abnormal epigenetic regulation of gene expression +
abnormal fibroblast physiology +
abnormal germ cell physiology +
abnormal hepatoblast physiology +
abnormal intestinal goblet cell physiology
abnormal intracellular organelle physiology +
abnormal lipid oxidation +
abnormal neural crest cell physiology +
abnormal ossification involved in bone remodeling
abnormal osteoblast physiology +
any functional anomaly of a skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell