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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
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Accession:GO:0030697 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + uridine54 in tRNA = 5-methyluridine54 in tRNA + H+ + S-adenosyl-L-homocysteine.
Synonyms:exact_synonym: S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity;   S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity;   tRNA (uracil(54)-C(5))-methyltransferase activity, S-adenosyl methionine-dependent
 broad_synonym: RUMT;   ribothymidyl synthase activity
 related_synonym: M5U-methyltransferase activity;   RUMT activity;   S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity;   tRNA uracil 5-methyltransferase activity;   tRNA:m(5)U54-methyltransferase activity;   tRNA:m5U54-methyltransferase activity;   transfer RNA uracil 5-methyltransferase activity;   transfer RNA uracil methylase activity
 alt_id: GO:0009021
 xref: EC:2.1.1.35;   MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN;   RHEA:42712


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tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRMT2A tRNA methyltransferase 2 homolog A enables IEA Ensembl GO_REF:0000107 NCBI chr22:2,872,328...2,877,732
Ensembl chr22:18,544,736...18,550,174 		JBrowse link
G TRMT2B tRNA methyltransferase 2 homolog B enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr  X:90,210,740...90,253,863
Ensembl chr  X:100,347,795...100,389,981 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      transferase activity 2182
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 201
            S-adenosylmethionine-dependent methyltransferase activity 167
              tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent 2
Path 2
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      transferase activity 2182
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 201
            RNA methyltransferase activity 62
              tRNA methyltransferase activity 32
                tRNA (uridine) methyltransferase activity 5
                  tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent 2
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