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Ontology Browser
Term:
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702)
Annotations: Rat: (28) Mouse: (26) Human: (25) Chinchilla: (21) Bonobo: (27) Dog: (29) Squirrel: (29) Pig: (26) Naked Mole-rat: (24) Green Monkey: (25)
Parent Terms Term With Siblings Child Terms
1,2-dihydroxynaphthalene dioxygenase activity 
2-oxoglutarate-dependent dioxygenase activity +   
3-butenylglucosinolate 2-hydroxylase activity 
alpha-ketoglutarate-dependent xanthine dioxygenase activity 
inositol oxygenase activity  
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor +   
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +  
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +   
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
plasmanylethanolamine desaturase activity  
tryptophan 2'-dioxygenase activity 
 1-hydroxy-2-naphthoate 1,2-dioxygenase activity 
 2,3-dihydroxy-p-cumate dioxygenase activity 
 2,3-dihydroxybenzoate 2,3-dioxygenase activity 
 2,3-dihydroxybenzoate 3,4-dioxygenase activity 
 2,3-dihydroxybiphenyl 1,2-dioxygenase activity 
 2,3-dihydroxyindole 2,3-dioxygenase activity 
 2,4'-dihydroxyacetophenone dioxygenase activity 
 2,5-dihydroxypyridine 5,6-dioxygenase activity 
 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity 
 3,4-dihydroxyphenylacetate 2,3-dioxygenase activity 
 3-carboxyethylcatechol 2,3-dioxygenase activity 
 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity 
 3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity 
 3-hydroxyanthranilate 3,4-dioxygenase activity  
 4-hydroxycatechol 1,2-dioxygenase activity 
 4-hydroxymandelate synthase activity  
 4-hydroxyphenylpyruvate dioxygenase activity  
 5,6-dimethylbenzimidazole synthase activity 
 7,8-dihydroxykynurenate 8,8a-dioxygenase activity 
 9-cis-10'-apo-beta-carotenal cleavage oxygenase activity 
 9-cis-beta-carotene 9',10'-cleavage oxygenase activity 
 acetylacetone-cleaving enzyme activity 
 acireductone dioxygenase (Ni2+-requiring) activity  
 acireductone dioxygenase [iron(II)-requiring] activity  
 all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity 
 all-trans-beta-apo-10'-carotenal cleavage oxygenase activity 
 arachidonate 12(R)-lipoxygenase activity  
 arachidonate 12(S)-lipoxygenase activity  
 arachidonate 15-lipoxygenase activity  
 arachidonate 5-lipoxygenase activity  
 arachidonate 8(R)-lipoxygenase activity  
 arachidonate 8(S)-lipoxygenase activity  
 beta,beta-carotene-9',10'-cleaving oxygenase activity  
 beta-carotene 15,15'-dioxygenase activity  
 biphenyl-2,3-diol 1,2-dioxygenase activity 
 caffeate 3,4-dioxygenase activity 
 carotenoid dioxygenase activity +   
 catechol 1,2-dioxygenase activity 
 catechol 2,3-dioxygenase activity 
 chloridazon-catechol dioxygenase activity 
 chlorite O2-lyase activity 
 cysteamine dioxygenase activity  
 cysteine dioxygenase activity  
 fatty acid alpha-dioxygenase activity 
 gallate dioxygenase activity 
 gentisate 1,2-dioxygenase activity 
 homogentisate 1,2-dioxygenase activity  
 hydroxyquinol 1,2-dioxygenase activity 
 indole 2,3-dioxygenase activity 
 indoleamine 2,3-dioxygenase activity  
 lignostilbene alpha beta-dioxygenase activity 
 linoleate 11-lipoxygenase activity 
 linoleate 13S-lipoxygenase activity  
 linoleate 8R-lipoxygenase activity 
 linoleate 9S-lipoxygenase activity  
 linolenate 9R-lipoxygenase activity 
 p-cumate 2,3-dioxygenase activity 
 protocatechuate 3,4-dioxygenase activity 
 protocatechuate 4,5-dioxygenase activity 
 pyrogallol 1,2-oxygenase activity 
 quercetin 2,3-dioxygenase activity  
 stizolobate synthase activity 
 stizolobinate synthase activity 
 sulfur dioxygenase activity  
 sulfur oxygenase/reductase activity 
 tryptophan 2,3-dioxygenase activity  
 violaxanthin oxygenase activity 

Synonyms
Xrefs: EC:1.13.11 ;   Reactome:R-HSA-2161775 "ALOX12 oxidises LTA4 to LXA4" ;   Reactome:R-HSA-9916401 "ALOX12 oxidises LTA4 to LXB4" ;   reactome:R-HSA-2161907 "ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4" ;   reactome:R-HSA-2161917 "ALOX5 oxidises 15S-HpETE to LXA4/B4" ;   reactome:R-HSA-5164399 "BCO2:Fe2+ cleaves betaC to APO10al and bION" ;   reactome:R-HSA-9018880 "Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE" ;   reactome:R-HSA-9020274 "ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA" ;   reactome:R-HSA-9026408 "PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3" ;   reactome:R-HSA-9026918 "Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA"
Definition Sources: GOC:mah

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