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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:growth hormone signaling pathway
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Accession:PW:0000562 term browser browse the term
Definition:The growth hormone signaling pathway is an important regulator of postnatal development. However, despite many years of research, the molecular mechanisms underlying its many actions are incompletely understood. It is believed that its actions involve direct and indirect routes. An example of the latter is the role the pathway plays in stimulating the production of insulin-like growth factor.
Synonyms:related_synonym: Growth hormone receptor signaling;   growth hormone receptor signaling pathway


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growth hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHR growth hormone receptor ISO See also reference RGD:1624962/PMID:11244571 RGD PMID:11064147 RGD:1624963 NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666
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G JAK2 Janus kinase 2 ISO See also reference RGD:1624962/PMID:11244571 RGD PMID:11064147 RGD:1624963 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710
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Path 1
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  pathway 4028
    signaling pathway 1919
      hormone signaling pathway 377
        peptide and protein hormone signaling pathway 270
          growth hormone signaling pathway 2
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