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ONTOLOGY REPORT - ANNOTATIONS

Term:asparagine-tRNA ligase activity
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Accession:GO:0004816 term browser browse the term
Definition:Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H+.
Synonyms:exact_synonym: asparaginyl-tRNA synthetase activity
 related_synonym: L-asparagine:tRNAAsn ligase (AMP-forming);   asparagine translase activity;   asparaginyl transfer RNA synthetase activity;   asparaginyl transfer ribonucleic acid synthetase activity;   asparaginyl-transfer ribonucleate synthetase activity;   asparagyl-transfer RNA synthetase activity
 xref: EC:6.1.1.22;   KEGG_REACTION:R03648;   MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN;   RHEA:11180;   reactome:R-HSA-379996 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate";   reactome:R-HSA-380227 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate"


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asparagine-tRNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nars1 asparaginyl-tRNA synthetase 1 enables ISO
IBA		 (PMID:32738225), (PMID:9421509)
GO_REF:0000033		 RGD
GO_Central		 PMID:9421509 PMID:32738225 GO_REF:0000033 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622 		JBrowse link
G Nars2 asparaginyl-tRNA synthetase 2, mitochondrial enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:151,300,446...151,412,086
Ensembl chr 1:151,300,467...151,413,521 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      ligase activity 180
        ligase activity, forming carbon-oxygen bonds 45
          aminoacyl-tRNA ligase activity 45
            asparagine-tRNA ligase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      catalytic activity, acting on a nucleic acid 638
        catalytic activity, acting on RNA 399
          catalytic activity, acting on a tRNA 134
            aminoacyl-tRNA ligase activity 45
              asparagine-tRNA ligase activity 2
paths to the root