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ONTOLOGY REPORT - ANNOTATIONS

Term:arachidonate 8(R)-lipoxygenase activity
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Accession:GO:0047677 term browser browse the term
Definition:Catalysis of the reaction: arachidonate + O2 = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
Comment:This activity produces the R-enantiomer of HPETE, 8(R)-HPETE. For the reaction producing the S-enantiomer, see GO:0036403.
Synonyms:narrow_synonym: 8-lipoxygenase activity
 broad_synonym: arachidonate 8-lipoxygenase activity
 related_synonym: 8(R)-lipoxygenase activity;   arachidonate:oxygen 8-oxidoreductase activity
 xref: EC:1.13.11.40;   KEGG_REACTION:R01594;   MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN;   RHEA:14985


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arachidonate 8(R)-lipoxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12B arachidonate 12-lipoxygenase, 12R type enables IEA Ensembl GO_REF:0000107 NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552 		JBrowse link
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  molecular_function 18798
    catalytic activity 5740
      oxidoreductase activity 780
        dioxygenase activity 107
          oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 29
            arachidonate 8(R)-lipoxygenase activity 1
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