Phenominer Database Results (888 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Sample Notes Experiment Notes Record ID Study ID
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 216.0 mmHg 5.1 22.81 tail cuff plethysmography 0 average of 4days 65480 611
SS.LEW-(D1Rat211-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 179.0 mmHg 2.9 12.97 tail cuff plethysmography 0 average of 4days 65490 611
SS.LEW-(D1Mco75-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 193.0 mmHg 4.2 18.78 tail cuff plethysmography 0 average of 4days 65492 611
SS.LEW-(D1Mco102-D1Mco129)/1Mco systolic blood pressure controlled sodium content diet (0.4 %) (between 36 and 40 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 66.0 days-70.0 days 20 serial mean 172.0 mmHg 1.9 8.5 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65310 565
WKY mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 112.0 days 28 continuous mean 120.6 mmHg 1.34 7.1 tail cuff plethysmography 0 animals were prewarmed to 34 degrees C for 20 min before BP 65080 206
WKY mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 140.0 days 28 continuous mean 126.0 mmHg 1.38 7.3 tail cuff plethysmography 0 animals were prewarmed to 34 degrees C for 20 min before BP 65084 206
SS.SR-Inha/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6 arterial blood pressure trait male 62.0 days 20 176.0 mmHg 2.6 11.63 tail cuff plethysmography 0 only mentioned blood pressure 65830 633
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) (for 21 days) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -28.0 mmHg 4.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67262 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (for 21 days) then ruthenium red (3 mg/kg) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -23.0 mmHg 3.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67268 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (for 21 days) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -27.0 mmHg 1.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67264 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 7.0 mmHg 1.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67271 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then apamin (100 ug/kg) and charybdotoxin (100 ug/kg) and 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -10.0 mmHg 1.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67273 731
SS/Jr systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 56.0 days-57.0 days 6 serial mean 168.0 mmHg 5.1 12.49 tail cuff plethysmography tail between 7 am and 12 pm 11584 104
SS/Jr systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 182.0 days-183.0 days 6 serial mean 208.0 mmHg 4.6 11.27 tail cuff plethysmography tail 2 days between 7 am and 12 pm 11596 104
SHRSP.WKY-(Klk1-D1Rat116)/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait male 91.0 days 5 181.8 mmHg 5.1 11.4 tail cuff plethysmography 11680 115
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 100.0 days 16 serial mean 200.3 mmHg 6.0 24.0 tail cuff plethysmography 11782 146
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 42 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 79.0 days 20 serial mean 198.1 mmHg 5.7 25.49 tail cuff plethysmography 11790 146
SS.SR-(D7Rat16-D7Rat189)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 219.0 mmHg 3.4 15.21 tail cuff plethysmography average of 12 readings from 4 daily sessions 11802 147
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 232.7 mmHg 3.2 14.31 tail cuff plethysmography average of 12 readings from 4 daily sessions 11819 147
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 19 serial mean 221.8 mmHg 2.9 12.64 tail cuff plethysmography average of 12 readings from 4 daily sessions 11825 147
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 18 serial mean 217.0 mmHg 4.0 16.97 tail cuff plethysmography average of 12 readings from 4 daily sessions 11831 148
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 195.0 mmHg 3.35 14.98 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12129 232
SS.MNS-(D10Mco62-D10Got99)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 197.0 mmHg 3.04 13.6 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12134 232
SS.MNS-(D10Mco30-D10Got91)/2Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 201.0 mmHg 2.71 12.12 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12139 232
SS.MNS-(D10Mco30-D10Got91)/1Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 206.0 mmHg 5.06 22.63 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12138 232
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 8 serial mean 142.0 mmHg 2.6 7.35 tail cuff plethysmography tail 0 12177 222
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 204.0 mmHg 3.72 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11911 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 221.0 mmHg 3.95 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11913 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 194.0 mmHg 3.38 15.12 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12808 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 30 198.0 mmHg 1.78 9.75 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12810 313
SS.LEW-(D1Mco36-D1Rat131)/2Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 170.0 mmHg 2.33 10.42 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12818 313
SS.LEW-(D1Mco36-D1Mco101)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 30 173.0 mmHg 1.36 7.45 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12821 313
SS.LEW-(D1Mco36-D1Rat106)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 30 173.0 mmHg 1.74 9.53 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12820 313
SS.LEW-(D1Mco85-D1Rat49)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 196.0 mmHg 1.93 8.63 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12822 313
SS.LEW-(D1Mco38-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 181.0 mmHg 3.03 13.55 tail cuff plethysmography average of 3-4 consistent readings 12464 266
SS.LEW-(D1Mco87-D1Rat71)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 207.0 mmHg 2.87 12.84 tail cuff plethysmography average of 3-4 consistent readings 12461 266
SS.LEW-(D1Uia2-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 187.0 mmHg 2.42 10.82 tail cuff plethysmography average of 3-4 consistent readings 12465 266
SS.LEW-(D1Rat196-D1Mco36)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 183.0 mmHg 2.25 10.06 tail cuff plethysmography average of 3-4 consistent readings 12469 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 194.0 mmHg 7.36 tail cuff plethysmography 0.0 67509 749
SS.SHR-(D9Mco72-D9Rat55)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 188.0 mmHg 3.67 tail cuff plethysmography 0.0 67512 749
SS.LEW-(D10Mit10-D10Mgh1)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 20 serial mean 177.0 mmHg 2.1 9.39 tail cuff plethysmography tail 0 64740 222
SS/Jr systolic blood pressure controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 131.0 days-134.0 days 21 data obtained at three consistent sessions per day serial mean 244.0 mmHg tail cuff plethysmography 345600 65963 650
SS.SR-(D13N1-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait not specified 65.0 days-68.0 days 26 data obtained at three consistent sessions per day serial mean 217.0 mmHg tail cuff plethysmography 345600 66029 650
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -6.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67240 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -5.0 mmHg 3.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67239 731
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 18 139.0 mmHg 1.65 7.0 tail cuff plethysmography 0.0 69126 1126
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 18 185.0 mmHg 1.72 7.3 tail cuff plethysmography 0.0 69127 1126
WAG/RijKyo systolic blood pressure control condition Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. arterial blood pressure trait not specified 180.0 days 9 135.0 mmHg 3.4 10.2 tail cuff plethysmography 0.0 68049 835
SHRSP.WKY-(D1Smu13-D1Arb21)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 13 serial mean 179.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements 68739 990
SHRSP.WKY-(Apbb1-D1Arb21)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 14 serial mean 187.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements 68740 990
WAG/RijKyo systolic blood pressure physical restraint in mechanical restrainer (for 0.5 hours) Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. arterial blood pressure trait not specified 180.0 days 9 140.0 mmHg 5.1 15.3 tail cuff plethysmography 0.0 68064 835
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm systolic blood pressure cold ambient air exposure (4 degrees C) (for 90 days) Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. arterial blood pressure trait not specified 112.0 days 10 157.0 mmHg 1.39 4.4 tail cuff plethysmography 0.0 10 s every 5 min 68691 971
SHRSP/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 151.0 mmHg 1.44 8.0 tail cuff plethysmography 0.0 69162 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 31 176.0 mmHg 1.89 10.5 tail cuff plethysmography 0.0 69174 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 29 202.0 mmHg 1.67 9.0 tail cuff plethysmography 0.0 69170 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 31 197.0 mmHg 1.8 10.0 tail cuff plethysmography 0.0 69176 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 31 181.0 mmHg 1.65 9.2 tail cuff plethysmography 0.0 69175 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 25 201.0 mmHg 1.4 7.0 tail cuff plethysmography 0.0 69185 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 31 166.0 mmHg 1.96 10.9 tail cuff plethysmography 0.0 69181 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 33 114.0 mmHg 0.17 1.0 tail cuff plethysmography 0.0 69186 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 33 164.0 mmHg 2.61 15.0 tail cuff plethysmography 0.0 69187 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 3 195.0 mmHg 2.89 5.0 tail cuff plethysmography 0.0 69190 1126
SHRSP.SHRSR-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 153.0 mmHg 2.16 12.0 tail cuff plethysmography 0.0 69192 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 35 112.0 mmHg 0.68 4.0 tail cuff plethysmography 0.0 69195 1126
SHRSP.SHRSR-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 22 200.0 mmHg 0.85 4.0 tail cuff plethysmography 0.0 69194 1126
SS.LEW-(D5Mco39-D5Mco57)/2Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 221.0 mmHg 6.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70589 1482
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 196.0 mmHg 6.8 tail cuff plethysmography 0.0 restrained, 28 degrees C 70583 1482
Crl:SD systolic blood pressure controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. arterial blood pressure trait male 63.0 days-77.0 days 8 142.0 mmHg 3.0 8.49 tail cuff plethysmography tail 0.0 CT 75854 1540
SHRSP/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 18 serial mean 213.0 mmHg 3.77 16.0 tail cuff plethysmography 0.0 avg of 5 measurements for 84620 990
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 198.0 mmHg 8.0 43.82 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96920 1778
SS.LEW-(D1Mco36-D1Rat200)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 226.0 mmHg 4.0 21.91 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96941 1778
SS.LEW-(D1Mco55-D1Wox6)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 157.0 mmHg 6.0 32.86 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96944 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 198.0 mmHg 8.0 43.82 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96980 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 208.0 mmHg 6.0 32.86 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96982 1778
SHR/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 18 undefined 180.0 mmHg 0.94 4.0 tail cuff plethysmography 0.0 97911 1938
SHR/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 18 undefined 188.0 mmHg 0.94 4.0 tail cuff plethysmography 0.0 97913 1938
SHR-Ndufc2em1Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 10 undefined 177.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 97916 1938
SHRSP/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 49 days) and controlled potassium content diet (6.3 mg/g) (for 49 days) and controlled sodium content diet (3.7 mg/g) (for 49 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 91.0 days 5 undefined 193.0 mmHg 6.26 14.0 tail cuff plethysmography 0.0 97915 1938
SHR-Ndufc2em1Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 17 undefined 178.0 mmHg 1.46 6.0 tail cuff plethysmography 0.0 97920 1938
SHR-Ndufc2em1Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 17 undefined 174.0 mmHg 1.46 6.0 tail cuff plethysmography 0.0 97919 1938
SHR-Ndufc2em2Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 12 undefined 190.0 mmHg 0.87 3.0 tail cuff plethysmography 0.0 97924 1938
SHR-Ndufc2em2Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 12 undefined 181.0 mmHg 2.6 9.0 tail cuff plethysmography 0.0 97923 1938
LH/Mav systolic blood pressure perindopril (1.5 mg/kg/d) (for 42 days) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. arterial blood pressure trait male 63.0 days 7 undefined 113.0 mmHg 3.0 7.94 tail cuff plethysmography 0.0 102850 2761
SS heart rate controlled sodium content diet (0.3 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart pumping trait male 42.0 days 5 438.0 beats/min 5.37 12.0 tail cuff plethysmography 0.0 103278 2803
SR heart rate controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart pumping trait male 126.0 days 6 375.0 beats/min 11.02 27.0 tail cuff plethysmography 0.0 103283 2803
WKY systolic blood pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 5 119.0 mmHg 3.0 6.71 tail cuff plethysmography 0.0 PA IV 50mg/kg 100592 2479
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (400 ng/hr) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77.0 days 14 332.0 beats/min 9.35 35.0 tail cuff plethysmography 0.0 102458 2689
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77.0 days 14 355.0 beats/min 10.16 38.0 tail cuff plethysmography 0.0 102457 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 77.0 days 10 undefined 140.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 102492 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126.0 days 10 415.0 beats/min 8.85 28.0 tail cuff plethysmography 0.0 102497 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126.0 days 10 383.0 beats/min 15.18 48.0 tail cuff plethysmography 0.0 102505 2690
LH/Mav systolic blood pressure vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 112.0 days 11 mean of 3 samples of undefined duration serial mean 160.0 mmHg 4.0 13.27 tail cuff plethysmography 0.0 102728 2721
WKY systolic blood pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 5 127.0 mmHg 5.0 11.18 tail cuff plethysmography 0.0 PA IV 50mg/kg 100594 2479
WKY systolic blood pressure 0.9% sodium chloride solution (50 mg/kg) (for 0.5 hours) then 0.9% sodium chloride solution Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 5 131.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 PA IV 50mg/kg 100595 2479
LH/Mav systolic blood pressure control condition (between 147 and 154 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 84.0 days 12 between 9a-1p 152.0 mmHg 3.0 10.39 tail cuff plethysmography 0.0 103432 2825
LH/Mav systolic blood pressure controlled perindopril content drinking water (0.4 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 84.0 days 13 between 9a-1p 122.0 mmHg 2.0 7.21 tail cuff plethysmography 0.0 103434 2825
SD-Tg(Ren2)27-/- systolic blood pressure control condition (for 0 hours) Cerutti C, et al., Physiol Genomics. 2006 Nov 27;27(3):295-308. doi: 10.1152/physiolgenomics.00318.2005. Epub 2006 Aug 1. arterial blood pressure trait male 84.0 days 6 129.0 mmHg 3.0 7.35 tail cuff plethysmography 0.0 103468 2826
WKY systolic blood pressure control condition (for 0 hours) Cerutti C, et al., Physiol Genomics. 2006 Nov 27;27(3):295-308. doi: 10.1152/physiolgenomics.00318.2005. Epub 2006 Aug 1. arterial blood pressure trait male 84.0 days 5 125.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 103470 2826
WF/Mol systolic blood pressure vehicle control condition then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 103.0 mmHg 6.0 14.7 tail cuff plethysmography 0.0 acf 4 days 101346 2585
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 377.0 beats/min 11.0 26.94 tail cuff plethysmography 0.0 sham acf 2 days 101379 2585
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 8 469.0 beats/min 10.0 28.28 tail cuff plethysmography 0.0 acf 4 days 101380 2585
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 410.0 beats/min 8.0 19.6 tail cuff plethysmography 0.0 sham acf 4 days 101381 2585
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 424.0 beats/min 10.0 22.36 tail cuff plethysmography 0.0 sham acf 2 days 101377 2585
MW systolic blood pressure right nephrectomy (for 84 days) then reserpine (5 mg/l) (for 28 days) and hydralazine (80 mg/l) (for 28 days) and controlled hydralazine content drinking water (25 mg/l) (for 28 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 131.1 mmHg 4.0 12.65 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 84 days 100870 2523
MW systolic blood pressure right nephrectomy (for 112 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 6 undefined 180.8 mmHg 8.5 20.82 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 112 days 100876 2523
SR/Hsd mean arterial blood pressure controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 91.0 days 8 114.0 mmHg 2.12 6.0 tail cuff plethysmography 0.0 102269 2683
MW systolic blood pressure unilateral nephrectomy (for 14 days) then puromycin aminonucleoside (100 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 6 undefined 122.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 unx 14 days 101158 2581
MW systolic blood pressure unilateral nephrectomy (for 14 days) then vehicle control condition Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 7 undefined 118.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 unx 42 days 101163 2581
MW systolic blood pressure unilateral nephrectomy (for 42 days) then puromycin aminonucleoside (100 mg/kg) then puromycin aminonucleoside (40 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 6 undefined 125.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 unx 42 days 101162 2581
SD systolic blood pressure unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 5 undefined 125.0 mmHg 6.26 14.0 tail cuff plethysmography 0.0 unx 13 days 101549 2602
SD systolic blood pressure sham surgical control condition (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 6 undefined 118.0 mmHg 4.08 10.0 tail cuff plethysmography 0.0 sham unx 28 days 101583 2602
SD systolic blood pressure unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 7 undefined 109.0 mmHg 4.16 11.0 tail cuff plethysmography 0.0 unx 28 days 101585 2602
SD systolic blood pressure unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 8 undefined 190.0 mmHg 9.9 28.0 tail cuff plethysmography 0.0 unx 28 days 101618 2602
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 123.0 mmHg 5.0 11.18 tail cuff plethysmography 0.0 sham acf 4 days 101347 2585
WF/Mol systolic blood pressure controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 7 undefined 101.0 mmHg 5.0 13.23 tail cuff plethysmography 0.0 acf 7 days 101348 2585
WF/Mol heart rate controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 366.0 beats/min 14.0 31.3 tail cuff plethysmography 0.0 sham acf 4 days 101367 2585
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 165.0 mmHg 7.0 15.65 tail cuff plethysmography 0.0 sham acf 7 days 101365 2585
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 358.0 beats/min 12.0 26.83 tail cuff plethysmography 0.0 sham acf 7 days 101373 2585
WF/Mol heart rate controlled ramipril content drinking water (3 mg/kg/d) (for 10 days) then artificial aortocaval fistula (for 9 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 7 473.0 beats/min 20.0 52.92 tail cuff plethysmography 0.0 acf 9 days 101374 2585
LL/Mav systolic blood pressure vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 56.0 days 9 mean of 3 samples of undefined duration serial mean 115.0 mmHg 5.0 15.0 tail cuff plethysmography 0.0 102702 2721
LH/Mav systolic blood pressure vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 56.0 days 11 mean of 3 samples of undefined duration serial mean 134.0 mmHg 4.0 13.27 tail cuff plethysmography 0.0 102704 2721
LH/Mav systolic blood pressure streptozotocin (75 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 56.0 days 14 mean of 3 samples of undefined duration serial mean 148.0 mmHg 4.0 14.97 tail cuff plethysmography 0.0 102705 2721
