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ONTOLOGY REPORT - ANNOTATIONS

Term:rRNA methyltransferase activity
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Accession:GO:0008649 term browser browse the term
Definition:Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.
Synonyms:xref: Reactome:R-HSA-9911509 "RMTases methylate 16S ribosomal RNA"


show annotations for term's descendants           Sort by:
rRNA methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbl fibrillarin enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506 		JBrowse link
G Fbll1 fibrillarin-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:20,762,716...20,764,359
Ensembl chr10:20,761,581...20,764,670 		JBrowse link
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 enables IEA GO_REF:0000002
GO_REF:0000104 		InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr10:91,180,945...91,187,389
Ensembl chr10:91,680,753...91,687,179 		JBrowse link
G Nsun4 NOP2/Sun RNA methyltransferase 4 enables ISO
IEA 		(PMID:23022348)
GO_REF:0000107 		RGD
Ensembl		 PMID:23022348 GO_REF:0000107 NCBI chr 5:134,749,024...134,773,630
Ensembl chr 5:134,749,024...134,775,401 		JBrowse link
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dimt1 DIM1 rRNA methyltransferase and ribosome maturation factor enables ISO
IEA 		(PMID:25851604)
GO_REF:0000107 		RGD
Ensembl		 PMID:25851604 GO_REF:0000107 NCBI chr 2:38,343,086...38,368,242
Ensembl chr 2:40,076,570...40,101,787 		JBrowse link
rRNA (adenine-N6,N6-)-dimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dimt1 DIM1 rRNA methyltransferase and ribosome maturation factor enables ISO
IEA
IBA 		(PMID:25851604)
GO_REF:0000002
GO_REF:0000104
GO_REF:0000033 		RGD
InterPro
UniProt
GO_Central		 PMID:25851604 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:38,343,086...38,368,242
Ensembl chr 2:40,076,570...40,101,787 		JBrowse link
G Tfb1m transcription factor B1, mitochondrial enables IEA
ISO
IBA
ISS 		GO_REF:0000104
(PMID:12496758), (PMID:23303773), (PMID:31251801)
GO_REF:0000033
GO_REF:0000024
(PMID:19356719)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000117 		UniProt
RGD
GO_Central
Ensembl
InterPro		 PMID:12496758 PMID:19356719 PMID:23303773 PMID:31251801 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:46,520,510...46,567,004
Ensembl chr 1:46,524,435...46,566,948 		JBrowse link
G Tfb2m transcription factor B2, mitochondrial enables IEA
IBA 		GO_REF:0000104
GO_REF:0000002
GO_REF:0000033 		UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr13:93,810,859...93,828,678
Ensembl chr13:93,810,731...93,828,594 		JBrowse link
rRNA (adenine-N6-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl5 methyltransferase 5, N6-adenosine enables ISO
IEA 		(PMID:31328227), (PMID:32217665), (PMID:33357433), (PMID:33428944), (PMID:35033535)
GO_REF:0000107
(PMID:32783360) 		RGD
Ensembl		 PMID:31328227 PMID:32217665 PMID:32783360 PMID:33357433 PMID:33428944 More... GO_REF:0000107 NCBI chr 3:75,033,605...75,046,359
Ensembl chr 3:75,026,861...75,045,831 		JBrowse link
G Tfb2m transcription factor B2, mitochondrial enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr13:93,810,859...93,828,678
Ensembl chr13:93,810,731...93,828,594 		JBrowse link
G Zcchc4 zinc finger CCHC-type containing 4 enables ISO
IBA
IEA
ISS 		(PMID:30531910), (PMID:31328227), (PMID:31695039), (PMID:31799605)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
GO_REF:0000002 		RGD
GO_Central
Ensembl
UniProt
InterPro		 PMID:30531910 PMID:31328227 PMID:31695039 PMID:31799605 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:58,165,467...58,207,071
Ensembl chr14:62,378,269...62,419,544 		JBrowse link
rRNA (cytosine-C5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop2 NOP2 nucleolar protein enables ISO
IBA
IEA 		(PMID:26196125), (PMID:36161484)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:26196125 PMID:36161484 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:159,618,966...159,630,697 		JBrowse link
G Nsun4 NOP2/Sun RNA methyltransferase 4 enables ISO (PMID:21531335), (PMID:23022348) RGD PMID:21531335 PMID:23022348 NCBI chr 5:134,749,024...134,773,630
Ensembl chr 5:134,749,024...134,775,401 		JBrowse link
G Nsun5 NOP2/Sun RNA methyltransferase 5 enables ISO
IEA 		(PMID:31428936), (PMID:31722427)
GO_REF:0000117
GO_REF:0000107
(PMID:31722427) 		RGD
UniProt
Ensembl		 PMID:31428936 PMID:31722427 GO_REF:0000107 GO_REF:0000117 NCBI chr12:26,930,204...26,935,887
Ensembl chr12:26,930,863...26,936,130 		JBrowse link
rRNA (cytosine-N4-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl15 methyltransferase 15, mitochondrial 12S rRNA N4-cytidine enables ISO
