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ONTOLOGY REPORT - ANNOTATIONS

Term:deactivation of mitotic spindle assembly checkpoint
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Accession:GO:1902426 term browser browse the term
Definition:A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.
Comment:A mitotic spindle assembly checkpoint is either activated or switched off; no other means of reducing the frequency, rate or extent of this process are currently known.
Synonyms:exact_synonym: down regulation of mitotic cell cycle spindle assembly checkpoint;   down regulation of mitotic spindle assembly checkpoint;   downregulation of mitotic cell cycle spindle assembly checkpoint;   downregulation of mitotic spindle assembly checkpoint;   mitotic spindle assembly checkpoint silencing;   mitotic spindle assembly deactivation;   negative regulation of mitotic cell cycle spindle assembly checkpoint
 broad_synonym: negative regulation of mitotic spindle assembly checkpoint
 related_synonym: down regulation of Mad2-dependent checkpoint;   downregulation of Mad2-dependent checkpoint;   inhibition of Mad2-dependent checkpoint;   inhibition of mitotic cell cycle spindle assembly checkpoint;   inhibition of mitotic spindle assembly checkpoint;   negative regulation of Mad2-dependent checkpoint


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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 MAD1 mitotic arrest deficient 1-like 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:139,994,444...140,307,346
Ensembl chr 5:139,994,444...140,307,307 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:46,458,311...46,464,477
Ensembl chr17:46,458,313...46,464,479 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    cellular process 18392
      cell cycle process 1387
        negative regulation of cell cycle process 344
          negative regulation of mitotic spindle assembly checkpoint signaling 5
            deactivation of mitotic spindle assembly checkpoint 3
Path 2
Term Annotations click to browse term
  biological_process 28635
    cellular process 18392
      cellular component organization or biogenesis 7407
        cellular component organization 7211
          organelle organization 3739
            organelle fission 535
              nuclear division 476
                mitotic nuclear division 288
                  mitotic sister chromatid segregation 196
                    regulation of mitotic sister chromatid segregation 62
                      negative regulation of mitotic sister chromatid segregation 55
                        negative regulation of mitotic sister chromatid separation 55
                          negative regulation of mitotic metaphase/anaphase transition 55
                            mitotic spindle assembly checkpoint signaling 53
                              regulation of mitotic cell cycle spindle assembly checkpoint 26
                                negative regulation of mitotic spindle assembly checkpoint signaling 5
                                  deactivation of mitotic spindle assembly checkpoint 3
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