SS-Nppbem2Mcwi-/- diastolic blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168.0 days 7 serial mean 142.0 mmHg 28.0 74.08 tail cuff plethysmography 0.0 99824 2319
SS-Nppbem2Mcwi-/- mean arterial blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 252.0 days 7 serial mean 162.0 mmHg 29.0 76.73 tail cuff plethysmography 0.0 99838 2319
LH/Mav systolic blood pressure streptozotocin (75 mg/kg) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. arterial blood pressure trait male 49.0 days-56.0 days 37 undefined 145.0 mmHg 2.0 12.17 tail cuff plethysmography 0.0 102646 2703
SD mean arterial blood pressure left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 137.0 mmHg 10.0 26.46 tail cuff plethysmography 0.0 unx 70 days 98947 2179
WF/Mol heart rate vehicle control condition then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 448.0 beats/min 10.0 24.49 tail cuff plethysmography 0.0 acf 4 days 101382 2585
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 460.0 beats/min 5.0 12.25 tail cuff plethysmography 0.0 acf 7 days 101384 2585
SS/NEisSlc systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. arterial blood pressure trait male 126.0 days 8 undefined 226.0 mmHg 11.0 31.11 tail cuff plethysmography 0.0 102314 2684
SS/NEisSlc systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. arterial blood pressure trait male 126.0 days 8 undefined 235.0 mmHg 13.0 36.77 tail cuff plethysmography 0.0 102315 2684
SD systolic blood pressure nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 6 serial mean 142.6 mmHg 7.1 17.39 tail cuff plethysmography 0.0 unx 84 days 100118 2419
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 63.0 days 8 398.0 beats/min 13.08 37.0 tail cuff plethysmography 0.0 102412 2689
MWF/ZtmRrrc mean arterial blood pressure enalapril (50 mg/l) (for 182 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 246.0 days 6 undefined 127.0 mmHg 2.86 7.0 tail cuff plethysmography 0.0 100920 2541
WKY systolic blood pressure 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 9 106.0 mmHg 3.0 9.0 tail cuff plethysmography 0.0 100445 2479
SD systolic blood pressure left anterior descending coronary artery occlusion (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. arterial blood pressure trait male 189.0 days 10 undefined 143.0 mmHg 3.0 9.49 tail cuff plethysmography 0.0 lad occlusion 140 days 101089 2564
SS.ZUC-Leprfa+/+/Slc heart rate bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91.0 days 9 380.0 beats/min 8.0 24.0 tail cuff plethysmography 0.0 ovariectomy 42 days 101673 2622
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 120.0 days 4 mean of 3 samples - 1 per minute serial mean 146.0 mmHg 1.0 2.0 tail cuff plethysmography 0.0 100180 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure controlled enalapril content drinking water (5 mg/kg/d) (for 10 days) Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 70.0 days 4 mean of 3 samples - 1 per minute serial mean 121.0 mmHg 1.5 3.0 tail cuff plethysmography 0.0 100185 2439
SD systolic blood pressure controlled losartan content drinking water (5 mg/kg/d) (for 10 days) Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 130.0 days 1 mean of 3 samples - 1 per minute serial mean 116.0 mmHg tail cuff plethysmography 0.0 100190 2439
SD systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 120.0 days 1 mean of 3 samples - 1 per minute serial mean 119.0 mmHg tail cuff plethysmography 0.0 100189 2439
SD systolic blood pressure streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. arterial blood pressure trait male  days 8 undefined 128.0 mmHg 1.06 3.0 tail cuff plethysmography 0.0 stz 224 days 99924 2358
OLETF systolic blood pressure olmesartan medoxomil (3.8 mg/kg/d) (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 12 undefined 132.1 mmHg 3.3 11.43 tail cuff plethysmography 0.0 99423 2298
OLETF diastolic blood pressure temocapril (3.9 mg/kg/d) (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 11 undefined 100.1 mmHg 3.3 10.94 tail cuff plethysmography 0.0 99429 2298
Crl:WI systolic blood pressure control condition (for 84 days) Ruiz-Torres MP, et al., J Am Soc Nephrol. 1998 May;9(5):782-91. arterial blood pressure trait male 84.0 days 10 144.0 mmHg 5.0 15.81 tail cuff plethysmography 0.0 101282 2584
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (0.65 %) (for 98 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98.0 days 7 128.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 106698 3038
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 108.0 days-112.0 days 5 58.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 n=5-7, change between age 3months and 4 months 106734 3039
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 108.0 days-112.0 days 5 4.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 3months and 4 months 106733 3039
SBH/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 42.0 days 9 138.0 mmHg 1.0 3.0 tail cuff plethysmography 0.0 106754 3039
SBH/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) then controlled sodium content drinking water (1 %) (for 28 days) and deoxycorticosterone acetate (25 mg) (for 28 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 70.0 days 9 196.0 mmHg 2.0 6.0 tail cuff plethysmography 0.0 106755 3039
SBN/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) then controlled sodium content drinking water (1 %) (for 28 days) and deoxycorticosterone acetate (25 mg) (for 28 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 70.0 days 16 126.0 mmHg 1.0 4.0 tail cuff plethysmography 0.0 106751 3039
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (between 24 and 28 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 192.0 days-196.0 days 5 5.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 n=5-7, change between age 6 months and 7 months 106737 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 108.0 days-112.0 days 5 55.0 mmHg 7.0 15.65 tail cuff plethysmography 0.0 n=5-7, change between age 3months and 4 months 106735 3039
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (between 24 and 28 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 360.0 days-364.0 days 5 2.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 12months and 13 months 106745 3039
MWF/FubRkb heart rate finerenone (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. heart pumping trait male 112.0 days 10 353.7 beats/min 6.1 19.29 tail cuff plethysmography heart 0.0 109414 3140
SHRSP/A3NCrl systolic blood pressure control condition (for 91 days) Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. arterial blood pressure trait male 161.0 days-175.0 days 7 160.0 mmHg 5.0 13.23 tail cuff plethysmography 0.0 107386 3083
SHRSP/A3N systolic blood pressure control condition Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. arterial blood pressure trait male 120.0 days-140.0 days 24 244.0 mmHg 4.0 19.6 tail cuff plethysmography 0.0 107568 3093
MWF/ZtmRrrc mean arterial blood pressure control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 250.0 days 8 undefined 184.0 mmHg 6.01 17.0 tail cuff plethysmography 0.0 107647 2541
SHR systolic blood pressure diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 155.11 mmHg 9.41 24.89 tail cuff plethysmography 60 min 0.1% methylcellulose per os 108286 3101
SHR systolic blood pressure diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 149.29 mmHg 7.17 18.98 tail cuff plethysmography 150 min 0.1% methylcellulose per os 108292 3101
SHR systolic blood pressure proestrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 169.17 mmHg 1.16 3.06 tail cuff plethysmography 108296 3101
SHR systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 160.67 mmHg 1.11 2.94 tail cuff plethysmography 108300 3101
WAG systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 118.83 mmHg 1.65 4.36 tail cuff plethysmography 108303 3101
WAG systolic blood pressure estrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 124.14 mmHg 1.68 4.45 tail cuff plethysmography 108317 3101
SHR systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 171.86 mmHg 5.62 14.86 tail cuff plethysmography 108322 3101
SHR systolic blood pressure estrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 163.71 mmHg 2.21 5.85 tail cuff plethysmography 108318 3101
WAG systolic blood pressure diestrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 136.71 mmHg 1.77 4.68 tail cuff plethysmography 108333 3101
SHR systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 151.71 mmHg 4.22 11.16 tail cuff plethysmography 108336 3101
WAG systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 114.14 mmHg 1.6 4.22 tail cuff plethysmography 108337 3101
WAG systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 122.43 mmHg 2.95 7.81 tail cuff plethysmography 108341 3101
SHR systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 152.14 mmHg 2.52 6.67 tail cuff plethysmography 108338 3101
SHR systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 162.57 mmHg 4.24 11.22 tail cuff plethysmography 108342 3101
WKY systolic blood pressure diclofenac (20 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 122.6 mmHg 0.74 1.97 tail cuff plethysmography 60 min 0.1% methylcellulose per os 108363 3101
WAG/Nov systolic blood pressure ether (for 0.1 hours) Markel AL, et al., J Endocrinol. 2007 Dec;195(3):439-50. doi: 10.1677/JOE-07-0254. arterial blood pressure trait male 120.0 days-150.0 days 27 128.0 mmHg 3.0 15.59 tail cuff plethysmography 0.0 108636 3127
MWF/Fub systolic blood pressure standard diet Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. arterial blood pressure trait male 100.0 days-103.0 days 8 165.0 mmHg 2.0 5.66 tail cuff plethysmography tail 0.0 109021 3134
MWF systolic blood pressure control condition Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. arterial blood pressure trait male 126.0 days-140.0 days 7 150.0 mmHg 3.55 9.4 tail cuff plethysmography 0.0 110008 3163
WKY/NMolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 240.0 days 9 118.0 mmHg 4.9 14.7 tail cuff plethysmography 0.0 10 consecutive measurements 106933 3071
SHR/FubRkb systolic blood pressure control condition Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. arterial blood pressure trait male 84.0 days 10 178.0 mmHg 2.0 6.32 tail cuff plethysmography 0.0 109282 3141
MNS/Gib systolic blood pressure controlled sodium chloride content diet (2.5 g/kg) Ferrandi M, etal., Am J Physiol. 1999 Oct;277(4):H1338-49. doi: 10.1152/ajpheart.1999.277.4.H1338. arterial blood pressure trait male 91.0 days 132.0 mmHg 1.8 tail cuff plethysmography 0.0 110653 3135
SHRSP/A3N systolic blood pressure controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. arterial blood pressure trait male 203.0 days-224.0 days 10 267.0 mmHg 7.0 22.14 tail cuff plethysmography tail 0.0 high salt high fat diet 107096 3075
WKY/NCrl systolic blood pressure standard condition (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. arterial blood pressure trait male 203.0 days-224.0 days 10 179.0 mmHg 3.0 9.49 tail cuff plethysmography tail 0.0 standard rat chow 107098 3075
SHRSP/A3N systolic blood pressure controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) and controlled carvedilol content diet (2400 ppm) (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. arterial blood pressure trait male 203.0 days-224.0 days 10 260.0 mmHg 6.0 18.97 tail cuff plethysmography tail 0.0 107095 3075
WKY systolic blood pressure control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 420.0 days 4 136.0 mmHg 2.5 5.0 tail cuff plethysmography 0.0 109530 3147
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 210.0 mmHg 3.3 14.76 tail cuff plethysmography 0 average of 4days 65479 611
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 206.0 mmHg 4.2 18.78 tail cuff plethysmography 0 average of 4days 65482 611
SS.LEW-(D1Uia8-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 191.0 mmHg 2.2 9.84 tail cuff plethysmography 0 average of 4days 65484 611
SHR.WKY-(D1Rat420-D1Got161)/Njs systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 112.0 days-114.0 days 18 163.2 mmHg 0.45 1.9 tail cuff plethysmography 65251 564
SHR/NCruk systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 140.0 days-142.0 days 20 189.5 mmHg 0.38 1.7 tail cuff plethysmography 65254 564
SHR.WKY-(D1Rat420-D1Got161)/Njs systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 140.0 days-142.0 days 18 180.3 mmHg 0.38 1.6 tail cuff plethysmography 65255 564
SS.SR-(D3Mco78-D3Got130)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 209.1 mmHg 4.8 21.47 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65799 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 39 serial mean 191.8 mmHg 2.6 16.24 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65801 237
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6 arterial blood pressure trait male 62.0 days 20 195.0 mmHg 2.7 12.07 tail cuff plethysmography 0 only mentioned blood pressure 65829 633
SHR/NHsd systolic blood pressure controlled sodium content diet Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 53.0 days 10 154.0 mmHg 3.3 10.44 tail cuff plethysmography 0 66116 691
SS/Jr systolic blood pressure controlled sodium content diet (4 %) (for 14 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 67.0 days 10 218.0 mmHg 7.8 24.67 tail cuff plethysmography 0 66117 691
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 213.0 mmHg 2.5 15.81 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65790 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 218.3 mmHg 2.6 16.44 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65791 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 41 serial mean 204.7 mmHg 2.1 13.45 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65795 237
SHR/NHsd systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 56.0 days-57.0 days 6 serial mean 148.0 mmHg 4.7 11.51 tail cuff plethysmography tail between 7 am and 12 pm 11585 104
SHR/NHsd systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 140.0 days-141.0 days 6 serial mean 182.0 mmHg 6.9 16.9 tail cuff plethysmography tail 2 days between 7 am and 12 pm 11593 104
SHR/NIcoCrlf systolic blood pressure physical restraint in tube type rodent restrainer Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 arterial blood pressure trait male 70.0 days-77.0 days 12 229.0 mmHg 2.0 6.93 tail cuff plethysmography 11617 108
SHRSP/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait female 91.0 days 5 200.2 mmHg 8.7 19.45 tail cuff plethysmography 11681 115
SHRSP.WKY-(Klk1-D1Rat116)/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait female 91.0 days 5 157.0 mmHg 7.6 16.99 tail cuff plethysmography 11682 115
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 11 serial mean 200.9 mmHg 8.2 27.2 tail cuff plethysmography 11793 146
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait female 61.0 days 24 serial mean 250.1 mmHg 4.9 24.0 tail cuff plethysmography 11792 146
SS.SR-(D7Rat16-D7Mgh5)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 210.5 mmHg 2.8 12.52 tail cuff plethysmography average of 12 readings from 4 daily sessions 11796 147
SS.SR-(D7Mco7-D7Rat81)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 228.8 mmHg 2.4 10.73 tail cuff plethysmography average of 12 readings from 4 daily sessions 11808 147
SS.SR-(D7Uia1-D7Mco7)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 205.0 mmHg 1.8 8.05 tail cuff plethysmography average of 12 readings from 4 daily sessions 11814 147
SS.MNS-(D10M11Mit119-D10Mit11)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 182.0 mmHg 2.2 9.84 tail cuff plethysmography average of 12 readings from 4 daily sessions 11833 148
SS.MNS-(D10Mco30-D10Got112)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 190.0 mmHg 2.55 11.4 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12135 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 10 serial mean 142.0 mmHg 2.2 6.96 tail cuff plethysmography tail 0 12164 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 8 serial mean 141.0 mmHg 1.8 5.09 tail cuff plethysmography tail 0 12171 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 8 serial mean 140.0 mmHg 4.4 12.45 tail cuff plethysmography tail 0 12175 222
SS.LEW-(D10Mco84-D10Mco143)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 194.0 mmHg 4.18 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11917 205
SS.LEW-(D10Mco84-D10Rat58)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 236.0 mmHg 4.7 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11918 205
SS.LEW-(D1Mco36-D1Rat131)/1Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 178.0 mmHg 2.22 9.93 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12817 313
SS.LEW-(D1Mco36-D1Mco77)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 184.0 mmHg 3.07 13.73 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12819 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 202.0 mmHg 1.72 7.69 tail cuff plethysmography average of 3-4 consistent readings 12451 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 209.0 mmHg 2.97 13.28 tail cuff plethysmography average of 3-4 consistent readings 12452 266
SS.LEW-(D1Rat35-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 195.0 mmHg 2.87 12.84 tail cuff plethysmography average of 3-4 consistent readings 12462 266
SS.LEW-(D1Rat196-D1Mgh7)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 212.0 mmHg 4.63 20.71 tail cuff plethysmography average of 3-4 consistent readings 12467 266
SS.LEW-(D1Uia8-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 191.0 mmHg 2.24 10.02 tail cuff plethysmography average of 3-4 consistent readings 12471 266
SS.LEW-(D1Uia8-D1Rat213)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 169.0 mmHg 2.6 11.63 tail cuff plethysmography average of 3-4 consistent readings 12475 266
WKY/Izm systolic blood pressure controlled fat content diet (5 %) (for 63 days) and controlled potassium content diet (0.75 %) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. arterial blood pressure trait male 91.0 days 10 132.2 mmHg 2.18 6.9 tail cuff plethysmography 13277 263
SS.SHR-(D9Mco72-D9Rat89)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 183.0 mmHg 7.72 tail cuff plethysmography 0.0 67510 749
SS.SHR-(D9Mco72-D9Uia4)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 181.0 mmHg 3.91 tail cuff plethysmography 0.0 67516 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 263.0 mmHg 5.6 tail cuff plethysmography 0.0 67517 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 214.0 mmHg 5.26 tail cuff plethysmography 0.0 67515 749
SS.SHR-(D9Rat7-D9Rat52)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 203.0 mmHg 6.11 tail cuff plethysmography 0.0 67526 749
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 46 serial mean 207.0 mmHg 2.2 14.92 tail cuff plethysmography tail 0 64733 222
SS.LEW-(D5Mit9-D5Mco10)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 40 serial mean 201.0 mmHg 2.0 12.65 tail cuff plethysmography tail 0 64737 222
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 65.0 days-68.0 days 20 data obtained at three consistent sessions per day serial mean 199.0 mmHg tail cuff plethysmography 345600 65967 650
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (4 %) (between 24 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 65.0 days-68.0 days 38 data obtained at three consistent sessions per day serial mean 260.0 mmHg tail cuff plethysmography 345600 65974 650
SS/Hsd systolic blood pressure control condition Viel EC, et al., Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H938-44. Epub 2009 Dec 31. arterial blood pressure trait male 84.0 days 12 175.0 mmHg 3.0 10.39 tail cuff plethysmography 0.0 67226 730
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium content diet (4 %) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 164.0 mmHg 5.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67229 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -39.0 mmHg 1.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67235 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) (for 21 days) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -28.0 mmHg 3.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67243 731
SS.LEW-(D5Mco39-D5Mco57)(D5Mco41-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 205.0 mmHg 5.1 tail cuff plethysmography 0.0 restrained, 28 degrees C 70585 1482
SS.LEW-(D5Mco42-D5Mco47)/1Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 231.0 mmHg 4.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70592 1482
SHRSR/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 18 111.0 mmHg 0.94 4.0 tail cuff plethysmography 0.0 69125 1126
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 18 188.0 mmHg 2.83 12.0 tail cuff plethysmography 0.0 69131 1126
