Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
Centrally nucleated skeletal muscle fibers (HP:0003687)
Annotations: Rat: (0) Mouse: (0) Human: (55) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
Abnormal muscle fiber protein expression +   
Abnormal muscle fiber-type distribution +   
Abnormal sarcomere morphology +   
Abnormality of skeletal muscle fiber size +   
Angulated muscle fibers  
Autophagic vacuoles  
Central core regions in muscle fibers  
Centrally nucleated skeletal muscle fibers  
An abnormality in which the nuclei of sarcomeres take on an abnormally central localization (or in which this feature is found in an increased proportion of muscle cells).
Deposits immunoreactive to beta-amyloid protein  
Fingerprint bodies 
Hypertrophied muscle fibers  
Increased endomysial connective tissue  
Motheaten muscle fibers  
Muscle fiber atrophy +   
Muscle fiber inclusion bodies +   
Muscle fiber necrosis  
Muscle fiber splitting  
Myelin-like whorls in vacuolated fibers 
Necklace skeletal muscle fibers  
Perifascicular muscle fiber atrophy 
Ragged-red muscle fibers  
Rimmed vacuoles  
Ring fibers 
Skeletal muscle autophagosome accumulation  
Spheroid bodies 

Synonyms
Exact Synonyms: Central nuclei ;   Centralised nuclei ;   Centralised sarcomeric nuclei ;   Centralized nuclei ;   Centralized sarcomeric nuclei ;   Centrally nucleated skeletal muscle fibres
Xrefs: UMLS:C1842170
Definition Sources: https://orcid.org/0000-0002-0736-9199, PMID:20181480

paths to the root