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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:adiponectin signaling pathway
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Accession:PW:0000563 term browser browse the term
Definition:Adiponectin signaling, by a hormone secreted by the adipose tissue, impacts on metabolic pathways such as glucose and lipid metabolism, possibly via activation of the AMPK pathway. Its deregulation has been linked to obesity, cardiovascular diseases, diabetes and metabolic syndrome.
Synonyms:related_synonym: adiponectin-activated signaling pathway

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adiponectin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:16823476 RGD:1642395 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391 		JBrowse link
G ADIPOR1 adiponectin receptor 1 ISO RGD PMID:16823476 RGD:1642395 NCBI chr25:26,445,993...26,462,346
Ensembl chr25:26,453,242...26,462,549 		JBrowse link
G ADIPOR2 adiponectin receptor 2 ISO RGD PMID:16823476 PMID:18755807 PMID:24797033 PMID:27220557 RGD:1642395 RGD:25824939 RGD:25824940 RGD:25824943 NCBI chr11:1,802,694...1,836,703
Ensembl chr11:1,738,026...1,837,060 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4028
    signaling pathway 1919
      hormone signaling pathway 377
        peptide and protein hormone signaling pathway 270
          adiponectin signaling pathway 3
            altered adiponectin signaling pathway 0
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