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 16 serial mean 125.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements 68741 990
WKY.SHRSP-(D1Rat171-D1Wox33)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 10 serial mean 124.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements for 68745 990
FHH/Eur systolic blood pressure unilateral nephrectomy Shiozawa M, et al., J Am Soc Nephrol 2000 Nov;11(11):2068-78. arterial blood pressure trait male 91.0 days-98.0 days 26 151.0 mmHg 1.96 10.0 tail cuff plethysmography 0.0 unilateral nephrectomy 39 days performed at 5 to 6 weeks of age 69142 1128
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 31 108.0 mmHg 0.9 5.0 tail cuff plethysmography 0.0 69172 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 26 197.0 mmHg 4.12 21.0 tail cuff plethysmography 0.0 69171 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 31 191.0 mmHg 0.72 4.0 tail cuff plethysmography 0.0 69182 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 33 186.0 mmHg 1.2 6.9 tail cuff plethysmography 0.0 69188 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 35 153.0 mmHg 2.03 12.0 tail cuff plethysmography 0.0 69196 1126
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 205.0 mmHg 3.4 tail cuff plethysmography 0.0 restrained, 28 degrees C 70580 1482
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 226.0 mmHg 4.0 21.91 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96984 1778
SHR-Ndufc2em1Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 10 undefined 183.0 mmHg 0.63 2.0 tail cuff plethysmography 0.0 97917 1938
SHR-Ndufc2em2Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 16 undefined 186.0 mmHg 1.5 6.0 tail cuff plethysmography 0.0 97927 1938
LH/Mav systolic blood pressure control condition Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. arterial blood pressure trait male 112.0 days 8 undefined 169.0 mmHg 5.0 14.14 tail cuff plethysmography 0.0 102808 2723
LH/Mav systolic blood pressure nifedipine (50 mg/kg/d) (for 42 days) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. arterial blood pressure trait male 63.0 days 7 undefined 144.0 mmHg 4.0 10.58 tail cuff plethysmography 0.0 102851 2761
SS heart rate controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart pumping trait male 84.0 days 7 443.0 beats/min 20.41 54.0 tail cuff plethysmography 0.0 103280 2803
SS systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 84.0 days 7 206.0 mmHg 2.27 6.0 tail cuff plethysmography 0.0 103286 2803
SS heart rate controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart pumping trait male 126.0 days 6 437.0 beats/min 20.0 49.0 tail cuff plethysmography 0.0 103282 2803
WKY systolic blood pressure controlled in utero environment (30 % of calories) (for 22 days) Riviere G, et al., Hypertension. 2005 Nov;46(5):1169-74. Epub 2005 Oct 3. arterial blood pressure trait male 112.0 days 6 undefined 125.0 mmHg 2.0 4.9 tail cuff plethysmography 0.0 101684 2218
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77.0 days 19 mean of 3 samples of undefined duration serial mean 128.0 mmHg 1.38 6.0 tail cuff plethysmography 0.0 102465 2689
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77.0 days 10 518.0 beats/min 3.48 11.0 tail cuff plethysmography 0.0 102498 2690
SR/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77.0 days 10 383.0 beats/min 6.96 22.0 tail cuff plethysmography 0.0 102504 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126.0 days 10 326.0 beats/min 13.28 42.0 tail cuff plethysmography 0.0 102507 2690
MWF systolic blood pressure control condition (for 280 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. arterial blood pressure trait male 280.0 days 10 undefined 171.0 mmHg 1.26 4.0 tail cuff plethysmography 0.0 100230 2459
WKY systolic blood pressure control condition (for 280 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. arterial blood pressure trait male 280.0 days 9 undefined 130.0 mmHg 2.33 7.0 tail cuff plethysmography 0.0 100232 2459
MWF systolic blood pressure control condition (for 420 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. arterial blood pressure trait male 402.0 days-420.0 days 10 undefined 181.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 Ages originally entered as low bound 420 days and high bound 402 days. 100235 2459
MWF systolic blood pressure lisinopril (80-100 mg/l) (for 70 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. arterial blood pressure trait male 350.0 days 10 undefined 138.0 mmHg 1.58 5.0 tail cuff plethysmography 0.0 100234 2459
SD-Tg(Ren2)27 systolic blood pressure control condition (for 0 hours) Cerutti C, et al., Physiol Genomics. 2006 Nov 27;27(3):295-308. doi: 10.1152/physiolgenomics.00318.2005. Epub 2006 Aug 1. arterial blood pressure trait male 84.0 days 6 203.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 103469 2826
LH/Mav systolic blood pressure control condition (for 0 hours) Cerutti C, et al., Physiol Genomics. 2006 Nov 27;27(3):295-308. doi: 10.1152/physiolgenomics.00318.2005. Epub 2006 Aug 1. arterial blood pressure trait male 84.0 days 5 161.0 mmHg 6.0 13.42 tail cuff plethysmography 0.0 103473 2826
WF/Mol heart rate vehicle control condition then artificial aortocaval fistula (for 9 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 7 460.0 beats/min 15.0 39.69 tail cuff plethysmography 0.0 acf 9 days 101375 2585
WF/Mol systolic blood pressure controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 106.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 sham acf 4 days 101345 2585
WF/Mol heart rate vehicle control condition then artificial aortocaval fistula (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 470.0 beats/min 12.0 26.83 tail cuff plethysmography 0.0 acf 2 days 101378 2585
MW systolic blood pressure right nephrectomy (for 84 days) then lisinopril (10 mg/kg/d) (for 28 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 129.4 mmHg 7.9 24.98 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 84 days 100873 2523
MW systolic blood pressure right nephrectomy (for 112 days) then angiotensin II receptor antagonist (80 mg/l) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 5 undefined 144.0 mmHg 9.1 20.35 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 112 days 100881 2523
SS mean arterial blood pressure controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 91.0 days 8 160.0 mmHg 4.6 13.0 tail cuff plethysmography 0.0 102268 2683
MW systolic blood pressure unilateral nephrectomy (for 14 days) and captopril (500 mg/l) (for 42 days) then puromycin aminonucleoside (100 mg/kg) then puromycin aminonucleoside (40 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 5 undefined 95.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 unx 42 days 101164 2581
MW systolic blood pressure control condition Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 18 undefined 119.0 mmHg 5.0 21.21 tail cuff plethysmography 0.0 control 29 days 101171 2581
SD systolic blood pressure unilateral nephrectomy (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 11 undefined 185.0 mmHg 7.84 26.0 tail cuff plethysmography 0.0 unx 13 days - 101548 2602
SD systolic blood pressure unilateral nephrectomy (for 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 8 undefined 201.0 mmHg 6.72 19.0 tail cuff plethysmography 0.0 unx 14 days 101615 2602
WF/Mol systolic blood pressure controlled ramipril content drinking water (3 mg/kg/d) (for 10 days) then artificial aortocaval fistula (for 9 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 7 undefined 110.0 mmHg 6.0 15.87 tail cuff plethysmography 0.0 acf 9 days 101352 2585
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 151.0 mmHg 5.0 11.18 tail cuff plethysmography 0.0 sham acf 2 days 101355 2585
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 160.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 sham acf 4 days 101361 2585
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 130.0 mmHg 3.0 7.35 tail cuff plethysmography 0.0 sham acf 7 days 101363 2585
WF/Mol heart rate vehicle control condition then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 7 450.0 beats/min 13.0 34.39 tail cuff plethysmography 0.0 acf 7 days 101372 2585
LL/Mav systolic blood pressure streptozotocin (100 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 56.0 days 18 mean of 3 samples of undefined duration serial mean 124.0 mmHg 3.0 12.73 tail cuff plethysmography 0.0 102703 2721
SS-Nppbem2Mcwi-/- diastolic blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84.0 days 6 serial mean 94.0 mmHg 11.0 26.94 tail cuff plethysmography 0.0 99823 2319
SS-Nppbem2Mcwi-/- diastolic blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84.0 days 7 serial mean 128.0 mmHg 22.0 58.21 tail cuff plethysmography 0.0 99822 2319
SS-Nppbem2Mcwi-/- diastolic blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 252.0 days 7 serial mean 145.0 mmHg 31.0 82.02 tail cuff plethysmography 0.0 99826 2319
SS-Nppbem2Mcwi-/- systolic blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168.0 days 6 serial mean 175.0 mmHg 8.0 19.6 tail cuff plethysmography 0.0 99831 2319
SS-Nppbem2Mcwi-/- mean arterial blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168.0 days 7 serial mean 158.0 mmHg 27.0 71.44 tail cuff plethysmography 0.0 99836 2319
SS-Nppbem2Mcwi-/- mean arterial blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168.0 days 6 serial mean 137.0 mmHg 11.0 26.94 tail cuff plethysmography 0.0 99837 2319
SD mean arterial blood pressure left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 9 113.0 mmHg 5.0 15.0 tail cuff plethysmography 0.0 unx 98939 2179
SD mean arterial blood pressure left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 9 148.0 mmHg 4.0 12.0 tail cuff plethysmography 0.0 unx 28 days 98942 2179
SD systolic blood pressure streptozotocin (60 mg/kg) then insulin Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. arterial blood pressure trait male  days 8 undefined 152.0 mmHg 1.06 3.0 tail cuff plethysmography 0.0 stz 154 days 99899 2358
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 382.0 beats/min 8.0 17.89 tail cuff plethysmography 0.0 sham acf 7 days 101388 2585
SD systolic blood pressure nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 6 serial mean 142.8 mmHg 6.4 15.68 tail cuff plethysmography 0.0 unx 84 days 100114 2419
SDT/Jcl systolic blood pressure nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 7 serial mean 128.6 mmHg 3.7 9.79 tail cuff plethysmography 0.0 unx 84 days 100115 2419
SD blood hemoglobin A1c level nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. blood hemoglobin amount male 140.0 days 8 3.2 % 0.1 0.28 tail cuff plethysmography 0.0 unx 84 days 100130 2419
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77.0 days 8 399.0 beats/min 8.84 25.0 tail cuff plethysmography 0.0 102416 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 63.0 days 8 mean of 3 samples of undefined duration serial mean 126.0 mmHg 2.12 6.0 tail cuff plethysmography 0.0 102430 2689
MWF/ZtmRrrc mean arterial blood pressure control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 126.0 days 8 undefined 129.0 mmHg 3.18 9.0 tail cuff plethysmography 0.0 100915 2541
SS.ZUC-Leprfa+/+/Slc systolic blood pressure bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. arterial blood pressure trait female 91.0 days 9 undefined 138.0 mmHg 1.0 3.0 tail cuff plethysmography 0.0 ovariectomy 42 days 101669 2622
SS.ZUC-Leprfa+/+/Slc heart rate bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91.0 days 12 392.0 beats/min 5.0 17.32 tail cuff plethysmography 0.0 ovariectomy 42 days 101674 2622
SS.ZUC-Leprfa-/-/Slc heart rate bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91.0 days 7 366.0 beats/min 8.0 21.17 tail cuff plethysmography 0.0 ovariectomy 42 days 101676 2622
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 130.0 days 6 mean of 3 samples - 1 per minute serial mean 148.0 mmHg 1.63 4.0 tail cuff plethysmography 0.0 100179 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure controlled enalapril content drinking water (5 mg/kg/d) (for 10 days) Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 130.0 days 4 mean of 3 samples - 1 per minute serial mean 129.0 mmHg 2.5 5.0 tail cuff plethysmography 0.0 100181 2439
SD systolic blood pressure controlled enalapril content drinking water (5 mg/kg/d) (for 10 days) Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 130.0 days 1 mean of 3 samples - 1 per minute serial mean 117.0 mmHg 4.0 4.0 tail cuff plethysmography 0.0 100178 2439
SD systolic blood pressure control condition Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. arterial blood pressure trait male  days 8 undefined 126.0 mmHg 1.06 3.0 tail cuff plethysmography 0.0 99925 2358
SD systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 180.0 days 3 mean of 3 samples - 1 per minute serial mean 134.0 mmHg 2.31 4.0 tail cuff plethysmography 0.0 100174 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 180.0 days 3 mean of 3 samples - 1 per minute serial mean 157.0 mmHg 1.73 3.0 tail cuff plethysmography 0.0 100173 2439
OLETF diastolic blood pressure olmesartan medoxomil (3.8 mg/kg/d) (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 12 undefined 100.8 mmHg 2.1 7.27 tail cuff plethysmography 0.0 99428 2298
MW systolic blood pressure right nephrectomy (for 56 days) then angiotensin II receptor antagonist (20 mg/l) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 7 undefined 204.3 mmHg 9.7 25.66 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 56 days 100867 2523
WI systolic blood pressure swimming (for 0.2 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. arterial blood pressure trait female  days 16 30 min mean continuous mean 125.2 mmHg 0.9 3.6 tail cuff plethysmography 1800.0 following 8 wk protocol 98740 2159
Crl:WI systolic blood pressure control condition (for 547 days) Ruiz-Torres MP, et al., J Am Soc Nephrol. 1998 May;9(5):782-91. arterial blood pressure trait male 547.0 days 10 146.0 mmHg 7.0 22.14 tail cuff plethysmography 0.0 101283 2584
SS.ZUC-Leprfa-/-/Slc systolic blood pressure control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. arterial blood pressure trait male 126.0 days 7 210.62 mmHg 2.54 6.72 tail cuff plethysmography 0.0 101890 2642
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 108.0 days-112.0 days 5 2.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 3months and 4 months 106732 3039
SBN/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 42.0 days 12 125.0 mmHg 2.0 6.93 tail cuff plethysmography 0.0 106748 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (between 24 and 28 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 192.0 days-196.0 days 5 54.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 n=5-7, change between age 6 months and 7 months 106738 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 276.0 days-280.0 days 5 51.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 n=5-7, change between age 9months and 10 months 106743 3039
SBH/Ygl systolic blood pressure control condition Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 28.0 days 5 140.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 106726 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (for 30 days) and deoxycorticosterone acetate (25 mg) (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 52.0 days-56.0 days 5 56.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 n=5-7, change between age 1month and 2 months 106731 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (between 24 and 28 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 360.0 days-364.0 days 5 53.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 12months and 13 months 106747 3039
SBN/Ygl systolic blood pressure control condition Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 28.0 days 5 128.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 106724 3039
SBN/Ygl systolic blood pressure control condition Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 28.0 days 5 126.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 106725 3039
MWF/FubRkb heart rate vehicle control condition (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. heart pumping trait male 112.0 days 10 352.3 beats/min 7.3 23.08 tail cuff plethysmography heart 0.0 109413 3140
Crl:WI heart rate finerenone (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. heart pumping trait male 112.0 days 10 351.9 beats/min 8.9 28.14 tail cuff plethysmography heart 0.0 109412 3140
MWF/FubRkb pulse wave velocity finerenone (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 5.6 /ms 0.5 1.58 tail cuff plethysmography 0.0 109418 3140
SHRSP/A3NCrl systolic blood pressure controlled sodium chloride content drinking water (1 %) (for 91 days) and controlled fat content diet (24.5 %) (for 91 days) then controlled SB-239063 content diet (1200 ppm) (for 35 days) Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. arterial blood pressure trait male 161.0 days-175.0 days 8 143.0 mmHg 6.0 16.97 tail cuff plethysmography 0.0 107384 3083
SHRSP/A3N systolic blood pressure reproduction condition Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. arterial blood pressure trait female 120.0 days-140.0 days 15 94.0 mmHg 10.0 38.73 tail cuff plethysmography 0.0 107571 3093
WAG systolic blood pressure diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 128.99 mmHg 5.59 14.78 tail cuff plethysmography 90 min 0.1% methylcellulose per os 108289 3101
WAG systolic blood pressure diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 129.07 mmHg 3.75 9.91 tail cuff plethysmography 150 min 0.1% methylcellulose per os 108293 3101
WAG systolic blood pressure proestrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 133.83 mmHg 1.96 5.19 tail cuff plethysmography 108297 3101
SHR systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 162.33 mmHg 0.62 1.63 tail cuff plethysmography 108304 3101
SHR systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 161.67 mmHg 3.51 9.29 tail cuff plethysmography 108306 3101
WAG systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 126.5 mmHg 1.7 4.51 tail cuff plethysmography 108307 3101
SHR systolic blood pressure estrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 161.57 mmHg 1.0 2.64 tail cuff plethysmography 108314 3101
SHR systolic blood pressure metestrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 172.71 mmHg 4.73 12.51 tail cuff plethysmography 108320 3101
SHR systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 163.71 mmHg 5.52 14.6 tail cuff plethysmography 108324 3101
SHR systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 159.14 mmHg 2.35 6.23 tail cuff plethysmography 108326 3101
SHR systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 165.86 mmHg 3.28 8.67 tail cuff plethysmography 108330 3101
WAG systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 128.14 mmHg 1.03 2.73 tail cuff plethysmography 108331 3101
SHR systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 163.71 mmHg 6.11 16.16 tail cuff plethysmography 108334 3101
SHR systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 163.96 mmHg 5.64 14.92 tail cuff plethysmography 108360 3101
WKY systolic blood pressure diclofenac (10 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 123.7 mmHg 1.06 2.8 tail cuff plethysmography 60 min IP 108359 3101
SHR systolic blood pressure diclofenac (20 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 160.57 mmHg 5.22 13.81 tail cuff plethysmography 60 min 0.1% methylcellulose per os 108362 3101
SHR systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 163.57 mmHg 8.15 21.55 tail cuff plethysmography 108364 3101
WKY systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 123.4 mmHg 0.76 2.0 tail cuff plethysmography 108365 3101
WAG/Nov systolic blood pressure physical restraint in tube type rodent restrainer (for 0.5 hours) Markel AL, et al., J Endocrinol. 2007 Dec;195(3):439-50. doi: 10.1677/JOE-07-0254. arterial blood pressure trait male 120.0 days-150.0 days 27 137.0 mmHg 3.0 15.59 tail cuff plethysmography 0.0 restraint 30 min 108638 3127
MWF systolic blood pressure control condition Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. arterial blood pressure trait male 126.0 days-140.0 days 6 146.0 mmHg 1.63 4.0 tail cuff plethysmography 0.0 110007 3163
MWF systolic blood pressure cyclosporine A (50 mg/kg/d) (for 6 days) and lacidipine (1 mg/kg/d) (for 6 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. arterial blood pressure trait male 132.0 days-146.0 days 7 143.0 mmHg 6.2 16.4 tail cuff plethysmography 0.0 110011 3163
WKY/NCrl heart rate standard condition (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. heart pumping trait male 203.0 days-224.0 days 10 307.0 beats/min 24.0 75.89 tail cuff plethysmography 0.0 standard rat chow 107120 3075
