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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
glyceryl-ether monooxygenase activity  
mandelate 4-monooxygenase activity 
phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity 
phenylalanine 4-monooxygenase activity  
Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
tryptophan 5-monooxygenase activity  
tyrosine 3-monooxygenase activity  

Synonyms
Exact Synonyms: phenylalanine hydroxylase activity
Related Synonyms: L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) ;   PAH activity ;   phenylalaninase activity ;   phenylalanine 4-hydroxylase activity
Xrefs: EC:1.14.16.1 ;   MetaCyc:RXN66-569 ;   RHEA:20273 ;   Reactome:R-HSA-5649483 "Defective PAH does not hydroxylate L-Phe to L-Tyr" ;   Reactome:R-HSA-71118 "PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr"
Definition Sources: PMID:4004813, RHEA:20273

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