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ONTOLOGY REPORT - ANNOTATIONS
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Term:
asparagine-tRNA ligase activity
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Accession:
GO:0004816
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Definition:
Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H+.
Synonyms:
exact_synonym:
asparaginyl-tRNA synthetase activity
related_synonym:
L-asparagine:tRNAAsn ligase (AMP-forming); asparagine translase activity; asparaginyl transfer RNA synthetase activity; asparaginyl transfer ribonucleic acid synthetase activity; asparaginyl-transfer ribonucleate synthetase activity; asparagyl-transfer RNA synthetase activity
xref:
EC:6.1.1.22; KEGG_REACTION:R03648; MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN; RHEA:11180; reactome:R-HSA-379996 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate"; reactome:R-HSA-380227 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate"
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Rat (2)
Mouse (2)
Human (2)
Chinchilla (1)
Bonobo (2)
Dog (3)
Squirrel (2)
Pig (2)
Green Monkey (2)
Naked Mole-rat (1)
All
Genes (2)
asparagine-tRNA ligase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Nars1
asparaginyl-tRNA synthetase 1
enables
ISO
IBA
(PMID:32738225), (PMID:9421509)
GO_REF:0000033
RGD
GO_Central
PMID:9421509
PMID:32738225
GO_REF:0000033
NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
G
Nars2
asparaginyl-tRNA synthetase 2, mitochondrial
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:151,300,446...151,412,086
Ensembl chr 1:151,300,467...151,413,521
Term paths to the root
one shortest
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one longest
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one shortest and longest
all
Path 1
Term
Annotations
molecular_function
20626
catalytic activity
6028
ligase activity
178
ligase activity, forming carbon-oxygen bonds
45
aminoacyl-tRNA ligase activity
45
asparagine-tRNA ligase activity
2
Path 2
Term
Annotations
molecular_function
20626
catalytic activity
6028
catalytic activity, acting on a nucleic acid
649
catalytic activity, acting on RNA
397
catalytic activity, acting on a tRNA
136
aminoacyl-tRNA ligase activity
45
asparagine-tRNA ligase activity
2