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ONTOLOGY REPORT - ANNOTATIONS

Term:BRCA1-A complex
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Accession:GO:0070531 term browser browse the term
Definition:A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.
Synonyms:only_in_taxon: NCBITaxon:6072 ! Eumetazoa


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BRCA1-A complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRAXAS1 abraxas 1, BRCA1 A complex subunit part_of IEA Ensembl GO_REF:0000107 NCBI chr 8:135,002,297...135,021,205
Ensembl chr 8:135,002,321...135,023,335 		JBrowse link
G BABAM1 BRISC and BRCA1 A complex member 1 part_of IEA
IBA		 InterPro
Ensembl
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:60,398,170...60,407,742
Ensembl chr 2:60,398,191...60,407,557 		JBrowse link
G BABAM2 BRISC and BRCA1 A complex member 2 part_of IEA
IBA		 Ensembl
UniProt
InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:110,897,250...111,328,414
Ensembl chr 3:110,897,360...111,328,402 		JBrowse link
G BARD1 BRCA1 associated RING domain 1 part_of IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:117,049,483...117,135,889
Ensembl chr15:117,047,845...117,175,851 		JBrowse link
G BRCA1 BRCA1 DNA repair associated part_of IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 part_of IEA
IBA		 InterPro
UniProt
Ensembl
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:125,383,392...125,439,082
Ensembl chr  X:125,383,414...125,439,082 		JBrowse link
G HK3 hexokinase 3 part_of IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 2:81,042,401...81,060,832
Ensembl chr 2:81,042,755...81,060,826 		JBrowse link
G MPND MPN domain containing part_of IBA GO_Central GO_REF:0000033 NCBI chr 2:74,445,660...74,455,928
Ensembl chr 2:74,445,662...74,455,881 		JBrowse link
G MTPN myotrophin part_of IEA TreeGrafter GO_REF:0000118 NCBI chr18:13,330,049...13,395,297
Ensembl chr18:13,330,029...13,395,460 		JBrowse link
G UIMC1 ubiquitin interaction motif containing 1 part_of IEA
ISS
IBA		 InterPro
UniProt
Ensembl
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:80,895,631...81,040,712
Ensembl chr 2:80,929,267...81,036,448 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18687
    protein-containing complex 6005
      nuclear protein-containing complex 1244
        BRCA1-A complex 10
Path 2
Term Annotations click to browse term
  cellular_component 18687
    cellular anatomical entity 18466
      organelle 12444
        membrane-bounded organelle 11406
          intracellular membrane-bounded organelle 10861
            nucleus 6843
              nuclear protein-containing complex 1244
                BRCA1-A complex 10
paths to the root