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Ontology Browser

Term:
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione (GO:0019243)
Annotations: Rat: (3) Mouse: (4) Human: (3) Chinchilla: (0) Bonobo: (0) Dog: (2) Squirrel: (0) Pig: (3)
Parent Terms Term With Siblings Child Terms
D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde 
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione  
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.

Synonyms
Exact Synonyms: D-lactate biosynthesis from methylglyoxal ;   D-lactate biosynthetic process from methylglyoxal ;   methylglyoxal breakdown to D-lactate ;   methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione ;   methylglyoxal degradation to D-lactate
Related Synonyms: glyoxalase system ;   methylglyoxal detoxification
Xrefs: MetaCyc:PWY-5386
Definition Sources: GOC:ai, GOC:dph, PMID:2198020

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.