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ONTOLOGY REPORT - ANNOTATIONS

Term:TRAMP complex
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Accession:GO:0031499 term browser browse the term
Definition:A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
Synonyms:narrow_synonym: TRAMP4 complex;   TRAMP5 complex;   Trf4 complex;   Trf4 poly(A) polymerase complex;   Trf4p-Air2p-Mtr4p polyadenylation complex
 xref: Wikipedia:TRAMP_complex


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TRAMP complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTREX Mtr4 exosome RNA helicase part_of IEA Ensembl GO_REF:0000107 NCBI chr16:34,478,227...34,605,508
Ensembl chr16:34,478,272...34,606,096 		JBrowse link
G TENT4A terminal nucleotidyltransferase 4A part_of IEA TreeGrafter GO_REF:0000118 NCBI chr16:75,217,212...75,259,805
Ensembl chr16:75,217,219...75,258,556 		JBrowse link
G TENT4B terminal nucleotidyltransferase 4B part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 6:34,603,157...34,669,779
Ensembl chr 6:34,605,529...34,669,278 		JBrowse link
G ZCCHC7 zinc finger CCHC-type containing 7 part_of IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:237,820,675...238,068,505
Ensembl chr 1:237,820,363...238,068,305 		JBrowse link
G ZCCHC8 zinc finger CCHC-type containing 8 part_of IEA Ensembl GO_REF:0000107 NCBI chr14:30,264,397...30,288,068
Ensembl chr14:30,264,291...30,288,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18687
    protein-containing complex 6005
      nuclear protein-containing complex 1244
        TRAMP complex 5
Path 2
Term Annotations click to browse term
  cellular_component 18687
    cellular anatomical entity 18466
      organelle 12444
        membrane-bounded organelle 11406
          intracellular membrane-bounded organelle 10861
            nucleus 6843
              nuclear protein-containing complex 1244
                TRAMP complex 5
paths to the root