IBA
IEA 		(PMID:31665743), (PMID:32371392)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:31665743 PMID:32371392 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:95,586,855...95,764,392
Ensembl chr 3:116,041,632...116,217,095 		JBrowse link
rRNA (guanine) methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bud23 BUD23, rRNA methyltransferase and ribosome maturation factor enables ISO
IEA
IBA 		(PMID:25851604)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000033 		RGD
Ensembl
InterPro
GO_Central		 PMID:25851604 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:27,266,093...27,277,300
Ensembl chr12:27,265,521...27,277,297 		JBrowse link
G ENSRNOG00000063747 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:91,180,945...91,187,389
Ensembl chr10:91,680,753...91,687,179 		JBrowse link
G Mrm1 mitochondrial rRNA methyltransferase 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:69,690,406...69,697,326
Ensembl chr10:70,188,748...70,194,131 		JBrowse link
rRNA (guanosine-2'-O-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mrm1 mitochondrial rRNA methyltransferase 1 enables ISO
IEA 		(PMID:25074936), (PMID:35177605)
GO_REF:0000107 		RGD
Ensembl		 PMID:25074936 PMID:35177605 GO_REF:0000107 NCBI chr10:69,690,406...69,697,326
Ensembl chr10:70,188,748...70,194,131 		JBrowse link
G Mrm3 mitochondrial rRNA methyltransferase 3 enables ISO
IEA 		(PMID:24036117), (PMID:25074936), (PMID:35177605)
GO_REF:0000107 		RGD
Ensembl		 PMID:24036117 PMID:25074936 PMID:35177605 GO_REF:0000107 NCBI chr10:61,594,155...61,623,659
Ensembl chr10:61,593,999...61,600,865 		JBrowse link
rRNA (pseudouridine) methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Emg1 EMG1 N1-specific pseudouridine methyltransferase enables ISO
IEA
IBA 		(PMID:20047967)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033 		RGD
InterPro
Ensembl
GO_Central		 PMID:20047967 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:159,195,545...159,203,826
Ensembl chr 4:159,195,564...159,203,826 		JBrowse link
rRNA (uridine-2'-O-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000063747 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:91,180,945...91,187,389
Ensembl chr10:91,680,753...91,687,179 		JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 enables ISO
IEA
IBA 		(PMID:25074936), (PMID:35177605)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:25074936 PMID:35177605 GO_REF:0000033 GO_REF:0000107 NCBI chr12:19,423,448...19,428,662
Ensembl chr12:19,423,452...19,428,621 		JBrowse link
rRNA (uridine-C5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt2b tRNA methyltransferase 2 homolog B enables ISO (PMID:31948311), (PMID:34556860)
(PMID:31736397) 		RGD PMID:31736397 PMID:31948311 PMID:34556860 NCBI chr  X:101,716,656...101,777,105 JBrowse link
rRNA (uridine-N3-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fdxacb1 ferredoxin-fold anticodon binding domain containing 1 enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:60,009,818...60,014,625 JBrowse link
G Spout1 SPOUT domain containing methyltransferase 1 enables IEA
ISO 		GO_REF:0000107
(PMID:39671501) 		Ensembl
RGD		 PMID:39671501 GO_REF:0000107 NCBI chr 3:33,849,007...33,856,564
Ensembl chr 3:33,849,007...33,856,269 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21117
    catalytic activity 6224
      catalytic activity, acting on a nucleic acid 698
        catalytic activity, acting on RNA 424
          RNA methyltransferase activity 64
            rRNA methyltransferase activity 21
              rRNA (adenine) methyltransferase activity + 5
              rRNA (cytosine) methyltransferase activity + 4
              rRNA (guanine) methyltransferase activity + 5
              rRNA (pseudouridine) methyltransferase activity + 1
              rRNA (uridine) methyltransferase activity + 6
Path 2
Term Annotations click to browse term
  molecular_function 21117
    catalytic activity 6224
      transferase activity 2499
        transferase activity, transferring one-carbon groups 222
          methyltransferase activity 210
            S-adenosylmethionine-dependent methyltransferase activity 172
              rRNA methyltransferase activity 21
                rRNA (adenine) methyltransferase activity + 5
                rRNA (cytosine) methyltransferase activity + 4
                rRNA (guanine) methyltransferase activity + 5
                rRNA (pseudouridine) methyltransferase activity + 1
                rRNA (uridine) methyltransferase activity + 6
paths to the root