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ONTOLOGY REPORT - ANNOTATIONS

Term:5'-3' DNA helicase activity
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Accession:GO:0043139 term browser browse the term
Definition:Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.
Synonyms:exact_synonym: 5' to 3' DNA helicase activity;   ATP-dependent 5' to 3' DNA helicase activity;   ATP-dependent 5'-3' DNA helicase activity
 narrow_synonym: DNA helicase IV activity
 alt_id: GO:0008722;   GO:0043141
 xref: EC:5.6.2.3;   Reactome:R-HSA-6782131 "ERCC2-facilitated RNA Pol II backtracking in TC-NER"


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5'-3' DNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRIP1 BRCA1 interacting helicase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr17:55,786,568...55,973,366
Ensembl chr17:60,901,073...61,083,462 		JBrowse link
G DDX11 DEAD/H-box helicase 11 enables ISO (PMID:18499658) GO_Central PMID:18499658 NCBI chr12:55,176,165...55,207,123 JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit enables IEA Ensembl GO_REF:0000107 NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819 		JBrowse link
G HELB DNA helicase B enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:22,571,448...22,607,417
Ensembl chr12:23,078,732...23,114,134 		JBrowse link
G HELZ2 helicase with zinc finger 2 enables IEA TreeGrafter GO_REF:0000118 Ensembl chr20:61,483,623...61,498,083 JBrowse link
G IGHMBP2 immunoglobulin mu DNA binding protein 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:63,991,285...64,028,430
Ensembl chr11:67,294,195...67,331,659 		JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr15:43,756,605...43,766,631
Ensembl chr15:62,041,461...62,052,311 		JBrowse link
G SLC25A16 solute carrier family 25 member 16 enables IEA Ensembl GO_REF:0000107 NCBI chr10:64,898,024...64,956,541
Ensembl chr10:67,506,006...67,549,308
Ensembl chr10:67,506,006...67,549,308 		JBrowse link
G TWNK twinkle mtDNA helicase enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr10:97,588,811...97,595,663
Ensembl chr10:101,065,096...101,071,407 		JBrowse link
G ZGRF1 zinc finger GRF-type containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:105,026,069...105,128,226
Ensembl chr 4:115,590,311...115,686,089 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17494
    ATP-dependent activity 577
      helicase activity 139
        DNA helicase activity 59
          5'-3' DNA helicase activity 10
Path 2
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      catalytic activity, acting on a nucleic acid 593
        catalytic activity, acting on DNA 244
          ATP-dependent activity, acting on DNA 119
            DNA helicase activity 59
              5'-3' DNA helicase activity 10
paths to the root