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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA (guanine(37)-N1)-methyltransferase activity
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Accession:GO:0052906 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.
Synonyms:exact_synonym: tRNA (guanine(37)-N(1))-methyltransferase activity;   tRNA (guanosine(37)-N(1))-methyltransferase activity;   tRNA (guanosine(37)-N1-)-methyltransferase activity
 related_synonym: tRNA (m(1)G(37)) methyltransferase activity;   tRNA-(N(1)G37) methyltransferase activity;   transfer RNA (m(1)G(37)) methyltransferase activity
 xref: EC:2.1.1.228;   MetaCyc:RXN-12458;   RHEA:36899;   Reactome:R-HSA-6782859 "TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe)"


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tRNA (guanine(37)-N1)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRMT5 tRNA methyltransferase 5 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 8:35,952,183...35,960,681
Ensembl chr 8:35,952,365...35,960,945 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5722
      catalytic activity, acting on a nucleic acid 613
        catalytic activity, acting on RNA 380
          RNA methyltransferase activity 65
            tRNA methyltransferase activity 30
              tRNA (guanine) methyltransferase activity 13
                tRNA (guanine(37)-N1)-methyltransferase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21949
    catalytic activity 5722
      transferase activity 2313
        transferase activity, transferring one-carbon groups 216
          methyltransferase activity 201
            RNA methyltransferase activity 65
              tRNA methyltransferase activity 30
                tRNA (guanine) methyltransferase activity 13
                  tRNA (guanine(37)-N1)-methyltransferase activity 1
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