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ONTOLOGY REPORT - ANNOTATIONS

Term:4-hydroxy-2-oxoglutarate aldolase activity
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Accession:GO:0008700 term browser browse the term
Definition:Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
Synonyms:related_synonym: 2-keto-4-hydroxybutyrate aldolase activity;   2-keto-4-hydroxyglutarate aldolase activity;   2-keto-4-hydroxyglutaric aldolase activity;   2-oxo-4-hydroxyglutarate aldolase activity;   2-oxo-4-hydroxyglutaric aldolase activity;   4-hydroxy-2-ketoglutarate aldolase activity;   4-hydroxy-2-ketoglutaric aldolase activity;   4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming);   4-hydroxy-2-oxoglutarate glyoxylate-lyase activity;   DL-4-hydroxy-2-ketoglutarate aldolase activity;   KHG-aldolase activity;   hydroxyketoglutarate aldolase activity;   hydroxyketoglutaric aldolase activity
 xref: EC:4.1.3.16;   MetaCyc:4OH2OXOGLUTARALDOL-RXN;   RHEA:18169;   reactome:R-HSA-6784423 "HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate"


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4-hydroxy-2-oxoglutarate aldolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 enables ISO
IBA		 (PMID:21998747)
GO_REF:0000033		 RGD
GO_Central		 PMID:21998747 GO_REF:0000033 NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568 		JBrowse link
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  molecular_function 20483
    catalytic activity 6036
      lyase activity 211
        carbon-carbon lyase activity 53
          oxo-acid-lyase activity 5
            4-hydroxy-2-oxoglutarate aldolase activity 1
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