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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal spleen marginal zone macrophage morphology
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Accession:MP:0008240 term browser browse the term
Definition:any structural anomaly of the cells present in the splenic marginal zone and are involved in the recognition and clearance of material, such as pathogen-derived material, from the splenic circulation
Comment:Spleen marginal zone macrophage cells express the cell surface protein CD209b (also called Signr1), which is often detected with the ER-TR9 antibody.
Synonyms:exact_synonym: abnormal ER-TR9 positive cells;   abnormal splenic marginal zone macrophage morphology

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  mammalian phenotype 0
    hematopoietic system phenotype 0
      abnormal hematopoietic system morphology/development 0
        abnormal spleen morphology 0
          abnormal spleen white pulp morphology 0
            abnormal spleen marginal zone morphology 0
              abnormal spleen marginal zone macrophage morphology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    hematopoietic system phenotype 0
      abnormal hematopoietic system morphology/development 0
        abnormal hematopoietic cell morphology 0
          abnormal leukocyte morphology 0
            abnormal myeloid leukocyte morphology 0
              abnormal phagocyte morphology 0
                abnormal mononuclear phagocyte morphology 0
                  abnormal macrophage morphology 0
                    abnormal spleen marginal zone macrophage morphology 0
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