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ONTOLOGY REPORT - ANNOTATIONS

Term:alanine-tRNA ligase activity
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Accession:GO:0004813 term browser browse the term
Definition:Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
Synonyms:exact_synonym: alanyl-tRNA synthetase activity
 related_synonym: Ala-tRNA synthetase activity;   AlaRS;   L-alanine:tRNAAla ligase (AMP-forming);   alanine tRNA synthetase activity;   alanine transfer RNA synthetase activity;   alanine translase activity;   alanine-transfer RNA ligase activity;   alanyl-transfer RNA synthetase activity;   alanyl-transfer ribonucleate synthase activity;   alanyl-transfer ribonucleate synthetase activity;   alanyl-transfer ribonucleic acid synthetase activity
 xref: EC:6.1.1.7;   MetaCyc:ALANINE--TRNA-LIGASE-RXN;   RHEA:12540;   reactome:R-HSA-379864 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate";   reactome:R-HSA-380177 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate"

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alanine-tRNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS1 alanyl-tRNA synthetase 1 enables ISO
IEA		 RGD
UniProt
InterPro
TreeGrafter
Ensembl		 PMID:2040280 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:2302982 NCBI chr 5:53,399,717...53,433,472
Ensembl chr 5:53,395,638...53,433,461 		JBrowse link
G AARS2 alanyl-tRNA synthetase 2, mitochondrial enables IEA InterPro
Ensembl
UniProt
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr17:27,855,688...27,869,427
Ensembl chr17:27,855,713...27,870,409 		JBrowse link
G LOC103243378 alanyl-tRNA editing protein Aarsd1 enables IEA InterPro GO_REF:0000002 NCBI chr16:63,323,110...63,337,167
Ensembl chr16:63,322,885...63,339,596 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19845
    catalytic activity 5464
      ligase activity 168
        ligase activity, forming carbon-oxygen bonds 42
          aminoacyl-tRNA ligase activity 42
            alanine-tRNA ligase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 19845
    catalytic activity 5464
      catalytic activity, acting on a nucleic acid 597
        catalytic activity, acting on RNA 366
          catalytic activity, acting on a tRNA 134
            aminoacyl-tRNA ligase activity 42
              alanine-tRNA ligase activity 3
paths to the root