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ONTOLOGY REPORT - ANNOTATIONS

Term:BCOR complex
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Accession:GO:0140261 term browser browse the term
Definition:A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10.
Synonyms:exact_synonym: BCL6 corepressor (BCOR) complex;   BCOR/BCORL1 complex;   PRC1.1 complex;   non-canonical BCOR-PRC1.1 complex;   non-canonical PRC1-BCOR complex


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BCOR complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcor BCL6 co-repressor part_of ISO (PMID:16943429) RGD PMID:16943429 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613 		JBrowse link
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Path 1
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  cellular_component 20811
    protein-containing complex 6431
      nuclear protein-containing complex 1304
        nuclear ubiquitin ligase complex 45
          BCOR complex 1
Path 2
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  cellular_component 20811
    cellular anatomical entity 20571
      organelle 13997
        membrane-bounded organelle 12597
          intracellular membrane-bounded organelle 12048
            nucleus 7480
              nuclear protein-containing complex 1304
                nuclear ubiquitin ligase complex 45
                  BCOR complex 1
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