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ONTOLOGY REPORT - ANNOTATIONS

Term:rRNA (cytosine-C5-)-methyltransferase activity
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Accession:GO:0009383 term browser browse the term
Definition:Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.
Synonyms:narrow_synonym: rRNA (cytosine-C5-967)-methyltransferase activity;   rRNA m5C967 methyltransferase activity
 xref: reactome:R-HSA-6790944 "NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447";   reactome:R-HSA-6793057 "NSUN4 methylates cytidine-841 of 12S rRNA yielding 5-methylcytidine-841"


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rRNA (cytosine-C5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOP2 NOP2 nucleolar protein enables IEA TreeGrafter GO_REF:0000118 NCBI chr12:6,687,763...6,699,234
Ensembl chr12:6,606,036...6,617,260 		JBrowse link
G NSUN4 NOP2/Sun RNA methyltransferase 4 enables ISO (PMID:21531335), (PMID:23022348) Reactome PMID:21531335 PMID:23022348 NCBI chr 1:45,642,980...45,696,476
Ensembl chr 1:46,999,749...47,024,152 		JBrowse link
G NSUN5 NOP2/Sun RNA methyltransferase 5 enables IEA Ensembl GO_REF:0000107 Ensembl chr 7:80,455,353...80,461,316 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19165
    catalytic activity 5366
      transferase activity 2154
        transferase activity, transferring one-carbon groups 205
          methyltransferase activity 193
            C-methyltransferase activity 6
              rRNA (cytosine-C5-)-methyltransferase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 19165
    catalytic activity 5366
      transferase activity 2154
        transferase activity, transferring one-carbon groups 205
          methyltransferase activity 193
            S-adenosylmethionine-dependent methyltransferase activity 162
              rRNA methyltransferase activity 21
                rRNA (cytosine) methyltransferase activity 4
                  rRNA (cytosine-C5-)-methyltransferase activity 3
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