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ONTOLOGY REPORT - ANNOTATIONS

Term:protein processing involved in protein targeting to mitochondrion
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Accession:GO:0006627 term browser browse the term
Definition:The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
Synonyms:broad_synonym: mitochondrial processing
 related_synonym: mitochondrial protein processing during import


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protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IMMP1L inner mitochondrial membrane peptidase subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:31,396,011...31,473,342
Ensembl chr11:31,285,619...31,362,843 		JBrowse link
G IMMP2L inner mitochondrial membrane peptidase subunit 2 acts_upstream_of_or_within ISO (PMID:15814844) MGI PMID:15814844 NCBI chr 7:102,647,212...103,536,293 JBrowse link
G MIPEP mitochondrial intermediate peptidase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:5,040,237...5,207,674
Ensembl chr13:23,334,267...23,500,582 		JBrowse link
G PMPCA peptidase, mitochondrial processing subunit alpha involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:107,483,608...107,499,176
Ensembl chr 9:136,464,070...136,477,569 		JBrowse link
G PMPCB peptidase, mitochondrial processing subunit beta involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12433926 GO_REF:0000107 GO_REF:0000118 RGD:13463464 NCBI chr 7:95,288,747...95,320,294
Ensembl chr 7:108,033,235...108,050,302 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr12:117,867,453...117,887,968
Ensembl chr12:121,241,112...121,261,777 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    localization 5258
      establishment of localization 4571
        establishment of protein localization 1598
          protein targeting 294
            protein targeting to mitochondrion 101
              protein processing involved in protein targeting to mitochondrion 6
                negative regulation of protein processing involved in protein targeting to mitochondrion 1
                regulation of protein processing involved in protein targeting to mitochondrion + 1
Path 2
Term Annotations click to browse term
  biological_process 16644
    localization 5258
      macromolecule localization 2955
        cellular macromolecule localization 2532
          protein localization 2520
            protein localization to organelle 1018
              protein localization to mitochondrion 132
                establishment of protein localization to mitochondrion 122
                  protein targeting to mitochondrion 101
                    protein processing involved in protein targeting to mitochondrion 6
                      negative regulation of protein processing involved in protein targeting to mitochondrion 1
                      regulation of protein processing involved in protein targeting to mitochondrion + 1
paths to the root