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TIR domain binding - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:TIR domain binding
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Accession:GO:0070976 term browser browse the term
Definition:Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.
Synonyms:exact_synonym: Toll-Interleukin receptor domain binding

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TIR domain binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr15:1,276,804...1,281,811
Ensembl chr15:1,276,798...1,281,166 		JBrowse link
G PRKCD protein kinase C delta enables ISO PMID:17161867 BHF-UCL PMID:17161867 RGD:8554532 NCBI chr22:14,561,401...14,592,877
Ensembl chr22:14,565,282...14,592,873 		JBrowse link
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  molecular_function 19851
    binding 18044
      protein binding 14898
        protein domain specific binding 821
          TIR domain binding 2
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