HanTac:WH mean arterial blood pressure control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. arterial blood pressure trait male 112.0 days 116.0 mmHg 1.0 tail cuff plethysmography 0.0 108030 3109
MWF/Ztm systolic blood pressure cilazapril (15 mg/kg/d) Iordache BE, etal., J Am Soc Nephrol. 1994 Dec;5(6):1378-84. arterial blood pressure trait male 252.0 days-253.0 days 5 130.0 mmHg 2.24 5.0 tail cuff plethysmography tail 0.0 109142 3136
MWF/Ztm systolic blood pressure cilazapril (15 mg/kg/d) Iordache BE, etal., J Am Soc Nephrol. 1994 Dec;5(6):1378-84. arterial blood pressure trait male 131.0 days 6 136.0 mmHg 2.45 6.0 tail cuff plethysmography tail 0.0 109145 3136
MWF/Ztm systolic blood pressure controlled lisinopril content drinking water (80 mg/l) (for 1 days) Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 280.0 days 8 186.0 mmHg 4.95 14.0 tail cuff plethysmography 0.0 109525 3147
MWF/Ztm systolic blood pressure controlled lisinopril content drinking water (80 mg/l) (for 70 days) Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 350.0 days 8 126.0 mmHg 3.18 9.0 tail cuff plethysmography 0.0 109526 3147
MWF/Ztm systolic blood pressure controlled lisinopril content drinking water (80 mg/l) (for 140 days) Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 420.0 days 8 126.0 mmHg 2.83 8.0 tail cuff plethysmography 0.0 109527 3147
WKY systolic blood pressure control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 350.0 days 4 124.0 mmHg 3.5 7.0 tail cuff plethysmography 0.0 109529 3147
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 202.0 mmHg 4.1 18.34 tail cuff plethysmography 0 average of 4days 65483 611
SS.LEW-(D1Rat211-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 180.0 mmHg 2.8 12.52 tail cuff plethysmography 0 average of 4days 65488 611
SHR.WKY-(D1Got158-D1Got161)/Njs systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 112.0 days-114.0 days 17 166.1 mmHg 0.61 2.5 tail cuff plethysmography 65252 564
SHR/NCruk systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 112.0 days-114.0 days 20 174.0 mmHg 0.31 1.4 tail cuff plethysmography 65250 564
SHR.WKY-(D1Rat420-D1Rat278)/Njs systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 140.0 days-142.0 days 13 191.8 mmHg 0.28 1.0 tail cuff plethysmography 65257 564
SS.LEW-(D1Mco102-D1Got46)/Mco systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 188.0 mmHg 3.5 15.65 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65308 565
SS/JrSeac systolic blood pressure controlled sodium content diet (8 %) (for 35 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 77.0 days 5 246.0 mmHg 10.73 24.0 tail cuff plethysmography 0.0 67249 733
SS/JrSeac systolic blood pressure controlled sodium content diet (0.3 %) (for 84 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 126.0 days 5 117.0 mmHg 11.18 25.0 tail cuff plethysmography 0.0 67250 733
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (for 21 days) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -39.0 mmHg 3.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67261 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) (for 21 days) then ruthenium red (3 mg/kg) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -22.0 mmHg 1.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67267 731
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 20 222.0 mmHg 5.01 22.41 tail cuff plethysmography 0.0 67311 749
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 206.6 mmHg 2.4 10.73 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65793 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 210.6 mmHg 3.4 15.21 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65792 237
LEW/NIcoCrlf systolic blood pressure physical restraint in tube type rodent restrainer Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 arterial blood pressure trait male 70.0 days-77.0 days 5 161.0 mmHg 4.0 8.94 tail cuff plethysmography 0 11616 108
SS.SHR-(D9Mco72-D9Mco106)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 176.0 mmHg 5.24 tail cuff plethysmography 0.0 67520 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 213.0 mmHg 5.14 tail cuff plethysmography 0.0 67524 749
SS.SHR-(D9Rat7-D9Rat84)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 185.0 mmHg 4.84 tail cuff plethysmography 0.0 67522 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 200.0 mmHg 4.22 tail cuff plethysmography 0.0 67521 749
SHR/NHsd systolic blood pressure controlled sodium content diet (4 %) (for 28 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 81.0 days 10 204.0 mmHg 3.9 12.33 tail cuff plethysmography 0 66120 691
SHRSP/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait male 91.0 days 5 219.6 mmHg 6.8 15.21 tail cuff plethysmography 11678 115
SS.SR-(D3Mco19-D3Mco5)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6. arterial blood pressure trait male 61.0 days-65.0 days 19 serial mean 181.3 mmHg 2.2 9.59 tail cuff plethysmography average of 12 readings from 4 sessions 11776 145
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6. arterial blood pressure trait male 61.0 days-65.0 days 20 serial mean 202.7 mmHg 3.7 16.55 tail cuff plethysmography average of 12 readings from 4 sessions 11775 145
SS.MNS-(D10Mco14-D10Mit11)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 175.0 mmHg 1.7 7.6 tail cuff plethysmography average of 12 readings from 4 daily sessions 11832 148
SS.MNS-(D10Mco62-D10Mco30)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 180.0 mmHg 2.86 12.79 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12132 232
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 198.0 mmHg 3.96 17.71 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12131 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 10 serial mean 132.0 mmHg 3.1 9.8 tail cuff plethysmography tail 0 12165 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 10 serial mean 159.0 mmHg 2.0 6.32 tail cuff plethysmography tail 0 12168 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 8 serial mean 135.0 mmHg 5.1 14.42 tail cuff plethysmography tail 0 12173 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 8 serial mean 141.0 mmHg 3.3 9.33 tail cuff plethysmography tail 0 12172 222
SS.LEW-(D10Mco84-D10Mco134)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 187.0 mmHg 2.67 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11916 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 195.0 mmHg 3.27 14.62 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12807 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 203.0 mmHg 2.98 13.33 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12809 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 231.0 mmHg 3.3 14.76 tail cuff plethysmography average of 3-4 consistent readings 12450 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 221.0 mmHg 3.44 15.38 tail cuff plethysmography average of 3-4 consistent readings 12454 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 218.0 mmHg 3.83 17.13 tail cuff plethysmography average of 3-4 consistent readings 12455 266
SS.LEW-(D1Uia8-D1Rat124)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 195.0 mmHg 1.7 7.6 tail cuff plethysmography average of 3-4 consistent readings 12473 266
F344/Snk systolic blood pressure control condition Ohno Y, et al., Am J Hypertens. 2007 Feb;20(2):172-6. arterial blood pressure trait not specified 105.0 days 16 136.0 mmHg 1.25 5.0 tail cuff plethysmography 0.0 64881 301
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 40 serial mean 216.0 mmHg 2.4 15.18 tail cuff plethysmography tail 0 64736 222
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 65.0 days-68.0 days 20 data obtained at three consistent sessions per day serial mean 175.0 mmHg tail cuff plethysmography 345600 65968 650
BN/Crl systolic blood pressure control condition Viel EC, et al., Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H938-44. Epub 2009 Dec 31. arterial blood pressure trait male 84.0 days 12 113.0 mmHg 5.0 17.32 tail cuff plethysmography 0.0 67227 730
SS/HsdMcwiCrl mean arterial blood pressure control condition (0.15 %) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 107.0 mmHg 4.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67232 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -14.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67236 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -31.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67238 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -4.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67242 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -5.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67241 731
SS.LEW-(D5Mco39-D5Mco57)/3Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 184.0 mmHg 4.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70590 1482
SS.LEW-(D5Mco39-D5Mco57)/1Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 199.0 mmHg 4.2 tail cuff plethysmography 0.0 restrained, 28 degrees C 70588 1482
MWF/FubRkb systolic blood pressure control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. arterial blood pressure trait female 168.0 days 18 138.5 mmHg 1.2 5.09 tail cuff plethysmography 0.0 68174 309
SHR/FubRkb systolic blood pressure control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. arterial blood pressure trait female 168.0 days 10 157.1 mmHg 2.9 9.17 tail cuff plethysmography 0.0 68172 309
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 18 199.0 mmHg 0.24 1.0 tail cuff plethysmography 0.0 69130 1126
ISIAH systolic blood pressure control condition Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. arterial blood pressure trait not specified 180.0 days 11 175.0 mmHg 4.8 15.92 tail cuff plethysmography 0.0 68063 835
WKY.SHRSP-(Ntrk3-D1Smu13)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 18 serial mean 122.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements 68743 990
ACI/Eur systolic blood pressure unilateral nephrectomy Shiozawa M, et al., J Am Soc Nephrol 2000 Nov;11(11):2068-78. arterial blood pressure trait male 91.0 days-98.0 days 21 113.0 mmHg 1.96 9.0 tail cuff plethysmography 0.0 unilateral nephrectomy 39 days performed at 5 to 6 weeks of age 69141 1128
SS/NEisSlc systolic blood pressure controlled sodium content diet (8 %) (for 28 days) then controlled sodium content diet (0.3 %) (for 28 days) Kitada K, et al., PLoS One. 2012;7(7):e41896. Epub 2012 Jul 24. arterial blood pressure trait male 98.0 days 10 144.0 mmHg 4.0 12.65 tail cuff plethysmography 0.0 69687 736
SHRSP/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 26 187.0 mmHg 2.55 13.0 tail cuff plethysmography 0.0 69163 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 33 174.0 mmHg 3.31 19.0 tail cuff plethysmography 0.0 69167 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 146.0 mmHg 1.26 7.0 tail cuff plethysmography 0.0 69173 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 34 192.0 mmHg 0.79 4.6 tail cuff plethysmography 0.0 69198 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 5 198.0 mmHg 1.34 3.0 tail cuff plethysmography 0.0 69200 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 1 193.0 mmHg tail cuff plethysmography 0.0 69201 1126
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 191.0 mmHg 2.1 tail cuff plethysmography 0.0 restrained, 28 degrees C 70582 1482
Crl:SD systolic blood pressure controlled fructose content diet (66 %) (between 14 and 28 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. arterial blood pressure trait male 63.0 days-77.0 days 9 159.0 mmHg 2.0 6.0 tail cuff plethysmography tail 0.0 F 75851 1540
SHRSP/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 18 serial mean 213.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements for 84602 990
SS.LEW-(D1Mco36-D1Mco54)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 226.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96940 1778
SS.LEW-(D1Rat200-D1Mco136)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 212.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96943 1778
SS.LEW-(D1Mco36-D1Mco101)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 173.0 mmHg 1.0 5.48 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96985 1778
SS.LEW-(D1Mco36-D1Mco61)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 227.0 mmHg 7.0 38.34 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96942 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 194.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96981 1778
SHRSP/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 18 undefined 181.0 mmHg 3.3 14.0 tail cuff plethysmography 0.0 97914 1938
SHR-Ndufc2em2Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 12 undefined 181.0 mmHg 0.87 3.0 tail cuff plethysmography 0.0 97922 1938
LH/Mav systolic blood pressure control condition Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. arterial blood pressure trait male 112.0 days 4 undefined 157.0 mmHg 7.0 14.0 tail cuff plethysmography 0.0 102809 2723
SR systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 42.0 days 5 104.0 mmHg 2.68 6.0 tail cuff plethysmography 0.0 103285 2803
SS systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 126.0 days 6 197.0 mmHg 6.94 17.0 tail cuff plethysmography 0.0 103288 2803
WKY systolic blood pressure controlled in utero environment (100 % of calories) (for 22 days) Riviere G, et al., Hypertension. 2005 Nov;46(5):1169-74. Epub 2005 Oct 3. arterial blood pressure trait male 112.0 days 5 undefined 104.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 101683 2218
WKY mean arterial blood pressure controlled in utero environment (100 % of calories) (for 22 days) Riviere G, et al., Hypertension. 2005 Nov;46(5):1169-74. Epub 2005 Oct 3. arterial blood pressure trait male 112.0 days 5 undefined 66.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 101685 2218
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77.0 days 19 347.0 beats/min 7.34 32.0 tail cuff plethysmography 0.0 102456 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (9.6 ug/d) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77.0 days 14 mean of 3 samples of undefined duration serial mean 150.0 mmHg 2.67 10.0 tail cuff plethysmography 0.0 102467 2689
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 126.0 days 10 481.0 beats/min 13.91 44.0 tail cuff plethysmography 0.0 102499 2690
LH/Mav systolic blood pressure streptozotocin (75 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 112.0 days 14 mean of 3 samples of undefined duration serial mean 179.0 mmHg 4.0 14.97 tail cuff plethysmography 0.0 102729 2721
MWF systolic blood pressure control condition (for 350 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. arterial blood pressure trait male 350.0 days 10 undefined 173.0 mmHg 1.58 5.0 tail cuff plethysmography 0.0 100233 2459
MWF systolic blood pressure lisinopril (80-100 mg/l) (for 140 days) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. arterial blood pressure trait male 420.0 days 10 undefined 130.0 mmHg 8.22 26.0 tail cuff plethysmography 0.0 100236 2459
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then artificial aortocaval fistula (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 482.0 beats/min 12.0 29.39 tail cuff plethysmography 0.0 acf 2 days 101376 2585
SR/Hsd mean arterial blood pressure standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 49.0 days 8 120.0 mmHg 1.06 3.0 tail cuff plethysmography 0.0 102267 2683
SS mean arterial blood pressure standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. arterial blood pressure trait male 49.0 days 8 124.0 mmHg 2.12 6.0 tail cuff plethysmography 0.0 102266 2683
MW systolic blood pressure unilateral nephrectomy (for 14 days) and captopril (500 mg/l) (for 14 days) then puromycin aminonucleoside (100 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 5 undefined 94.0 mmHg 3.0 6.71 tail cuff plethysmography 0.0 unx 14 days 101160 2581
MW systolic blood pressure control condition Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 18 undefined 120.0 mmHg 4.0 16.97 tail cuff plethysmography 0.0 control 17 days 101166 2581
MW systolic blood pressure doxorubicin (2 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 7 undefined 137.0 mmHg 4.0 10.58 tail cuff plethysmography 0.0 doxorubicin 29 days 101170 2581
SD systolic blood pressure sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 6 undefined 118.0 mmHg 3.67 9.0 tail cuff plethysmography 0.0 sham unx 13 days 101547 2602
SD systolic blood pressure unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 5 undefined 149.0 mmHg 9.39 21.0 tail cuff plethysmography 0.0 unx 13 days 101550 2602
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then artificial aortocaval fistula (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 98.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 acf 2 days 101354 2585
WF/Mol systolic blood pressure vehicle control condition then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 123.0 mmHg 3.0 7.35 tail cuff plethysmography 0.0 acf 7 days 101364 2585
WF/Mol heart rate controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 402.0 beats/min 31.0 69.32 tail cuff plethysmography 0.0 sham acf 7 days 101371 2585
SS-Nppbem2Mcwi-/- diastolic blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168.0 days 6 serial mean 118.0 mmHg 13.0 31.84 tail cuff plethysmography 0.0 99825 2319
SS-Nppbem2Mcwi-/- systolic blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84.0 days 7 serial mean 172.0 mmHg 13.0 34.39 tail cuff plethysmography 0.0 99828 2319
SS-Nppbem2Mcwi-/- systolic blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 168.0 days 7 serial mean 195.0 mmHg 30.0 79.37 tail cuff plethysmography 0.0 99830 2319
SS-Nppbem2Mcwi-/- mean arterial blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84.0 days 7 serial mean 142.0 mmHg 12.0 31.75 tail cuff plethysmography 0.0 99834 2319
SS-Nppbem2Mcwi-/- mean arterial blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84.0 days 6 serial mean 109.0 mmHg 11.0 26.94 tail cuff plethysmography 0.0 99835 2319
LH/Mav systolic blood pressure vehicle control condition Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. arterial blood pressure trait male 49.0 days-56.0 days 8 undefined 136.0 mmHg 3.0 8.49 tail cuff plethysmography 0.0 102645 2703
SD mean arterial blood pressure left nephrectomy then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 111.0 mmHg 4.0 10.58 tail cuff plethysmography 0.0 unx 98940 2179
SD mean arterial blood pressure left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 143.0 mmHg 7.0 18.52 tail cuff plethysmography 0.0 unx 28 days 98941 2179
SD mean arterial blood pressure left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 161.0 mmHg 7.0 18.52 tail cuff plethysmography 0.0 unx 56 days 98944 2179
SD mean arterial blood pressure left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 155.0 mmHg 3.0 7.94 tail cuff plethysmography 0.0 unx 56 days 98946 2179
SD mean arterial blood pressure left nephrectomy (for 56 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 9 153.0 mmHg 8.0 24.0 tail cuff plethysmography 0.0 unx 56 days 98945 2179
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 366.0 beats/min 12.0 26.83 tail cuff plethysmography 0.0 sham acf 4 days 101383 2585
WF/Mol heart rate controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 407.0 beats/min 16.0 39.19 tail cuff plethysmography 0.0 sham acf 7 days 101385 2585
SDT/Jcl systolic blood pressure nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 6 serial mean 131.8 mmHg 5.8 14.21 tail cuff plethysmography 0.0 unx 84 days 100113 2419
SS/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 70.0 days 7 373.0 beats/min 3.78 10.0 tail cuff plethysmography 0.0 102414 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 70.0 days 8 mean of 3 samples of undefined duration serial mean 124.0 mmHg 3.18 9.0 tail cuff plethysmography 0.0 102431 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 70.0 days 7 mean of 3 samples of undefined duration serial mean 166.0 mmHg 1.89 5.0 tail cuff plethysmography 0.0 102432 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77.0 days 8 mean of 3 samples of undefined duration serial mean 169.0 mmHg 2.47 7.0 tail cuff plethysmography 0.0 102434 2689
SDT/Jcl systolic blood pressure controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 6 serial mean 114.9 mmHg 3.1 7.59 tail cuff plethysmography 0.0 100111 2419
SD systolic blood pressure controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 6 serial mean 113.6 mmHg 4.1 10.04 tail cuff plethysmography 0.0 100112 2419
MWF/ZtmRrrc mean arterial blood pressure control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 246.0 days 8 undefined 146.0 mmHg 2.12 6.0 tail cuff plethysmography 0.0 100919 2541
MWF/ZtmRrrc mean arterial blood pressure enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 126.0 days 8 undefined 114.0 mmHg 4.95 14.0 tail cuff plethysmography 0.0 100918 2541
