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ONTOLOGY REPORT - ANNOTATIONS

Term:methionine-tRNA ligase activity
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Accession:GO:0004825 term browser browse the term
Definition:Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).
Synonyms:exact_synonym: methionyl-tRNA synthetase activity
 related_synonym: L-methionine:tRNAMet ligase (AMP-forming);   MetRS activity;   methionine translase activity;   methionyl-transfer RNA synthetase activity;   methionyl-transfer ribonucleate synthetase activity;   methionyl-transfer ribonucleic acid synthetase activity
 xref: EC:6.1.1.10;   MetaCyc:METHIONINE--TRNA-LIGASE-RXN;   RHEA:13481;   reactome:R-HSA-379994 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate";   reactome:R-HSA-380157 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate"


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methionine-tRNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MARS1 methionyl-tRNA synthetase 1 enables IEA InterPro
Ensembl
UniProt
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr12:31,410,231...31,438,015
Ensembl chr12:31,668,708...31,693,839 		JBrowse link
G MARS2 methionyl-tRNA synthetase 2, mitochondrial enables IEA Ensembl
UniProt
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:84,954,833...84,957,871
Ensembl chr2B:202,847,478...202,849,259 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      ligase activity 167
        ligase activity, forming carbon-oxygen bonds 43
          aminoacyl-tRNA ligase activity 43
            methionine-tRNA ligase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      catalytic activity, acting on a nucleic acid 593
        catalytic activity, acting on RNA 366
          catalytic activity, acting on a tRNA 132
            aminoacyl-tRNA ligase activity 43
              methionine-tRNA ligase activity 2
paths to the root