg/kg |
15 |
days |
100399 |
2479 |
WKY |
urine total protein excretion rate |
controlled enalapril content drinking water (50 mg/l) (between 63 and 77 days) then puromycin aminonucleoside (50 mg/kg) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
total urine protein amount |
male |
0 days
| 12 |
10.0 |
mg/d |
1.0 |
3.46 |
metabolic cage urine volume measurement method |
0.0 |
PA IV 50mg/kg |
0 |
|
100402 |
2479 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 17 |
41.47 |
ml/d |
4.46 |
18.41 |
metabolic cage urine volume measurement method |
0.0 |
unx |
168 |
days |
100002 |
2378 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 8 |
41.62 |
ml/d |
9.07 |
25.66 |
metabolic cage urine volume measurement method |
0.0 |
unx |
28 |
days |
99968 |
2378 |
WKY |
urine total protein excretion rate |
0.9% sodium chloride solution (3 ml) |
Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. |
total urine protein amount |
male |
0 days
| 10 |
5.0 |
mg/d |
1.0 |
3.16 |
metabolic cage urine volume measurement method |
0.0 |
|
0 |
|
100397 |
2479 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 17 |
39.46 |
ml/d |
4.61 |
19.0 |
metabolic cage urine volume measurement method |
0.0 |
unx |
168 |
days |
100001 |
2378 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then vehicle control condition |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 7 |
12.38 |
ml/d |
2.02 |
5.33 |
metabolic cage urine volume measurement method |
0.0 |
unx |
28 |
days |
99965 |
2378 |
WKY |
timed urine volume |
unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) |
Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. |
urine output |
male |
0 days
| 8 |
38.02 |
ml/d |
5.33 |
15.07 |
metabolic cage urine volume measurement method |
0.0 |
unx |
28 |
days |
99967 |
2378 |