WKY systolic blood pressure controlled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 5 95.0 mmHg 9.0 20.12 tail cuff plethysmography 0.0 PA IV 50mg/kg 15 days 100447 2479
WKY systolic blood pressure 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 8 117.0 mmHg 2.0 5.66 tail cuff plethysmography 0.0 100448 2479
WKY systolic blood pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 8 113.0 mmHg 4.0 11.31 tail cuff plethysmography 0.0 PA IV 50mg/kg 490 days 100452 2479
WKY systolic blood pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 9 121.0 mmHg 2.0 6.0 tail cuff plethysmography 0.0 PA IV 50mg/kg 100449 2479
WKY systolic blood pressure controlled enalapril content drinking water (50 mg/l) (between 63 and 77 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 8 100.0 mmHg 1.0 2.83 tail cuff plethysmography 0.0 PA IV 50mg/kg 100450 2479
SD systolic blood pressure sham surgical control condition (for 140 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. arterial blood pressure trait male 189.0 days 6 undefined 144.0 mmHg 2.0 4.9 tail cuff plethysmography 0.0 sham lad occlusion 140 days 101090 2564
SS.ZUC-Leprfa-/-/Slc heart rate bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart pumping trait female 91.0 days 8 339.0 beats/min 11.0 31.11 tail cuff plethysmography 0.0 ovariectomy 42 days 101675 2622
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 120.0 days 6 mean of 3 samples - 1 per minute serial mean 146.0 mmHg 2.04 5.0 tail cuff plethysmography 0.0 100177 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure controlled losartan content drinking water (5 mg/kg/d) (for 10 days) Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 130.0 days 4 mean of 3 samples - 1 per minute serial mean 125.0 mmHg 1.5 3.0 tail cuff plethysmography 0.0 100183 2439
SD systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 120.0 days 1 mean of 3 samples - 1 per minute serial mean 121.0 mmHg tail cuff plethysmography 0.0 100188 2439
SD systolic blood pressure streptozotocin (60 mg/kg) then insulin Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. arterial blood pressure trait male  days 8 undefined 150.0 mmHg 1.41 4.0 tail cuff plethysmography 0.0 stz 224 days 99923 2358
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 60.0 days 15 mean of 3 samples - 1 per minute serial mean 126.0 mmHg 1.29 5.0 tail cuff plethysmography 0.0 100167 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 120.0 days 15 mean of 3 samples - 1 per minute serial mean 147.0 mmHg 1.29 5.0 tail cuff plethysmography 0.0 100171 2439
WI heart rate swimming with water weights (for 1 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. heart pumping trait female  days 16 continuous mean 298.6 beats/min 3.3 13.2 tail cuff plethysmography 1800.0 swim 1 days following 8 wk protocol 98745 2159
OLETF systolic blood pressure olmesartan medoxomil (0.35 mg/kg/d) (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 11 undefined 138.9 mmHg 5.0 16.58 tail cuff plethysmography 0.0 99422 2298
LETO diastolic blood pressure control condition (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 11 undefined 98.2 mmHg 3.4 11.28 tail cuff plethysmography 0.0 99430 2298
MW systolic blood pressure right nephrectomy (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 6 undefined 182.5 mmHg 6.6 16.17 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 56 days 100862 2523
MW systolic blood pressure right nephrectomy (for 56 days) then captopril (30 mg/kg/d) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 177.0 mmHg 5.0 15.81 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 56 days 100864 2523
MW systolic blood pressure right nephrectomy (for 56 days) then lisinopril (10 mg/kg/d) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 189.5 mmHg 7.0 22.14 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 56 days 100866 2523
WI diastolic blood pressure swimming (for 0.2 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. arterial blood pressure trait female  days 16 30 min mean continuous mean 98.1 mmHg 1.9 7.6 tail cuff plethysmography 1800.0 following 8 wk protocol 98742 2159
SS.ZUC-Leprfa-/-/Slc heart rate control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. heart pumping trait male 126.0 days 7 400.73 beats/min 15.4 40.74 tail cuff plethysmography 0.0 101892 2642
SS/JrHsdMcwi systolic blood pressure control condition (for 147 days) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. arterial blood pressure trait male 147.0 days 8 191.0 mmHg 5.0 14.14 tail cuff plethysmography 0.0 105861 3023
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (8 %) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98.0 days 7 181.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 106697 3038
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (8 %) (for 42 days) then streptozotocin (60 mg/kg) then insulin (10 ul) (for 42 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98.0 days 7 181.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 106699 3038
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (for 30 days) and deoxycorticosterone acetate (25 mg) (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 52.0 days-56.0 days 5 6.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 n=5-7, change between age 1month and 2 months 106729 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (for 30 days) and deoxycorticosterone acetate (25 mg) (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 52.0 days-56.0 days 5 52.0 mmHg 3.0 6.71 tail cuff plethysmography 0.0 n=5-7, change between age 1month and 2 months 106730 3039
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 276.0 days-280.0 days 5 0.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 9months and 10 months 106740 3039
MWF/Ztm systolic blood pressure standard diet Iordache BE, etal., J Am Soc Nephrol. 1994 Dec;5(6):1378-84. arterial blood pressure trait male 131.0 days 6 151.0 mmHg 2.86 7.0 tail cuff plethysmography tail 0.0 109143 3136
MWF/FubRkb systolic blood pressure finerenone (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 133.9 mmHg 9.0 28.46 tail cuff plethysmography 0.0 109410 3140
MWF/FubRkb pulse wave velocity vehicle control condition (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 5.6 /ms 0.5 1.58 tail cuff plethysmography 0.0 109417 3140
Crl:WI pulse wave velocity vehicle control condition (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 5.4 /ms 0.5 1.58 tail cuff plethysmography 0.0 109415 3140
Crl:WI pulse wave velocity finerenone (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 5.3 /ms 0.5 1.58 tail cuff plethysmography 0.0 109416 3140
SHRSP/A3NCrl systolic blood pressure controlled sodium chloride content drinking water (1 %) (for 91 days) and controlled fat content diet (24.5 %) (for 91 days) then vehicle control condition (for 35 days) Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. arterial blood pressure trait male 161.0 days-175.0 days 6 162.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 107385 3083
WKY/N systolic blood pressure control condition Furspan PB, etal., J Hypertens. 1987 Jun;5(3):293-7. doi: 10.1097/00004872-198706000-00005. arterial blood pressure trait both 180.0 days-270.0 days 9 109.0 mmHg 7.0 21.0 tail cuff plethysmography 0.0 107636 3094
MWF/ZtmRrrc mean arterial blood pressure enalapril (50 mg/l) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 70.0 days 6 undefined 151.0 mmHg 2.45 6.0 tail cuff plethysmography 0.0 107648 2541
MWF/ZtmRrrc mean arterial blood pressure enalapril (50 mg/l) (for 180 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 250.0 days 6 undefined 141.0 mmHg 2.86 7.0 tail cuff plethysmography 0.0 107649 2541
WAG systolic blood pressure diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 134.58 mmHg 3.76 9.96 tail cuff plethysmography 60 min 0.1% methylcellulose per os 108287 3101
SHR systolic blood pressure diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 143.46 mmHg 7.11 18.8 tail cuff plethysmography 120 min 0.1% methylcellulose per os 108290 3101
WAG systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 127.83 mmHg 0.88 2.32 tail cuff plethysmography 108299 3101
SHR systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 166.83 mmHg 1.0 2.64 tail cuff plethysmography 108298 3101
SHR systolic blood pressure estrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 169.29 mmHg 2.14 5.65 tail cuff plethysmography 108308 3101
WAG systolic blood pressure metestrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 132.29 mmHg 2.97 7.87 tail cuff plethysmography 108321 3101
WAG systolic blood pressure estrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 128.43 mmHg 4.49 11.89 tail cuff plethysmography 108319 3101
WAG systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 124.0 mmHg 1.89 5.0 tail cuff plethysmography 108323 3101
WAG systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 120.0 mmHg 3.08 8.16 tail cuff plethysmography 108325 3101
SHR systolic blood pressure diestrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 164.86 mmHg 2.59 6.84 tail cuff plethysmography 108332 3101
WAG systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 127.14 mmHg 2.14 5.67 tail cuff plethysmography 108335 3101
SHR systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 161.14 mmHg 4.01 10.62 tail cuff plethysmography 108340 3101
SHR systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 177.0 mmHg 0.91 2.4 tail cuff plethysmography 108356 3101
SHR systolic blood pressure diclofenac (10 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 165.9 mmHg 1.59 4.2 tail cuff plethysmography 60 min IP 108358 3101
WKY systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 122.8 mmHg 0.6 1.6 tail cuff plethysmography 108361 3101
Crl:SD systolic blood pressure controlled protein content diet (20 %) then perindopril (1 mg/kg/d) (for 120 days) Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6. arterial blood pressure trait male 540.0 days-660.0 days 8 130.0 mmHg 7.0 19.8 tail cuff plethysmography tail 0.0 108594 3126
MWF systolic blood pressure castor oil (for 6 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. arterial blood pressure trait male 132.0 days-146.0 days 7 157.0 mmHg 5.63 14.9 tail cuff plethysmography 0.0 110009 3163
WKY/NMolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 420.0 days 11 104.0 mmHg 1.8 5.97 tail cuff plethysmography 0.0 10 consecutive measurements 106934 3071
SHRSP/A3N systolic blood pressure controlled sodium chloride content drinking water (1 %) (for 84 days) and controlled fat content diet (24.5 %) (for 84 days) and vehicle control condition (for 84 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. arterial blood pressure trait male 168.0 days-189.0 days 6 serial mean 284.0 mmHg 8.0 19.6 tail cuff plethysmography tail 0.0 average 3 week intervals for 12 weeks 107499 3090
SHRSP/A3N systolic blood pressure controlled sodium chloride content drinking water (1 %) (for 84 days) and controlled fat content diet (24.5 %) (for 84 days) and eprosartan (60 mg/kg/d) (for 84 days) Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. arterial blood pressure trait male 168.0 days-189.0 days 6 serial mean 250.0 mmHg 9.0 22.05 tail cuff plethysmography tail 0.0 average 3 week intervals for 12 weeks 107500 3090
GK/MolTac mean arterial blood pressure control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. arterial blood pressure trait male 154.0 days 127.0 mmHg 4.0 tail cuff plethysmography 0.0 108033 3109
MWF/FubRkb systolic blood pressure control condition Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. arterial blood pressure trait male 84.0 days 10 146.0 mmHg 1.0 3.16 tail cuff plethysmography 0.0 109283 3141
MWF-Chr 6SHR/Rkb systolic blood pressure control condition Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. arterial blood pressure trait male 84.0 days 10 151.0 mmHg 1.6 5.06 tail cuff plethysmography 0.0 109287 3141
MHS/Gib systolic blood pressure controlled sodium chloride content diet (2.5 g/kg) Ferrandi M, etal., Am J Physiol. 1999 Oct;277(4):H1338-49. doi: 10.1152/ajpheart.1999.277.4.H1338. arterial blood pressure trait male 91.0 days 167.0 mmHg 2.0 tail cuff plethysmography 0.0 110652 3135
Hsd:WI systolic blood pressure control condition Rothermund L, etal., J Hypertens. 2006 Sep 24(9). arterial blood pressure trait male 100.0 days 16 138.0 mmHg 8.0 32.0 tail cuff plethysmography 0.0 108097 3115
SHRSP/A3N systolic blood pressure standard condition (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. arterial blood pressure trait male 203.0 days-224.0 days 10 253.0 mmHg 9.0 28.46 tail cuff plethysmography tail 0.0 standard rat chow 107097 3075
MWF/Fub systolic blood pressure controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. arterial blood pressure trait male 100.0 days-103.0 days 8 133.0 mmHg 3.0 8.49 tail cuff plethysmography tail 0.0 109023 3134
SS.LEW-(D1Mco75-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 182.0 mmHg 3.3 14.76 tail cuff plethysmography 0 average of 4days 65487 611
SHR.WKY-(D1Rat420-D1Rat278)/Njs systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 112.0 days-114.0 days 13 174.0 mmHg 0.64 2.3 tail cuff plethysmography 65253 564
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 36 and 40 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 66.0 days-70.0 days 20 serial mean 190.0 mmHg 5.4 24.15 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65309 565
SHR.WKY-(D1Wox19-D1Wox34)/Njs mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 140.0 days 31 continuous mean 195.3 mmHg 1.96 10.9 tail cuff plethysmography animals were prewarmed to 34 degrees C for 20 min before BP 65087 206
SS/Jr systolic blood pressure controlled sodium content diet Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 53.0 days 10 151.0 mmHg 5.1 16.13 tail cuff plethysmography 0 66115 691
SS.SR-(D3Mco36-D3Got159)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 178.6 mmHg 4.0 17.89 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65798 237
SS.SR-(D3Mco36-D3Got166)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 197.5 mmHg 2.5 15.81 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65797 237
SS.SR-(D3Mco36-D3Mco46)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 201.3 mmHg 2.2 13.91 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65796 237
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (for 21 days) then ruthenium red (3 mg/kg) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -31.0 mmHg 1.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67266 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) (for 21 days) then ruthenium red (3 mg/kg) then dihydrocapsaicin (30 ug/kg) and pentobarbital (50 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -21.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67265 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then apamin (100 ug/kg) and charybdotoxin (100 ug/kg) and 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -10.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67275 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then apamin (100 ug/kg) and charybdotoxin (100 ug/kg) and 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -7.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67276 731
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 203.6 mmHg 4.2 18.78 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65794 237
SS/Jr systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 84.0 days-85.0 days 6 serial mean 182.0 mmHg 4.1 10.04 tail cuff plethysmography tail 2 days between 7 am and 12 pm 11588 104
SS/Jr systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 140.0 days-141.0 days 6 serial mean 193.0 mmHg 10.5 25.72 tail cuff plethysmography tail 2 days between 7 am and 12 pm 11592 104
SHR/NHsd systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 84.0 days-85.0 days 6 serial mean 187.0 mmHg 5.2 12.74 tail cuff plethysmography tail 2 days between 7 am and 12 pm 11589 104
SHR/NHsd systolic blood pressure control condition Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87 arterial blood pressure trait male 182.0 days-183.0 days 6 serial mean 193.0 mmHg 9.5 23.27 tail cuff plethysmography tail 2 days between 7 am and 12 pm 11597 104
LEW/NIcoCrlf systolic blood pressure physical restraint in tube type rodent restrainer Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 arterial blood pressure trait female 70.0 days-77.0 days 6 157.0 mmHg 2.0 4.9 tail cuff plethysmography 0 11618 108
SHR/NIcoCrlf systolic blood pressure physical restraint in tube type rodent restrainer Ramos A, et al., Behav Brain Res. 1998 Nov;96(1-2):195-205 arterial blood pressure trait female 70.0 days-77.0 days 12 194.0 mmHg 2.0 6.93 tail cuff plethysmography 11619 108
WKY/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait female 91.0 days 5 127.0 mmHg 5.0 11.18 tail cuff plethysmography 0 11683 115
SS/Jr systolic blood pressure controlled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 100.0 days 21 serial mean 244.0 mmHg 6.2 28.41 tail cuff plethysmography 11781 146
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 20 serial mean 178.0 mmHg 4.3 19.23 tail cuff plethysmography 11788 146
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 22 serial mean 264.0 mmHg 5.5 25.8 tail cuff plethysmography 11791 146
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait female 61.0 days 12 serial mean 215.5 mmHg 8.5 29.44 tail cuff plethysmography 11794 146
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 230.6 mmHg 4.7 21.02 tail cuff plethysmography average of 12 readings from 4 daily sessions 11807 147
SS.SR-(D7Rat16-D7Rat176)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 19 serial mean 223.7 mmHg 4.0 17.44 tail cuff plethysmography average of 12 readings from 4 daily sessions 11826 147
SS.SR-(D7Mco7-D7Wox19)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 209.0 mmHg 2.2 9.84 tail cuff plethysmography average of 12 readings from 4 daily sessions 11820 147
SS.MNS-(D10Mco10-Aldoc)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 214.0 mmHg 3.6 16.1 tail cuff plethysmography average of 12 readings from 4 daily sessions 11838 148
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 217.0 mmHg 3.4 16.66 tail cuff plethysmography 11845 150
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 204.0 mmHg 2.84 12.7 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12127 232
SS.MNS-(D10Mco30-D10Got101)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 190.0 mmHg 2.4 10.73 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12137 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 10 serial mean 141.0 mmHg 3.2 10.12 tail cuff plethysmography tail 0 12166 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 10 serial mean 150.0 mmHg 3.5 11.07 tail cuff plethysmography tail 0 12167 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 10 serial mean 143.0 mmHg 1.9 6.01 tail cuff plethysmography tail 0 11910 222
SS.LEW-(D10Mco113-D10Got93)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 199.0 mmHg 2.04 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11915 205
SS.LEW-(D1Mco99-D1Rat49)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 197.0 mmHg 3.99 17.84 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12823 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 222.0 mmHg 3.7 16.55 tail cuff plethysmography average of 3-4 consistent readings 12453 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 209.0 mmHg 3.26 14.58 tail cuff plethysmography average of 3-4 consistent readings 12457 266
SS.LEW-(D1Mco2-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 192.0 mmHg 1.47 6.57 tail cuff plethysmography average of 3-4 consistent readings 12460 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 191.0 mmHg 3.48 15.56 tail cuff plethysmography average of 3-4 consistent readings 12459 266
SHR/Mol systolic blood pressure control condition Kloting I, et al., Biochem Biophys Res Commun 2001 Jun 29;284(5):1126-33. arterial blood pressure trait not specified 70.0 days-98.0 days 24 196.0 mmHg 2.04 10.0 tail cuff plethysmography tail 0.0 12924 323
SS.SHR-(D9Mco72-D9Mco105)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 20 183.0 mmHg 4.15 18.56 tail cuff plethysmography 0.0 67508 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 197.0 mmHg 3.85 tail cuff plethysmography 0.0 67513 749
SS.SHR-(D9Rat7-D9Got111)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 183.0 mmHg 4.14 tail cuff plethysmography 0.0 67523 749
SHR/Snk systolic blood pressure control condition Ohno Y, et al., Am J Hypertens. 2007 Feb;20(2):172-6. arterial blood pressure trait not specified 105.0 days 15 177.0 mmHg 1.03 4.0 tail cuff plethysmography 0.0 64882 301
