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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear pore linkers
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Accession:GO:0044612 term browser browse the term
Definition:A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p).
Synonyms:related_synonym: Nic96 complex;   Nup82 complex


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  cellular_component 20624
    protein-containing complex 6602
      nuclear protein-containing complex 1276
        nuclear pore linkers 0
Path 2
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  cellular_component 20624
    cellular anatomical entity 20386
      organelle 13799
        membrane-bounded organelle 12396
          intracellular membrane-bounded organelle 11845
            nucleus 7395
              nuclear protein-containing complex 1276
                nuclear pore 77
                  nuclear pore linkers 0
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