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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA endoreduplication
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Accession:GO:0042023 term browser browse the term
Definition:Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
Comment:Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.
Synonyms:exact_synonym: DNA endoreplication;   DNA re-duplication
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


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DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zpr1 ZPR1 zinc finger involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,202,519...12,212,257
Ensembl chrNW_004624784:12,202,519...12,213,120
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) UniProt PMID:17875940 NCBI chrNW_004624785:5,248,434...5,260,623
Ensembl chrNW_004624785:5,247,731...5,260,736
JBrowse link
positive regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 involved_in ISO (MGI:5449497|PMID:23064266)
(PMID:23064266)
UniProt PMID:23064266 MGI:5449497 NCBI chrNW_004624750:21,010,347...21,063,655
Ensembl chrNW_004624750:21,010,339...21,063,757
JBrowse link
G E2f8 E2F transcription factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624766:10,652,749...10,670,886
Ensembl chrNW_004624766:10,652,745...10,669,909
JBrowse link
regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (PMID:19090619) MGI PMID:19090619 NCBI chrNW_004624730:71,068,112...71,100,121
Ensembl chrNW_004624730:71,068,112...71,100,225
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15258
    cellular process 14889
      cell cycle process 1178
        cell cycle DNA replication 38
          DNA endoreduplication 5
            negative regulation of DNA endoreduplication 1
            positive regulation of DNA endoreduplication 2
            regulation of DNA endoreduplication + 4
Path 2
Term Annotations click to browse term
  biological_process 15258
    cellular process 14889
      metabolic process 9701
        primary metabolic process 8629
          nucleobase-containing compound metabolic process 4601
            nucleic acid metabolic process 4140
              DNA metabolic process 849
                DNA replication 246
                  DNA-templated DNA replication 148
                    cell cycle DNA replication 38
                      DNA endoreduplication 5
                        negative regulation of DNA endoreduplication 1
                        positive regulation of DNA endoreduplication 2
                        regulation of DNA endoreduplication + 4
paths to the root