SHR.F344-(D12Mgh5-D12Mgh6)/Snk systolic blood pressure control condition Ohno Y, et al., Am J Hypertens. 2007 Feb;20(2):172-6. arterial blood pressure trait not specified 105.0 days 10 166.0 mmHg 2.53 8.0 tail cuff plethysmography 0 64883 301
SS/NEisSlc systolic blood pressure controlled sodium content diet (8 %) (for 28 days) then adrenalectomy then controlled sodium content diet (0.3 %) (for 28 days) and dexamethasone (20 ug/d) Kitada K, et al., PLoS One. 2012;7(7):e41896. Epub 2012 Jul 24. arterial blood pressure trait male 98.0 days 4 141.0 mmHg 8.0 16.0 tail cuff plethysmography 0.0 69688 736
SHRSP/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 31 107.0 mmHg 1.26 7.0 tail cuff plethysmography 0.0 69161 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 33 148.0 mmHg 3.13 18.0 tail cuff plethysmography 0.0 69166 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 31 206.0 mmHg 1.44 8.0 tail cuff plethysmography 0.0 69177 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 28 199.0 mmHg 1.89 10.0 tail cuff plethysmography 0.0 69184 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 30 195.0 mmHg 1.46 8.0 tail cuff plethysmography 0.0 69183 1126
SHRSP.SHRSR-(Klk1-D1Mit3)/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 31 106.0 mmHg 0.18 1.0 tail cuff plethysmography 0.0 69191 1126
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 220.0 mmHg 5.6 tail cuff plethysmography 0.0 restrained, 28 degrees C 70581 1482
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 207.0 mmHg 4.7 21.02 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65305 565
SS.LEW-(D1Mco2-D1Mco35)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 39 serial mean 181.0 mmHg 1.3 8.12 tail cuff plethysmography tail 0 64734 222
SS.LEW-(D17Mco3-D17Mco10)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 20 serial mean 210.0 mmHg 3.7 16.55 tail cuff plethysmography tail 0 64742 222
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 131.0 days-134.0 days 11 data obtained at three consistent sessions per day serial mean 209.0 mmHg tail cuff plethysmography 345600 65964 650
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (4 %) (between 24 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 65.0 days-68.0 days 22 data obtained at three consistent sessions per day serial mean 238.0 mmHg tail cuff plethysmography 345600 66027 650
SS.SR-(Syt2-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait not specified 65.0 days-68.0 days 25 data obtained at three consistent sessions per day serial mean 219.0 mmHg tail cuff plethysmography 345600 66030 650
SR/Hsd mean arterial blood pressure controlled sodium content diet (4 %) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 110.0 mmHg 4.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67234 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -30.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67237 731
SS.LEW-(D5Mco39-D5Mco57)(D5Mco42-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 226.0 mmHg 5.5 tail cuff plethysmography 0.0 restrained, 28 degrees C 70586 1482
SS.LEW-(D5Mco41-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 204.0 mmHg 5.4 tail cuff plethysmography 0.0 restrained, 28 degrees C 70591 1482
SS.LEW-(D5Mco39-D5Mco41)(D5Mco42-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 157.0 mmHg 4.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70595 1482
SS.LEW-(D5Mco42-D5Mco47)/2Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 187.0 mmHg 5.2 tail cuff plethysmography 0.0 restrained, 28 degrees C 70593 1482
SHRSP.WKY-(D1Smu13-D1Wox33)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 10 serial mean 205.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements for SPwch1.72 68744 990
Crl:SD systolic blood pressure controlled fructose content diet (66 %) (between 14 and 28 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. arterial blood pressure trait male  days 160.0 mmHg 3.0 tail cuff plethysmography tail 0.0 F 75925 1540
SS.LEW-(D1Mco134-D1Wox6)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 155.0 mmHg 16.0 87.64 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96945 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 217.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96983 1778
SHR-Ndufc2em2Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 26 undefined 177.0 mmHg 1.37 7.0 tail cuff plethysmography 0.0 97925 1938
LH/Mav systolic blood pressure vehicle control condition Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. arterial blood pressure trait male 84.0 days 8 undefined 160.0 mmHg tail cuff plethysmography 0.0 102849 2761
LH/Mav systolic blood pressure vehicle control condition Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. arterial blood pressure trait male 63.0 days 8 undefined 160.0 mmHg 3.0 8.49 tail cuff plethysmography 0.0 102848 2761
LH/Mav systolic blood pressure hydralazine (75 mg/kg/d) (for 42 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 42 days) and reserpine (0.75 mg/kg/d) (for 42 days) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. arterial blood pressure trait male 63.0 days 10 undefined 133.0 mmHg 2.0 6.32 tail cuff plethysmography 0.0 102852 2761
SR heart rate controlled sodium content diet (0.3 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart pumping trait male 42.0 days 5 413.0 beats/min 10.73 24.0 tail cuff plethysmography 0.0 103279 2803
SS systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 42.0 days 5 113.0 mmHg 2.24 5.0 tail cuff plethysmography 0.0 103284 2803
SR systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 84.0 days 6 115.0 mmHg 4.9 12.0 tail cuff plethysmography 0.0 103287 2803
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77.0 days 14 mean of 3 samples of undefined duration serial mean 173.0 mmHg 2.67 10.0 tail cuff plethysmography 0.0 102466 2689
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 77.0 days 10 undefined 233.0 mmHg 0.63 2.0 tail cuff plethysmography 0.0 102494 2690
SR systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 126.0 days 6 122.0 mmHg 5.31 13.0 tail cuff plethysmography 0.0 103289 2803
LH/Mav systolic blood pressure controlled perindopril content drinking water (3 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 84.0 days 12 between 9a-1p 97.0 mmHg 3.0 10.39 tail cuff plethysmography 0.0 103435 2825
SHR systolic blood pressure control condition (for 0 hours) Cerutti C, et al., Physiol Genomics. 2006 Nov 27;27(3):295-308. doi: 10.1152/physiolgenomics.00318.2005. Epub 2006 Aug 1. arterial blood pressure trait male 84.0 days 5 207.0 mmHg 8.0 17.89 tail cuff plethysmography 0.0 103471 2826
WF/Mol systolic blood pressure controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 90.0 mmHg 6.0 14.7 tail cuff plethysmography 0.0 acf 4 days 101344 2585
MW systolic blood pressure right nephrectomy (for 84 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 6 undefined 190.0 mmHg 10.0 24.49 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 84 days 100869 2523
MW systolic blood pressure right nephrectomy (for 84 days) then enalapril (20 mg/kg/d) (for 28 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 9 undefined 141.3 mmHg 6.4 19.2 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 84 days 100872 2523
MW systolic blood pressure right nephrectomy (for 84 days) then captopril (30 mg/kg/d) (for 28 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 131.0 mmHg 3.9 12.33 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 84 days 100871 2523
MW systolic blood pressure right nephrectomy (for 84 days) then angiotensin II receptor antagonist (20 mg/l) (for 28 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 7 undefined 157.1 mmHg 15.3 40.48 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 84 days 100874 2523
MW systolic blood pressure right nephrectomy (for 112 days) then enalapril (20 mg/kg/d) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 9 undefined 140.6 mmHg 5.3 15.9 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 112 days 100878 2523
MW systolic blood pressure right nephrectomy (for 112 days) then captopril (30 mg/kg/d) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 135.0 mmHg 6.4 20.24 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 112 days 100877 2523
MW systolic blood pressure right nephrectomy (for 112 days) then lisinopril (10 mg/kg/d) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 135.0 mmHg 4.5 14.23 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 112 days 100879 2523
MW systolic blood pressure right nephrectomy (for 112 days) then reserpine (5 mg/l) (for 56 days) and hydralazine (80 mg/l) (for 56 days) and controlled hydralazine content drinking water (25 mg/l) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 149.4 mmHg 8.3 26.25 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 112 days 100880 2523
MW systolic blood pressure doxorubicin (2 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 7 undefined 118.0 mmHg 3.0 7.94 tail cuff plethysmography 0.0 doxorubicin days 101161 2581
MW systolic blood pressure unilateral nephrectomy (for 14 days) then vehicle control condition Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 7 undefined 118.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 unx 14 days 101159 2581
SD systolic blood pressure unilateral nephrectomy (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 7 undefined 212.0 mmHg 7.56 20.0 tail cuff plethysmography 0.0 unx 28 days 101584 2602
SD systolic blood pressure unilateral nephrectomy (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 8 undefined 208.0 mmHg 6.01 17.0 tail cuff plethysmography 0.0 unx 28 days 101617 2602
WF/Mol systolic blood pressure vehicle control condition then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 7 undefined 116.0 mmHg 4.0 10.58 tail cuff plethysmography 0.0 acf 7 days 101350 2585
WF/Mol systolic blood pressure controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 129.0 mmHg 6.0 13.42 tail cuff plethysmography 0.0 sham acf 7 days 101349 2585
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 130.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 sham acf 7 days 101351 2585
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 8 undefined 104.0 mmHg 7.0 19.8 tail cuff plethysmography 0.0 acf 4 days 101358 2585
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 143.0 mmHg 5.0 12.25 tail cuff plethysmography 0.0 sham acf 4 days 101359 2585
WF/Mol heart rate vehicle control condition then sham surgical control condition (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 406.0 beats/min 22.0 49.19 tail cuff plethysmography 0.0 sham acf 4 days 101369 2585
SS-Nppbem2Mcwi-/- diastolic blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 252.0 days 6 serial mean 149.0 mmHg 30.0 73.48 tail cuff plethysmography 0.0 99827 2319
SS-Nppbem2Mcwi-/- systolic blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 252.0 days 6 serial mean 201.0 mmHg 17.0 41.64 tail cuff plethysmography 0.0 99833 2319
SS-Nppbem2Mcwi-/- mean arterial blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 252.0 days 6 serial mean 167.0 mmHg 25.0 61.24 tail cuff plethysmography 0.0 99839 2319
SD mean arterial blood pressure left nephrectomy (for 70 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 137.0 mmHg 3.0 7.94 tail cuff plethysmography 0.0 unx 70 days 98949 2179
SD systolic blood pressure streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. arterial blood pressure trait male  days 8 undefined 128.0 mmHg 1.06 3.0 tail cuff plethysmography 0.0 stz 154 days 99900 2358
SDT/Jcl systolic blood pressure nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 6 serial mean 131.1 mmHg 5.9 14.45 tail cuff plethysmography 0.0 unx 84 days 100117 2419
SD systolic blood pressure nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled calcium content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. arterial blood pressure trait male 140.0 days 8 serial mean 134.3 mmHg 13.2 37.34 tail cuff plethysmography 0.0 unx 84 days 100116 2419
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 70.0 days 8 396.0 beats/min 12.73 36.0 tail cuff plethysmography 0.0 102413 2689
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 77.0 days 7 377.0 beats/min 8.32 22.0 tail cuff plethysmography 0.0 102415 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 77.0 days 7 mean of 3 samples of undefined duration serial mean 125.0 mmHg 3.02 8.0 tail cuff plethysmography 0.0 102433 2689
MWF/ZtmRrrc mean arterial blood pressure enalapril (50 mg/l) (for 60 days) Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 126.0 days 10 undefined 110.0 mmHg 1.9 6.0 tail cuff plethysmography 0.0 100916 2541
MWF/ZtmRrrc mean arterial blood pressure control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 126.0 days 7 undefined 136.0 mmHg 3.78 10.0 tail cuff plethysmography 0.0 100917 2541
WKY systolic blood pressure 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 9 108.0 mmHg 3.0 9.0 tail cuff plethysmography 0.0 100451 2479
SD systolic blood pressure sham surgical control condition (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. arterial blood pressure trait male 77.0 days 6 undefined 134.0 mmHg 2.0 4.9 tail cuff plethysmography 0.0 sham lad occlusion 28 days 101088 2564
SS.ZUC-Leprfa-/-/Slc systolic blood pressure bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. arterial blood pressure trait female 91.0 days 7 undefined 202.0 mmHg 6.0 15.87 tail cuff plethysmography 0.0 ovariectomy 42 days 101672 2622
SS-Leprem2Mcwi systolic blood pressure physical restraint (20-30 min/d) (for 4 days) McPherson KC, et al., Am J Physiol Renal Physiol. 2016 Oct 1;311(4):F793-F804. doi: 10.1152/ajprenal.00590.2015. Epub 2016 Jul 27. arterial blood pressure trait male 126.0 days 13 201.0 mmHg 10.0 36.06 tail cuff plethysmography 0.0 100080 2418
PCK-Pkhd1pck/CrljCrl systolic blood pressure controlled losartan content drinking water (5 mg/kg/d) (for 10 days) Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 70.0 days 3 mean of 3 samples - 1 per minute serial mean 123.0 mmHg 0.58 1.0 tail cuff plethysmography 0.0 100187 2439
SD systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 60.0 days 5 mean of 3 samples - 1 per minute serial mean 123.0 mmHg 2.68 6.0 tail cuff plethysmography 0.0 100168 2439
OLETF diastolic blood pressure control condition (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 12 undefined 117.3 mmHg 4.9 16.97 tail cuff plethysmography 0.0 99426 2298
OLETF diastolic blood pressure olmesartan medoxomil (0.35 mg/kg/d) (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 11 undefined 112.6 mmHg 4.7 15.59 tail cuff plethysmography 0.0 99427 2298
OLETF systolic blood pressure temocapril (3.9 mg/kg/d) (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 11 undefined 124.0 mmHg 3.2 10.61 tail cuff plethysmography 0.0 99424 2298
MW systolic blood pressure right nephrectomy (for 56 days) then angiotensin II receptor antagonist (80 mg/l) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 5 undefined 207.0 mmHg 17.7 39.58 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 56 days 100868 2523
WI systolic blood pressure controlled in utero environment (for 21 days) and standard diet (50 % of calories) (for 21 days) Ceravolo GS, et al., Life Sci. 2007 Jan 30;80(8):782-7. Epub 2006 Nov 10. arterial blood pressure trait male 102.0 days 35 mean of 3 samples of undefined duration serial mean 135.7 mmHg 0.35 2.07 tail cuff plethysmography 0.0 101056 2563
WI diastolic blood pressure swimming with water weights (for 1 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. arterial blood pressure trait female  days 16 30 min mean continuous mean 95.8 mmHg 1.33 5.3 tail cuff plethysmography 1800.0 swim 1 days following 8 wk protocol 98741 2159
Crl:WI systolic blood pressure control condition (for 730 days) Ruiz-Torres MP, et al., J Am Soc Nephrol. 1998 May;9(5):782-91. arterial blood pressure trait male 730.0 days 10 143.0 mmHg 9.0 28.46 tail cuff plethysmography 0.0 101284 2584
Crl:WI systolic blood pressure control condition (for 912 days) Ruiz-Torres MP, et al., J Am Soc Nephrol. 1998 May;9(5):782-91. arterial blood pressure trait male 912.0 days 10 151.0 mmHg 9.0 28.46 tail cuff plethysmography 0.0 101285 2584
SS.ZUC-Leprfa+/+/Slc systolic blood pressure control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. arterial blood pressure trait male 126.0 days 6 137.7 mmHg 3.04 7.45 tail cuff plethysmography 0.0 101889 2642
SS.ZUC-Leprfa+/+/Slc heart rate control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. heart pumping trait male 126.0 days 6 417.32 beats/min 13.71 33.58 tail cuff plethysmography 0.0 101891 2642
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 276.0 days-280.0 days 5 49.0 mmHg 2.0 4.47 tail cuff plethysmography 0.0 n=5-7, change between age 9months and 10 months 106742 3039
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 276.0 days-280.0 days 5 -3.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 9months and 10 months 106741 3039
SBH/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) then controlled sodium content drinking water (1 %) (for 28 days) and deoxycorticosterone acetate (25 mg) (for 28 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 70.0 days 5 195.0 mmHg 3.0 6.71 tail cuff plethysmography 0.0 106753 3039
SBN/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 42.0 days 16 121.0 mmHg 2.0 8.0 tail cuff plethysmography 0.0 106750 3039
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (between 24 and 28 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 360.0 days-364.0 days 5 0.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 12months and 13 months 106744 3039
SBH/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 42.0 days 5 137.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 106752 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (between 24 and 28 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 192.0 days-196.0 days 5 46.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 n=5-7, change between age 6 months and 7 months 106739 3039
Crl:WI systolic blood pressure vehicle control condition (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 126.9 mmHg 4.0 12.65 tail cuff plethysmography 0.0 109407 3140
MWF/FubRkb systolic blood pressure vehicle control condition (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 151.5 mmHg 9.0 28.46 tail cuff plethysmography 0.0 109409 3140
Crl:WI systolic blood pressure finerenone (10 mg/kg/d) (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. arterial blood pressure trait male 112.0 days 10 127.5 mmHg 5.0 15.81 tail cuff plethysmography 0.0 109408 3140
Crl:WI heart rate vehicle control condition (for 28 days) Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. heart pumping trait male 112.0 days 10 355.3 beats/min 9.7 30.67 tail cuff plethysmography heart 0.0 109411 3140
MWF/Ztm systolic blood pressure control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 280.0 days 7 197.0 mmHg 4.91 13.0 tail cuff plethysmography 0.0 109522 3147
MWF/Ztm systolic blood pressure control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 420.0 days 7 213.0 mmHg 4.16 11.0 tail cuff plethysmography 0.0 109524 3147
SHR systolic blood pressure diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 143.18 mmHg 9.25 24.48 tail cuff plethysmography 90 min 0.1% methylcellulose per os 108288 3101
WAG systolic blood pressure diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 126.98 mmHg 5.71 15.11 tail cuff plethysmography 120 min 0.1% methylcellulose per os 108291 3101
SHR systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 162.67 mmHg 1.61 4.27 tail cuff plethysmography 108302 3101
WAG systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 121.17 mmHg 1.36 3.6 tail cuff plethysmography 108305 3101
WAG systolic blood pressure estrus Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 134.0 mmHg 4.62 12.22 tail cuff plethysmography 108309 3101
SHR systolic blood pressure estrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 160.29 mmHg 2.08 5.5 tail cuff plethysmography 108312 3101
WAG systolic blood pressure estrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 131.43 mmHg 2.73 7.23 tail cuff plethysmography 108311 3101
WAG systolic blood pressure estrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 123.0 mmHg 0.98 2.58 tail cuff plethysmography 108315 3101
SHR systolic blood pressure estrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 161.86 mmHg 1.49 3.93 tail cuff plethysmography 108316 3101
SHR systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 162.14 mmHg 1.74 4.6 tail cuff plethysmography 108328 3101
WAG systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 121.29 mmHg 1.44 3.82 tail cuff plethysmography 108327 3101
WAG systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 129.57 mmHg 2.54 6.73 tail cuff plethysmography 108343 3101
