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ONTOLOGY REPORT - ANNOTATIONS

Term:single-strand selective uracil DNA N-glycosylase activity
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Accession:GO:0017065 term browser browse the term
Definition:Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
Synonyms:exact_synonym: single-strand selective monofunctional uracil-DNA glycosylase activity
 xref: reactome:R-HSA-110221 "Cleavage of uracil by SMUG1 glycosylase"


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single-strand selective uracil DNA N-glycosylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smug1 single-strand-selective monofunctional uracil-DNA glycosylase 1 enables ISO
IDA		 (PMID:12161446), (PMID:12718543) RGD PMID:12161446 PMID:12718543 PMID:12718543 RGD:634191 NCBI chr 7:134,288,565...134,302,179
Ensembl chr 7:134,287,675...134,297,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20731
    catalytic activity 6124
      catalytic activity, acting on a nucleic acid 633
        catalytic activity, acting on DNA 256
          DNA N-glycosylase activity 13
            deaminated base DNA N-glycosylase activity 3
              uracil DNA N-glycosylase activity 3
                single-strand selective uracil DNA N-glycosylase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 20731
    catalytic activity 6124
      hydrolase activity 2599
        hydrolase activity, acting on glycosyl bonds 133
          hydrolase activity, hydrolyzing N-glycosyl compounds 33
            DNA N-glycosylase activity 13
              deaminated base DNA N-glycosylase activity 3
                uracil DNA N-glycosylase activity 3
                  single-strand selective uracil DNA N-glycosylase activity 1
paths to the root