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ONTOLOGY REPORT - ANNOTATIONS


Term:endothelial to hematopoietic transition
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Accession:GO:0098508 term browser browse the term
Definition:The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.



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endothelial to hematopoietic transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPI1 Spi-1 proto-oncogene involved_in ISO (MGI:6508505|PMID:25252941) ARUK-UCL PMID:25252941 MGI:6508505 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17924
    developmental process 6840
      anatomical structure morphogenesis 3003
        cell morphogenesis 1136
          endothelial to hematopoietic transition 1
Path 2
Term Annotations click to browse term
  biological_process 17924
    biological regulation 12446
      regulation of biological process 12082
        regulation of cellular process 11572
          regulation of cell adhesion 824
            negative regulation of cell adhesion 329
              negative regulation of cell-cell adhesion 220
                delamination 6
                  endothelial to hematopoietic transition 1
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