WKY systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 125.3 mmHg 0.68 1.8 tail cuff plethysmography 108357 3101
SHR systolic blood pressure diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 155.11 mmHg 9.41 24.89 tail cuff plethysmography 60 min 0.1% methylcellulose per os 108366 3101
Crl:SD systolic blood pressure controlled protein content diet (20 %) then water (for 120 days) Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6. arterial blood pressure trait male 540.0 days-660.0 days 9 168.0 mmHg 6.0 18.0 tail cuff plethysmography tail 0.0 108593 3126
ISIAH systolic blood pressure physical restraint in tube type rodent restrainer (for 0.5 hours) Markel AL, et al., J Endocrinol. 2007 Dec;195(3):439-50. doi: 10.1677/JOE-07-0254. arterial blood pressure trait male 120.0 days-150.0 days 27 198.0 mmHg 4.0 20.78 tail cuff plethysmography 0.0 restraint 30 min 108639 3127
GK/MolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 240.0 days 11 124.0 mmHg 3.0 9.95 tail cuff plethysmography 0.0 10 consecutive measurements 106930 3071
GK/MolTac mean arterial blood pressure control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. arterial blood pressure trait male 112.0 days 118.0 mmHg 1.0 tail cuff plethysmography 0.0 108031 3109
WKY/NCrl systolic blood pressure control condition Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. arterial blood pressure trait male 84.0 days 10 139.0 mmHg 5.0 15.81 tail cuff plethysmography 0.0 109281 3141
MWF/FubRkb systolic blood pressure control condition Rothermund L, etal., J Hypertens. 2006 Sep 24(9). arterial blood pressure trait male 100.0 days 10 159.0 mmHg 6.0 18.97 tail cuff plethysmography 0.0 108098 3115
SHRSP/A3N systolic blood pressure controlled hydralazine content drinking water (100 mg/l) (for 60 days) and controlled hydrochlorothiazide content drinking water (100 mg/l) (for 60 days) then controlled hydralazine content drinking water (200 mg/l) (for 60 days) and controlled hydrochlorothiazide content drinking water (200 mg/l) (for 60 days) Furspan PB, etal., J Hypertens. 1987 Jun;5(3):293-7. doi: 10.1097/00004872-198706000-00005. arterial blood pressure trait both 141.0 days 6 131.0 mmHg 5.6 13.72 tail cuff plethysmography 0.0 107639 3094
SHRSP/A3N heart rate controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) and controlled carvedilol content diet (2400 ppm) (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. heart pumping trait male 203.0 days-224.0 days 10 280.0 beats/min 4.0 12.65 tail cuff plethysmography 0.0 high salt high fat diet +carvedilol 107116 3075
MWF/Fub systolic blood pressure standard diet Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. arterial blood pressure trait female 100.0 days-103.0 days 8 156.0 mmHg 3.0 8.49 tail cuff plethysmography tail 0.0 109020 3134
WKY systolic blood pressure control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 280.0 days 4 135.0 mmHg 3.5 7.0 tail cuff plethysmography 0.0 109528 3147
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 191.0 mmHg 3.5 15.65 tail cuff plethysmography 0 average of 4days 65481 611
SS.LEW-(D1Mco8-D1Rat213)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 183.0 mmHg 3.0 13.42 tail cuff plethysmography 0 average of 4days 65486 611
SS.LEW-(D1Uia8-D1Rat211)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 207.0 mmHg 5.8 25.94 tail cuff plethysmography 0 average of 4days 65485 611
SS.LEW-(D1Mco4-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 178.0 mmHg 2.3 10.29 tail cuff plethysmography 0 average of 4days 65489 611
SHR.WKY-(D1Got158-D1Got161)/Njs systolic blood pressure control condition Clemitson JR, et al., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1. arterial blood pressure trait male 140.0 days-142.0 days 17 183.0 mmHg 0.17 0.7 tail cuff plethysmography 65256 564
SS.LEW-(D1Mco102-D1Mco129)/2Mco systolic blood pressure controlled sodium content diet (0.4 %) (between 36 and 40 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 66.0 days-70.0 days 20 serial mean 176.0 mmHg 2.2 9.84 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65311 565
WKY.SHR-(D1Wox19-D1Mit2)/Njs mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 112.0 days 29 continuous mean 127.3 mmHg 1.6 8.6 tail cuff plethysmography 0 animals were prewarmed to 34 degrees C for 20 min before BP 65081 206
SHR.WKY-(D1Wox19-D1Wox34)/Njs mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 112.0 days 31 continuous mean 186.5 mmHg 2.57 14.3 tail cuff plethysmography 0 animals were prewarmed to 34 degrees C for 20 min before BP 65083 206
SHR mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 112.0 days 28 continuous mean 195.7 mmHg 2.48 13.1 tail cuff plethysmography 0 animals were prewarmed to 34 degrees C for 20 min before BP 65082 206
WKY.SHR-(D1Wox19-D1Mit2)/Njs mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 140.0 days 29 continuous mean 133.4 mmHg 1.39 7.5 tail cuff plethysmography animals were prewarmed to 34 degrees C for 20 min before BP 65085 206
SHR mean arterial blood pressure control condition Frantz SA, et al., Hypertension 1998 Oct;32(4):639-46 arterial blood pressure trait male 140.0 days 28 continuous mean 206.8 mmHg 2.36 12.5 tail cuff plethysmography animals were prewarmed to 34 degrees C for 20 min before BP 65086 206
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 20 serial mean 199.3 mmHg 7.5 33.54 tail cuff plethysmography 11787 146
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 42 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 79.0 days 20 serial mean 231.4 mmHg 7.2 32.2 tail cuff plethysmography 11789 146
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 224.9 mmHg 4.8 21.47 tail cuff plethysmography average of 12 readings from 4 daily sessions 11795 147
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 243.4 mmHg 4.0 17.89 tail cuff plethysmography average of 12 readings from 4 daily sessions 11801 147
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 235.1 mmHg 4.6 20.57 tail cuff plethysmography average of 12 readings from 4 daily sessions 11813 147
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 205.0 mmHg 2.9 12.97 tail cuff plethysmography average of 12 readings from 4 daily sessions 11837 148
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 41 serial mean 205.0 mmHg 2.6 16.65 tail cuff plethysmography average of 12 readings from 4 daily sessions 11841 148
SS.WKY-(D2N35-Mme)/Mco systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 185.0 mmHg 1.8 8.82 tail cuff plethysmography 11846 150
SS.MNS-(D10M11Mit119-D10Mit11)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 178.0 mmHg 1.9 9.31 tail cuff plethysmography 11847 150
SS.MNS-(Aldoc-D10Mco1)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 38 serial mean 210.0 mmHg 2.7 16.64 tail cuff plethysmography average of 12 readings from 4 daily sessions 11842 148
SS.WKY-(D2N35-Mme),MNS-(D10Mit11-D10M11Mit119)/Mco systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 170.0 mmHg 1.4 6.86 tail cuff plethysmography 11848 150
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 209.0 mmHg 3.51 15.7 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12128 232
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 210.0 mmHg 4.6 20.57 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12130 232
SS.MNS-(D10Mco30-D10Got91)/3Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 193.0 mmHg 3.5 15.65 tail cuff plethysmography tail 345600.0 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12140 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 10 serial mean 150.0 mmHg 2.3 7.27 tail cuff plethysmography tail 0 12169 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 8 serial mean 131.0 mmHg 3.3 9.33 tail cuff plethysmography tail 0 12174 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 10 serial mean 156.0 mmHg 4.0 12.65 tail cuff plethysmography tail 0 12170 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 8 serial mean 140.0 mmHg 2.5 7.07 tail cuff plethysmography tail 0 12178 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 8 serial mean 152.0 mmHg 4.5 12.73 tail cuff plethysmography tail 0 12176 222
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 197.0 mmHg 3.74 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11907 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 198.0 mmHg 3.62 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11912 205
SS.LEW-(D10Mco84-D10Mco129)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 213.0 mmHg 5.37 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11919 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 235.0 mmHg 4.8 21.47 tail cuff plethysmography average of 3-4 consistent readings 12456 266
SS.LEW-(D1Mco36-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 188.0 mmHg 3.08 13.77 tail cuff plethysmography average of 3-4 consistent readings 12463 266
SS.LEW-(D1Uia8-D1Mco38)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 205.0 mmHg 1.76 7.87 tail cuff plethysmography average of 3-4 consistent readings 12470 266
SHR/Izm systolic blood pressure controlled fat content diet (5 %) (for 63 days) and controlled potassium content diet (0.75 %) Watanabe T, et al., Biochem Biophys Res Commun 2005 Apr 15;329(3):879-87. arterial blood pressure trait male 91.0 days 10 185.9 mmHg 2.09 6.6 tail cuff plethysmography 13276 263
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 197.0 mmHg 3.53 tail cuff plethysmography 0.0 67511 749
SS.SHR-(D9Mco72-D9Mco109)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 188.0 mmHg 3.21 tail cuff plethysmography 0.0 67514 749
SS.SHR-(D9Mco72-D9Mco105)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 207.0 mmHg 3.5 tail cuff plethysmography 0.0 67518 749
SS.SHR-(D9Rat7-D9Mco91)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 208.0 mmHg 5.78 tail cuff plethysmography 0.0 67525 749
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 19 serial mean 190.9 mmHg 3.6 15.69 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65800 237
SHR/NHsd systolic blood pressure controlled sodium content diet (4 %) (for 14 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 67.0 days 10 179.0 mmHg 5.0 15.81 tail cuff plethysmography 0 66118 691
SS/Jr systolic blood pressure controlled sodium content diet (4 %) (for 28 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 81.0 days 10 238.0 mmHg 7.0 22.14 tail cuff plethysmography 0 66119 691
SS/JrSeac systolic blood pressure controlled sodium content diet (0.3 %) (for 35 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 77.0 days 5 125.0 mmHg 9.84 22.0 tail cuff plethysmography 0.0 67248 733
SS/JrSeac systolic blood pressure controlled sodium content diet (8 %) (for 84 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 126.0 days 5 249.0 mmHg 18.34 41.0 tail cuff plethysmography 0.0 67251 733
SS/JrSeac systolic blood pressure control condition Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 42.0 days 20 119.0 mmHg 3.13 14.0 tail cuff plethysmography 0.0 67252 733
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (0.15 %) then ruthenium red (3 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 7.0 mmHg 1.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67269 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then ruthenium red (3 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 15.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67270 731
SS/HsdMcwiCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then ruthenium red (3 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 4.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67272 731
SR/Hsd absolute change in mean arterial blood pressure controlled sodium content diet (4 %) then apamin (100 ug/kg) and charybdotoxin (100 ug/kg) and 4-alpha-phorbol 12,13-didecanoate (2.5 mg/kg) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days -13.0 mmHg 2.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67274 731
WKY/Izm systolic blood pressure control condition Kato N, et al., Hypertension 2003 DXCO;42(6):1191-7. arterial blood pressure trait male 91.0 days 5 131.8 mmHg 2.0 4.47 tail cuff plethysmography 11679 115
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 20 serial mean 219.0 mmHg 3.4 15.21 tail cuff plethysmography tail 0 64738 222
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 19 serial mean 205.0 mmHg 5.9 25.72 tail cuff plethysmography tail 0 64741 222
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 81.0 days-84.0 days 20 data obtained at three consistent sessions per day serial mean 231.0 mmHg tail cuff plethysmography 345600 65971 650
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 81.0 days-84.0 days 20 data obtained at three consistent sessions per day serial mean 208.0 mmHg tail cuff plethysmography 345600 65973 650
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait not specified 65.0 days-68.0 days 27 data obtained at three consistent sessions per day serial mean 211.0 mmHg tail cuff plethysmography 345600 66028 650
SS-Chr 2BN/Mcwi systolic blood pressure control condition Viel EC, et al., Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H938-44. Epub 2009 Dec 31. arterial blood pressure trait male 84.0 days 12 150.0 mmHg 3.0 10.39 tail cuff plethysmography 0.0 67228 730
SR/Hsd mean arterial blood pressure control condition (0.15 %) Gao F and Wang DH, Hypertension. 2010 Apr;55(4):1018-25. Epub 2010 Mar 1. arterial blood pressure trait male 35.0 days-56.0 days 106.0 mmHg 3.0 tail cuff plethysmography 0.0 DR strain is from Charles River Laboratory, Wilmington, MA 67233 731
SS.LEW-(D5Mco39-D5Mco57)(D5Mco43-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 181.0 mmHg 2.5 tail cuff plethysmography 0.0 restrained, 28 degrees C 70587 1482
SS.LEW-(D5Mco43-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 179.0 mmHg 3.2 tail cuff plethysmography 0.0 restrained, 28 degrees C 70594 1482
MWF-Chr 6SHR/Rkb systolic blood pressure control condition Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. arterial blood pressure trait female 168.0 days 20 139.0 mmHg 1.6 7.16 tail cuff plethysmography 0.0 68173 309
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 18 191.0 mmHg 3.02 12.8 tail cuff plethysmography 0.0 69128 1126
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 18 191.0 mmHg 1.65 7.0 tail cuff plethysmography 0.0 69129 1126
SHRSP.WKY-(D1Wox29-D1Arb21)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 14 serial mean 194.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements 68738 990
WKY.SHRSP-(D1Smu13-D1Smu11)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 16 serial mean 119.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements 68742 990
ISIAH systolic blood pressure physical restraint in mechanical restrainer (for 0.5 hours) Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. arterial blood pressure trait not specified 180.0 days 11 215.0 mmHg 5.9 19.57 tail cuff plethysmography 0.0 68065 835
WKY.SHRSP-(D1Wox29-D1Arb21)/Izm systolic blood pressure control condition Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. arterial blood pressure trait not specified 112.0 days 10 148.0 mmHg 1.77 5.6 tail cuff plethysmography 0.0 10 s every 5 min 68690 971
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 33 110.0 mmHg 0.61 3.5 tail cuff plethysmography 0.0 69165 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 33 192.0 mmHg 1.22 7.0 tail cuff plethysmography 0.0 69168 1126
SHRSP/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 5 201.0 mmHg 8.72 19.5 tail cuff plethysmography 0.0 69164 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 32 199.0 mmHg 1.77 10.0 tail cuff plethysmography 0.0 69169 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure control condition Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 42.0 days 31 112.0 mmHg 0.36 2.0 tail cuff plethysmography 0.0 69179 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 31 208.0 mmHg 1.44 8.0 tail cuff plethysmography 0.0 69178 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 144.0 mmHg 1.98 11.0 tail cuff plethysmography 0.0 69180 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 20 192.0 mmHg 1.57 7.0 tail cuff plethysmography 0.0 69189 1126
SHRSP.SHRSR-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 31 190.0 mmHg 0.9 5.0 tail cuff plethysmography 0.0 69193 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 35 188.0 mmHg 2.11 12.5 tail cuff plethysmography 0.0 69197 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 14 192.0 mmHg 1.6 6.0 tail cuff plethysmography 0.0 69199 1126
SS.LEW-(D5Mco39-D5Mco41)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 190.0 mmHg 5.6 tail cuff plethysmography 0.0 restrained, 28 degrees C 70584 1482
Crl:SD systolic blood pressure control condition Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. arterial blood pressure trait male 63.0 days-77.0 days 8 141.0 mmHg 2.0 5.66 tail cuff plethysmography tail 0.0 C 75852 1540
Crl:SD systolic blood pressure controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. arterial blood pressure trait male 63.0 days-77.0 days 10 143.0 mmHg 2.0 6.32 tail cuff plethysmography tail 0.0 FT 75853 1540
WKY/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 16 serial mean 118.0 mmHg tail cuff plethysmography 0.0 avg of 5 measurements for 84607 990
Crl:SD systolic blood pressure controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days) Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. arterial blood pressure trait male  days 8 158.0 mmHg 3.0 8.49 tail cuff plethysmography tail 0.0 FT 75926 1540
SHRSP.WKY-(D1Smu13-D1Wox33)/Izm systolic blood pressure control condition Xiao B, et al., J Hypertens. 2010 Nov 8. arterial blood pressure trait male 84.0 days 10 serial mean 205.0 mmHg 3.79 12.0 tail cuff plethysmography 0.0 avg of 5 measurements for 84621 990
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 198.0 mmHg 2.0 10.95 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96986 1778
SHR/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 18 undefined 189.0 mmHg 1.41 6.0 tail cuff plethysmography 0.0 97912 1938
SHR-Ndufc2em1Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 10 undefined 188.0 mmHg 0.63 2.0 tail cuff plethysmography 0.0 97918 1938
SHR-Ndufc2em1Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 17 undefined 182.0 mmHg 1.7 7.0 tail cuff plethysmography 0.0 97921 1938
SHR-Ndufc2em2Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 24 undefined 189.0 mmHg 0.41 2.0 tail cuff plethysmography 0.0 97926 1938
SD systolic blood pressure controlled enalapril content drinking water (5 mg/kg/d) (for 10 days) Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 130.0 days 1 mean of 3 samples - 1 per minute serial mean 117.0 mmHg tail cuff plethysmography 0.0 102814 2439
SR heart rate controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart pumping trait male 84.0 days 6 379.0 beats/min 23.68 58.0 tail cuff plethysmography 0.0 103281 2803
WKY mean arterial blood pressure controlled in utero environment (30 % of calories) (for 22 days) Riviere G, et al., Hypertension. 2005 Nov;46(5):1169-74. Epub 2005 Oct 3. arterial blood pressure trait male 112.0 days 6 undefined 79.0 mmHg 2.0 4.9 tail cuff plethysmography 0.0 101686 2218
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 126.0 days 10 undefined 135.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 102493 2690
SS/NEisSlc systolic blood pressure controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 84 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. arterial blood pressure trait male 126.0 days 10 undefined 249.0 mmHg 5.06 16.0 tail cuff plethysmography 0.0 102495 2690
SR/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77.0 days 10 464.0 beats/min 8.54 27.0 tail cuff plethysmography 0.0 102496 2690
SS/NEisSlc heart rate controlled sodium chloride content diet (0.3 %) (for 42 days) then controlled sodium chloride content diet (8 %) (for 35 days) then pentobarbital (20 mg/kg) Horinaka S, et al., Int J Cardiol. 2003 Sep;91(1):25-35. heart pumping trait male 77.0 days 10 334.0 beats/min 13.28 42.0 tail cuff plethysmography 0.0 102506 2690
LL/Mav systolic blood pressure streptozotocin (100 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 112.0 days 18 mean of 3 samples of undefined duration serial mean 123.0 mmHg 2.0 8.49 tail cuff plethysmography 0.0 102727 2721
LL/Mav systolic blood pressure vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. arterial blood pressure trait male 112.0 days 9 mean of 3 samples of undefined duration serial mean 119.0 mmHg 4.0 12.0 tail cuff plethysmography 0.0 102726 2721
MWF systolic blood pressure lisinopril (80-100 mg/l) Macconi D, et al., Am J Pathol. 2009 Mar;174(3):797-807. Epub 2009 Jan 22. arterial blood pressure trait male 280.0 days 10 undefined 170.0 mmHg 2.53 8.0 tail cuff plethysmography 0.0 100231 2459
