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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1
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Accession:PW:0000585 term browser browse the term
Definition:Orexin/hypocretin signaling through receptor 1 couples to Galphaq class of G proteins. Orexin/hypocretin receptor 1 primarily binds orexin A. Orexin A and B are derived from prepro-orexin precursor.


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orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAQ G protein subunit alpha q ISO RGD PMID:12890892 RGD:1642020 NCBI chr 9:77,716,097...78,031,811
Ensembl chr 9:77,716,097...78,031,811 		JBrowse link
G HCRT hypocretin neuropeptide precursor ISO RGD PMID:12890892 RGD:1642020 NCBI chr17:42,184,060...42,185,452
Ensembl chr17:42,184,060...42,185,452 		JBrowse link
G HCRTR1 hypocretin receptor 1 ISO RGD PMID:12890892 RGD:1642020 NCBI chr 1:31,617,689...31,634,492
Ensembl chr 1:31,617,686...31,632,518 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    signaling pathway 2493
      hormone signaling pathway 563
        peptide and protein hormone signaling pathway 446
          orexin/hypocretin signaling pathway 6
            orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1 3
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