WKY systolic blood pressure puromycin aminonucleoside (50 mg/kg) (for 70 days) then saralasin (0.3 mg/kg/hr) (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 5 118.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 PA IV 50mg/kg 70 days 100593 2479
LH/Mav systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 84.0 days 13 between 9a-1p 129.0 mmHg 2.0 7.21 tail cuff plethysmography 0.0 103433 2825
LL/Mav systolic blood pressure control condition (for 0 hours) Cerutti C, et al., Physiol Genomics. 2006 Nov 27;27(3):295-308. doi: 10.1152/physiolgenomics.00318.2005. Epub 2006 Aug 1. arterial blood pressure trait male 84.0 days 5 108.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 103472 2826
MW systolic blood pressure right nephrectomy (for 84 days) then angiotensin II receptor antagonist (80 mg/l) (for 28 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 5 undefined 150.0 mmHg 9.4 21.02 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 84 days 100875 2523
MW systolic blood pressure right nephrectomy (for 112 days) then angiotensin II receptor antagonist (20 mg/l) (for 56 days) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 7 undefined 148.6 mmHg 13.5 35.72 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 112 days 100882 2523
MW systolic blood pressure doxorubicin (2 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 7 undefined 127.0 mmHg 7.0 18.52 tail cuff plethysmography 0.0 doxorubicin 17 days 101165 2581
MW systolic blood pressure unilateral nephrectomy (for 70 days) then puromycin aminonucleoside (100 mg/kg) then puromycin aminonucleoside (40 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 6 undefined 122.0 mmHg 3.0 7.35 tail cuff plethysmography 0.0 unx 70 days 101167 2581
MW systolic blood pressure unilateral nephrectomy (for 70 days) then vehicle control condition Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 7 undefined 122.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 unx 70 days 101168 2581
MW systolic blood pressure unilateral nephrectomy (for 70 days) and captopril (500 mg/l) (for 70 days) then puromycin aminonucleoside (100 mg/kg) then puromycin aminonucleoside (40 mg/kg) Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. arterial blood pressure trait male  days 5 undefined 100.0 mmHg 4.0 8.94 tail cuff plethysmography 0.0 unx 70 days 101169 2581
SD systolic blood pressure unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 6 undefined 186.0 mmHg 10.61 26.0 tail cuff plethysmography 0.0 unx 28 days 101586 2602
SD systolic blood pressure unilateral nephrectomy (for 14 days) then spironolactone (5.56 mg/kg/d) (for 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. arterial blood pressure trait male  days 8 undefined 192.0 mmHg 7.07 20.0 tail cuff plethysmography 0.0 unx 14 days 101616 2602
WF/Mol systolic blood pressure vehicle control condition then sham surgical control condition (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 150.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 sham acf 2 days 101357 2585
WF/Mol systolic blood pressure vehicle control condition then artificial aortocaval fistula (for 9 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 7 undefined 130.0 mmHg 10.0 26.46 tail cuff plethysmography 0.0 acf 9 days 101353 2585
WF/Mol systolic blood pressure vehicle control condition then artificial aortocaval fistula (for 2 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 5 undefined 125.0 mmHg 10.0 22.36 tail cuff plethysmography 0.0 acf 2 days 101356 2585
WF/Mol systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 121.0 mmHg 4.0 9.8 tail cuff plethysmography 0.0 acf 7 days 101362 2585
WF/Mol systolic blood pressure vehicle control condition then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. arterial blood pressure trait male  days 6 undefined 122.0 mmHg 3.0 7.35 tail cuff plethysmography 0.0 acf 4 days 101360 2585
WF/Mol heart rate controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 5 450.0 beats/min 13.0 29.07 tail cuff plethysmography 0.0 acf 4 days 101366 2585
WF/Mol heart rate vehicle control condition then artificial aortocaval fistula (for 4 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 460.0 beats/min 9.0 22.05 tail cuff plethysmography 0.0 acf 4 days 101368 2585
WF/Mol heart rate controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 7 443.0 beats/min 6.0 15.87 tail cuff plethysmography 0.0 acf 7 days 101370 2585
SS-Nppbem2Mcwi-/- systolic blood pressure gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 84.0 days 6 serial mean 141.0 mmHg 12.0 29.39 tail cuff plethysmography 0.0 99829 2319
SS-Nppbem2Mcwi-/- systolic blood pressure vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. arterial blood pressure trait male 252.0 days 7 serial mean 197.0 mmHg 26.0 68.79 tail cuff plethysmography 0.0 99832 2319
LL/Mav systolic blood pressure vehicle control condition Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. arterial blood pressure trait male 49.0 days-56.0 days 13 undefined 115.0 mmHg 3.0 10.82 tail cuff plethysmography 0.0 102644 2703
SD mean arterial blood pressure left nephrectomy then puromycin (100 mg/kg) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 115.0 mmHg 2.0 5.29 tail cuff plethysmography 0.0 unx 98938 2179
SD mean arterial blood pressure left nephrectomy (for 28 days) then puromycin (100 mg/kg) then anti-transforming growth factor beta antibody (0.5 mg/kg) then puromycin (80 mg/kg) Ma LJ, et al., Kidney Int. 2004 Jan;65(1):106-15. arterial blood pressure trait male  days 7 148.0 mmHg 4.0 10.58 tail cuff plethysmography 0.0 unx 28 days 98943 2179
SD systolic blood pressure control condition Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. arterial blood pressure trait male  days 8 undefined 127.0 mmHg 1.06 3.0 tail cuff plethysmography 0.0 99901 2358
SR/NEisSlc systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. arterial blood pressure trait male 126.0 days 8 undefined 138.0 mmHg 5.0 14.14 tail cuff plethysmography 0.0 102313 2684
WF/Mol heart rate vehicle control condition then artificial aortocaval fistula (for 7 days) Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. heart pumping trait male  days 6 448.0 beats/min 7.0 17.15 tail cuff plethysmography 0.0 acf 7 days 101387 2585
SR/NEisSlc heart rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. heart pumping trait male 63.0 days 7 389.0 beats/min 9.07 24.0 tail cuff plethysmography 0.0 102411 2689
SR/NEisSlc systolic blood pressure controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. arterial blood pressure trait male 63.0 days 7 mean of 3 samples of undefined duration serial mean 119.0 mmHg 3.02 8.0 tail cuff plethysmography 0.0 102429 2689
WKY systolic blood pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 7 112.0 mmHg 5.0 13.23 tail cuff plethysmography 0.0 PA IV 50mg/kg 15 days 100446 2479
WKY systolic blood pressure controlled enalapril content drinking water (50 mg/l) (for 497 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. arterial blood pressure trait male  days 9 96.0 mmHg 2.0 6.0 tail cuff plethysmography 0.0 PA IV 50mg/kg 490 days 100453 2479
SD systolic blood pressure left anterior descending coronary artery occlusion (for 28 days) Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7. arterial blood pressure trait male 77.0 days 6 undefined 125.0 mmHg 3.0 7.35 tail cuff plethysmography 0.0 lad occlusion 28 days 101087 2564
SS.ZUC-Leprfa+/+/Slc systolic blood pressure bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. arterial blood pressure trait female 91.0 days 12 undefined 141.0 mmHg 4.0 13.86 tail cuff plethysmography 0.0 ovariectomy 42 days 101670 2622
SS.ZUC-Leprfa-/-/Slc systolic blood pressure bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. arterial blood pressure trait female 91.0 days 8 undefined 221.0 mmHg 5.0 14.14 tail cuff plethysmography 0.0 ovariectomy 42 days 101671 2622
SS/JrHsdMcwi systolic blood pressure physical restraint (20-30 min/d) (for 4 days) McPherson KC, et al., Am J Physiol Renal Physiol. 2016 Oct 1;311(4):F793-F804. doi: 10.1152/ajprenal.00590.2015. Epub 2016 Jul 27. arterial blood pressure trait male 126.0 days 16 155.0 mmHg 3.0 12.0 tail cuff plethysmography 0.0 100079 2418
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 120.0 days 5 mean of 3 samples - 1 per minute serial mean 145.0 mmHg 2.24 5.0 tail cuff plethysmography 0.0 100182 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 60.0 days 4 mean of 3 samples - 1 per minute serial mean 124.0 mmHg 1.0 2.0 tail cuff plethysmography 0.0 100184 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 60.0 days 3 mean of 3 samples - 1 per minute serial mean 126.0 mmHg 0.58 1.0 tail cuff plethysmography 0.0 100186 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 90.0 days 8 mean of 3 samples - 1 per minute serial mean 140.0 mmHg 2.83 8.0 tail cuff plethysmography 0.0 100169 2439
SD systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 90.0 days 4 mean of 3 samples - 1 per minute serial mean 133.0 mmHg 3.0 6.0 tail cuff plethysmography 0.0 100170 2439
SD systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 120.0 days 11 mean of 3 samples - 1 per minute serial mean 133.0 mmHg 1.81 6.0 tail cuff plethysmography 0.0 100172 2439
PCK-Pkhd1pck/CrljCrl systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 210.0 days 4 mean of 3 samples - 1 per minute serial mean 161.0 mmHg 3.0 6.0 tail cuff plethysmography 0.0 100175 2439
SD systolic blood pressure control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. arterial blood pressure trait male 210.0 days 5 mean of 3 samples - 1 per minute serial mean 136.0 mmHg 1.79 4.0 tail cuff plethysmography 0.0 100176 2439
WI mean arterial blood pressure swimming (for 0.2 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. arterial blood pressure trait female  days 16 30 min mean continuous mean 114.7 mmHg 1.7 6.8 tail cuff plethysmography 1800.0 following 8 wk protocol 98744 2159
WI heart rate swimming (for 0.2 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. heart pumping trait female  days 16 continuous mean 340.8 beats/min 2.88 11.5 tail cuff plethysmography 1800.0 following 8 wk protocol 98746 2159
OLETF systolic blood pressure control condition (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 12 undefined 153.4 mmHg 4.3 14.9 tail cuff plethysmography 0.0 99421 2298
LETO systolic blood pressure control condition (for 84 days) Koga K, et al., Mol Med. 2002 Oct;8(10):591-9. arterial blood pressure trait male 364.0 days 11 undefined 128.5 mmHg 4.7 15.59 tail cuff plethysmography 0.0 99425 2298
MW systolic blood pressure right nephrectomy (for 56 days) then enalapril (20 mg/kg/d) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 9 undefined 183.8 mmHg 5.1 15.3 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 56 days 100865 2523
MW systolic blood pressure right nephrectomy (for 56 days) then reserpine (5 mg/l) and hydralazine (80 mg/l) and controlled hydralazine content drinking water (25 mg/l) Kakinuma Y, et al., Kidney Int. 1992 Jul;42(1):46-55. arterial blood pressure trait male  days 10 undefined 180.6 mmHg 7.7 24.35 tail cuff plethysmography 0.0 ~5/6 to 7/8 nephrectomy 56 days 100863 2523
WI systolic blood pressure controlled in utero environment (for 21 days) and standard diet (100 % of calories) (for 21 days) Ceravolo GS, et al., Life Sci. 2007 Jan 30;80(8):782-7. Epub 2006 Nov 10. arterial blood pressure trait male 102.0 days 21 mean of 3 samples of undefined duration serial mean 119.0 mmHg 0.75 3.44 tail cuff plethysmography 0.0 101055 2563
WI systolic blood pressure swimming with water weights (for 1 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. arterial blood pressure trait female  days 16 30 min mean continuous mean 123.1 mmHg 1.7 6.8 tail cuff plethysmography 1800.0 swim 1 days following 8 wk protocol 98739 2159
WI mean arterial blood pressure swimming with water weights (for 1 hours) Ma Z, et al., Eur J Appl Physiol. 2013 Oct;113(10):2473-86. doi: 10.1007/s00421-013-2685-9. Epub 2013 Jun 28. arterial blood pressure trait female  days 16 30 min mean continuous mean 110.4 mmHg 1.53 6.1 tail cuff plethysmography 1800.0 swim 1 days following 8 wk protocol 98743 2159
SS-Adora2bem2Mcwi systolic blood pressure control condition (for 147 days) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. arterial blood pressure trait male 147.0 days 8 207.0 mmHg 7.0 19.8 tail cuff plethysmography 0.0 105860 3023
SBH/Ygl systolic blood pressure controlled sodium chloride content diet (0.65 %) (for 98 days) Landau D, et al., J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040. arterial blood pressure trait male 98.0 days 7 139.0 mmHg 1.0 2.65 tail cuff plethysmography 0.0 106696 3038
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (for 30 days) and deoxycorticosterone acetate (25 mg) (for 30 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 52.0 days-56.0 days 5 2.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 1month and 2 months 106728 3039
SBN/Ygl systolic blood pressure controlled exposure to a foster mother of a different strain within the same species. (for 30 days) then controlled sodium content drinking water (1 %) (for 28 days) and deoxycorticosterone acetate (25 mg) (for 28 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 70.0 days 12 128.0 mmHg 1.0 3.46 tail cuff plethysmography 0.0 106749 3039
SBH/Ygl systolic blood pressure control condition Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait female 28.0 days 5 139.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 106727 3039
SBH/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (between 24 and 28 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 360.0 days-364.0 days 5 52.0 mmHg 3.0 6.71 tail cuff plethysmography 0.0 n=5-7, change between age 12months and 13 months 106746 3039
SBN/Ygl absolute change in systolic blood pressure controlled sodium content drinking water (1 %) (between 24 and 28 days) and deoxycorticosterone acetate (75 mg) (for 90 days) then deoxycorticosterone acetate (75 mg) (for 90 days) Yagil Y and Yagil C, J Hypertens. 2000 Oct;18(10):1393-9. doi: 10.1097/00004872-200018100-00006. arterial blood pressure trait male 192.0 days-196.0 days 5 1.0 mmHg 1.0 2.24 tail cuff plethysmography 0.0 n=5-7, change between age 6 months and 7 months 106736 3039
MWF/Ztm systolic blood pressure standard diet Iordache BE, etal., J Am Soc Nephrol. 1994 Dec;5(6):1378-84. arterial blood pressure trait male 252.0 days-253.0 days 5 170.0 mmHg 3.58 8.0 tail cuff plethysmography tail 0.0 109144 3136
MWF/Ztm systolic blood pressure control condition Macconi D, etal., J Am Soc Nephrol. 2012 Sep;23(9):1496-505. doi: 10.1681/ASN.2011121144. Epub 2012 Jul 19. arterial blood pressure trait male 350.0 days 7 206.0 mmHg 5.67 15.0 tail cuff plethysmography 0.0 109523 3147
SHRSP/A3N systolic blood pressure control condition Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. arterial blood pressure trait female 120.0 days-140.0 days 24 230.0 mmHg 6.0 29.39 tail cuff plethysmography 0.0 107570 3093
SHRSP/A3N systolic blood pressure reproduction condition Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. arterial blood pressure trait male 120.0 days-140.0 days 10 147.0 mmHg 10.0 31.62 tail cuff plethysmography 0.0 107569 3093
SHRSP/A3N systolic blood pressure control condition Furspan PB, etal., J Hypertens. 1987 Jun;5(3):293-7. doi: 10.1097/00004872-198706000-00005. arterial blood pressure trait both 180.0 days-270.0 days 13 207.0 mmHg 25.2 90.86 tail cuff plethysmography 0.0 107637 3094
MWF/ZtmRrrc mean arterial blood pressure control condition Remuzzi A, et al., J Clin Invest. 1990 Feb;85(2):541-9. arterial blood pressure trait male 70.0 days 8 undefined 154.0 mmHg 1.41 4.0 tail cuff plethysmography 0.0 107646 2541
SHR systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 163.57 mmHg 8.15 21.55 tail cuff plethysmography 108284 3101
WAG systolic blood pressure control condition Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 137.8 mmHg 2.72 7.2 tail cuff plethysmography 108285 3101
SHR systolic blood pressure diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 155.93 mmHg 7.57 20.02 tail cuff plethysmography 180 min 0.1% methylcellulose per os 108294 3101
WAG systolic blood pressure diclofenac (40 mg/kg) (for 3 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 135.22 mmHg 4.92 13.02 tail cuff plethysmography 180 min 0.1% methylcellulose per os 108295 3101
WAG systolic blood pressure proestrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 118.33 mmHg 2.02 5.35 tail cuff plethysmography 108301 3101
SHR systolic blood pressure estrus then diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 164.0 mmHg 2.97 7.85 tail cuff plethysmography 108310 3101
WAG systolic blood pressure estrus then diclofenac (40 mg/kg) (for 1.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 119.0 mmHg 3.48 9.2 tail cuff plethysmography 108313 3101
WAG systolic blood pressure metestrus then diclofenac (40 mg/kg) (for 2.5 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 127.57 mmHg 0.72 1.9 tail cuff plethysmography 108329 3101
WAG systolic blood pressure diestrus then diclofenac (40 mg/kg) (for 2 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait female 90.0 days-120.0 days 7 119.0 mmHg 2.65 7.0 tail cuff plethysmography 108339 3101
WKY systolic blood pressure diclofenac (40 mg/kg) (for 1 hours) Romanowska K, et al., Acta Pol Pharm. 2008 Nov-Dec;65(6):723-9. arterial blood pressure trait male 90.0 days-120.0 days 7 122.9 mmHg 0.79 2.1 tail cuff plethysmography 60 min 0.1% methylcellulose per os 108367 3101
SHRSP/A3N systolic blood pressure control condition Furspan PB, etal., J Hypertens. 1987 Jun;5(3):293-7. doi: 10.1097/00004872-198706000-00005. arterial blood pressure trait both 141.0 days 7 194.0 mmHg 16.7 44.18 tail cuff plethysmography 0.0 107638 3094
MWF systolic blood pressure control condition Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. arterial blood pressure trait male 126.0 days-140.0 days 7 151.0 mmHg 3.78 10.0 tail cuff plethysmography 0.0 110006 3163
MWF systolic blood pressure cyclosporine A (50 mg/kg/d) (for 6 days) Fassi A, etal., Am J Kidney Dis. 1999 Feb;33(2):267-75. doi: 10.1016/s0272-6386(99)70299-4. arterial blood pressure trait male 132.0 days-146.0 days 6 145.0 mmHg 6.16 15.1 tail cuff plethysmography 0.0 110010 3163
GK/MolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 60.0 days 6 114.0 mmHg 0.09 0.22 tail cuff plethysmography 0.0 10 consecutive measurements 106929 3071
GK/MolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 420.0 days 11 116.0 mmHg 1.7 5.64 tail cuff plethysmography 0.0 10 consecutive measurements 106931 3071
WKY/NMolTac systolic blood pressure control condition Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. arterial blood pressure trait female 60.0 days 6 114.0 mmHg 0.7 1.71 tail cuff plethysmography 0.0 10 consecutive measurements 106932 3071
ISIAH systolic blood pressure ether (for 0.1 hours) Markel AL, et al., J Endocrinol. 2007 Dec;195(3):439-50. doi: 10.1677/JOE-07-0254. arterial blood pressure trait male 120.0 days-150.0 days 27 167.0 mmHg 3.0 15.59 tail cuff plethysmography 0.0 108637 3127
MWF/Ztm systolic blood pressure standard diet Remuzzi A, etal., Am J Kidney Dis. 1999 Oct;34(4):626-32. doi: 10.1016/S0272-6386(99)70385-9. arterial blood pressure trait male 140.0 days 10 150.0 mmHg 6.64 21.0 tail cuff plethysmography 0.0 109977 3162
MWF/Ztm systolic blood pressure standard diet Remuzzi A, etal., Am J Kidney Dis. 1999 Oct;34(4):626-32. doi: 10.1016/S0272-6386(99)70385-9. arterial blood pressure trait male 140.0 days 7 153.0 mmHg 5.67 15.0 tail cuff plethysmography 0.0 109978 3162
HanTac:WH mean arterial blood pressure control condition Kold-Petersen H, etal., J Vasc Res. 2012;49(3):267-78. doi: 10.1159/000335487. Epub 2012 Apr 11. arterial blood pressure trait male 154.0 days 122.0 mmHg 5.0 tail cuff plethysmography 0.0 108032 3109
MWF-Chr 8SHR/Rkb systolic blood pressure control condition Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384. arterial blood pressure trait male 84.0 days 10 155.9 mmHg 1.9 6.01 tail cuff plethysmography 0.0 109288 3141
SHRSP/A3N heart rate controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. heart pumping trait male 203.0 days-224.0 days 10 341.0 beats/min 20.0 63.25 tail cuff plethysmography 0.0 high salt high fat diet 107117 3075
SHRSP/A3N heart rate standard condition (for 126 days) Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. heart pumping trait male 203.0 days-224.0 days 10 364.0 beats/min 24.0 75.89 tail cuff plethysmography 0.0 standard rat chow 107118 3075
MWF/Fub systolic blood pressure controlled sodium chloride content diet (8 %) (for 56 days) Kreutz R, etal., J Hypertens. 2000 Jun;18(6):777-82. doi: 10.1097/00004872-200018060-00017. arterial blood pressure trait female 100.0 days-103.0 days 8 134.0 mmHg 3.0 8.49 tail cuff plethysmography tail 0.0 109022 3134